Systemic Inflammatory Response Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-03-17Clinical Trial Update: Myostatin and Irisin Levels in Predicting the Outcome of Patients With Systemic Inflammation: A Prospective Observational Study
A completed prospective observational study from Charles University evaluates whether myostatin and irisin levels can predict outcomes in pa…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: Improving Health Outcomes With Kefir [NA]
A clinical trial is recruiting to study the effects of kefir on inflammatory response, type 2 diabetes, and cardiovascular outcomes.
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CLINICAL_TRIALS research · 2026-03-10Clinical Trial Update: Implementation of Timely Management of Sepsis and Septic Shock Protocol in the Emergency Department and Intensive Care Unit: A Quality Improvement Project at AFHJ [NA]
A quality improvement clinical trial at AFHJ aims to implement a timely sepsis and septic shock management protocol in the emergency departm…
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CLINICAL_TRIALS trial_result · 2026-01-23Clinical Trial Update: Cytokine Adsorption During Complex Cardiac Surgery: a Controlled Randomized Trial [NA]
A randomized controlled trial evaluating cytokine adsorption during complex cardiac surgery has completed, investigating whether this therap…
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CLINICAL_TRIALS research · 2025-12-18Clinical Trial Update: Correlation of Memory CD8+ T Cells With Sepsis Severity and Mortality: a Single-center, Unblinded, Prospective, Non-interventional, Observational Study
This completed observational study explored whether memory CD8+ T cell levels correlate with sepsis severity and mortality. It was single-ce…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Determinants of Vascular Leakage During Systemic Inflammatory Response Syndrome
A clinical trial is ongoing to identify determinants of vascular leakage in systemic inflammatory response syndrome; the study is currently …
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Dynamics of microRNA Expression and Systemic Inflammatory Response in POCD After Cardiac Surgery
A completed clinical trial examining how microRNA expression and the systemic inflammatory response relate to postoperative cognitive dysfun…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Modulation of Molecular Fingerprinting in Pediatric Sepsis
A pediatric clinical trial is recruiting to study modulation of molecular fingerprinting in systemic inflammatory response syndrome, potenti…
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: Conventional Ultrafiltration Versus Dilutional Ultrafiltration in Pediatric CPB Patients
A pediatric trial comparing conventional ultrafiltration versus dilutional ultrafiltration during cardiopulmonary bypass to address systemic…
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: A Study of Auxora in Patients With Acute Pancreatitis and Accompanying SIRS [Phase 2]
Phase 2 study of Auxora in acute pancreatitis with systemic inflammatory response syndrome completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-02Clinical Trial Update: Goal-directed Resuscitative Interventions During Pediatric Inter-facility Transport (The GRIPIT Trial) [NA]
The GRIPIT trial, which studied goal-directed resuscitative interventions during pediatric inter-facility transport, has been terminated; no…
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CLINICAL_TRIALS trial_result · 2025-08-29Clinical Trial Update: Perioperative Blood Adiponectin Dynamics and Systemic Infflamatory Response After Major Colorectal Surgery
This completed clinical trial evaluated perioperative adiponectin dynamics and systemic inflammatory response after major colorectal surgery…
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CLINICAL_TRIALS research · 2025-08-06Clinical Trial Update: A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG [Phase 1, Phase 2]
A clinical trial update for a Phase 1/Phase 2 study at Ain Shams University comparing dexmedetomidine and methylprednisolone to modulate inf…
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CLINICAL_TRIALS trial_result · 2025-07-22Clinical Trial Update: Effect of Lactiplantibacillus Plantarum DAD-13 on Inflammatory Markers in ICU Sepsis Patients [NA]
Completed clinical trial assessing the probiotic Lactiplantibacillus plantarum DAD-13 for reducing inflammatory markers in ICU sepsis patien…
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Clinical Microbial Species & Antibiotic Resistance ID in ED Patients Presenting With Infection - is Rapid ID Possible & Accurate?
A clinical trial investigating rapid identification of microbial species and antibiotic resistance in emergency department patients with inf…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: Initial Feasibility Study of the CycloPE® Device [NA]
This clinical trial update notes an initial feasibility study of the CycloPE device for sepsis-related conditions; the trial is currently ac…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: CRP/Albumin Ratio as a Predictive Inflammatory Marker for Postoperative SIRS and/or Sepsis
The trial evaluated whether the CRP/albumin ratio can predict postoperative systemic inflammatory response syndrome and sepsis.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Evaluation of Intraoperative Dexmedetomidine Use in Patients Undergoing Surgical Aortic Valve Replacement [Phase 3]
Phase 3 trial evaluating intraoperative dexmedetomidine use in patients undergoing surgical aortic valve replacement has completed.
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CLINICAL_TRIALS trial_result · 2025-03-28Clinical Trial Update: Effect of Pectin and Inulin Fibre Supplementation on Glucose and ANS Modulation [NA]
A completed clinical trial evaluating whether pectin and inulin fiber supplementation affects glucose regulation and autonomic nervous syste…
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CLINICAL_TRIALS withdrawal · 2025-03-13Clinical Trial Update: High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery [NA]
This clinical trial evaluating high cut-off dialysis in patients with systemic inflammatory response syndrome after cardiac surgery has been…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock [NA]
A terminated clinical trial evaluating high cut-off CVVHD in patients with acute kidney failure after systemic inflammatory response syndrom…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Use of EBPT in Critically Ill Patients With AKI and/or Multiorgan Failure
This entry reports ongoing recruitment for a study evaluating extracorporeal blood purification therapy (EBPT) in critically ill patients wi…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Development of a Web-based Multicenter Registry on the Use of oXiris Membrane for EBPTs in Critically Ill Patients
A web-based multicenter registry is being developed to collect data on the use of the oXiris membrane for extracorporeal blood purification …
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Extracorporeal Blood Purification Therapy in Critically Ill Patients (GlobalARRT)
The GlobalARRT trial is evaluating extracorporeal blood purification therapy in critically ill patients. Recruitment is ongoing, including p…
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CLINICAL_TRIALS trial_result · 2025-02-07Clinical Trial Update: Determining the Fingerprint of Endotoxin Tolerance [NA]
This completed clinical trial conducted by Radboud University Medical Center investigates the fingerprint of endotoxin tolerance in endotoxe…