Stargardt Disease
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CLINICAL_TRIALS trial_result · 2026-07-31Clinical Trial Update: A Phase 2/3 Trial to Assess the Efficacy and Safety of OCU410ST for Stargardt Disease [Phase 2, Phase 3]
Phase 2/3 trial update for OCU410ST in Stargardt Disease indicating active status with ongoing efficacy and safety assessment.
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Restoration of Central Vision With PRIMA in Patients With Photoreceptor Degeneration [NA]
A clinical trial evaluating PRIMA for photoreceptor degeneration is currently recruiting, focusing on Stargardt disease and retinitis pigmen…
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CLINICAL_TRIALS trial_result · 2026-03-12Clinical Trial Update: Zimura Compared to Sham in Patients With Autosomal Recessive Stargardt Disease (STGD1) [Phase 2]
Phase 2 trial comparing Zimura to sham in autosomal recessive Stargardt disease (STGD1) completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2025-10-31Clinical Trial Update: Phase 3, Randomized, Placebo-Controlled Study of Tinlarebant to Explore Safety and Efficacy in Adolescent Stargardt Disease [Phase 3]
Phase 3 randomized, placebo-controlled study of tinlarebant in adolescents with Stargardt disease has completed, with safety and efficacy da…
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CLINICAL_TRIALS trial_result · 2025-06-12Clinical Trial Update: Phase I/II Follow-up Study of SAR422459 in Patients With Stargardt's Macular Degeneration [Phase 2]
A Phase II follow-up study of SAR422459 for Stargardt disease is currently active but not recruiting, sponsored by Sanofi.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Phase 2 Tolerability and Effects of ALK-001 on Stargardt Disease [Phase 2]
Phase 2 trial evaluating tolerability and effects of ALK-001 in Stargardt disease. The study is currently enrolling by invitation.
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CLINICAL_TRIALS trial_result · 2025-04-27Clinical Trial Update: Phase 1 Safety Study of ALK-001 in Healthy Volunteers [Phase 1]
Phase 1 safety study of ALK-001 in healthy volunteers has completed, assessing safety in humans. It targets retinal degenerative conditions …
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CLINICAL_TRIALS trial_result · 2025-04-22Clinical Trial Update: Function and Imaging Assessments for G1961E-associated Stargardt Disease
This clinical trial update discusses function and imaging assessments for Stargardt disease associated with the ABCA4 G1961E variant, noting…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Sub-retinal Transplantation of hESC Derived RPE(MA09-hRPE)Cells in Patients With Stargardt's Macular Dystrophy [Phase 1, Phase 2]
Astellas Institute for Regenerative Medicine conducted a Phase 1/2 study evaluating sub-retinal transplantation of MA09-hRPE cells for Starg…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Safety and Tolerability of Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial (hESC-RPE) Cells in Patients With Stargardt's Macular Dystrophy (SMD) [Phase 1, Phase 2]
This Phase 1/2 trial evaluated the safety and tolerability of sub-retinal transplantation of human embryonic stem cell–derived retinal pigme…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Long Term Follow Up of Sub-retinal Transplantation of hESC Derived RPE Cells in Stargardt Macular Dystrophy Patients
Long-term follow-up results are reported for sub-retinal transplantation of human embryonic stem cell-derived retinal pigment epithelium cel…
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CLINICAL_TRIALS trial_result · 2024-04-12Clinical Trial Update: This is a Dose-finding Study Followed by 2-year Extension Study to Evaluate Safety and Tolerability of Tinlarebant in Adolescent Subjects With Stargardt Disease [Phase 1, Phase 2]
Phase 1/2 dose-finding and 2-year extension study evaluating the safety and tolerability of tinlarebant in adolescents with Stargardt diseas…
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CLINICAL_TRIALS trial_result · 2024-03-08Clinical Trial Update: Safety and Efficacy of a Single Subretinal Injection of JWK006 Gene Therapy in Subjects With Stargardt Disease(STGD1) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating safety and efficacy of a single subretinal injection of JWK006 gene therapy for Stargardt Disease (STG…
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CLINICAL_TRIALS trial_result · 2023-11-09Clinical Trial Update: Safety and Effects of a Single Intravitreal Injection of vMCO-010 Optogenetic Therapy in Subjects With Stargardt Disease [Phase 2]
Phase 2 trial update on safety and effects of a single intravitreal injection of vMCO-010 optogenetic therapy in Stargardt disease.
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CLINICAL_TRIALS trial_result · 2023-08-03Clinical Trial Update: Safety and Efficacy of Emixustat in Stargardt Disease [Phase 3]
Phase 3 results report the safety and efficacy of Emixustat for Stargardt disease; the trial has completed and results were posted.
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: Pharmacodynamic Study of Emixustat Hydrochloride in Subjects With Macular Atrophy Secondary to Stargardt Disease [Phase 2]
Phase 2 pharmacodynamic study of emixustat hydrochloride in Stargardt disease–related macular atrophy completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-04-27Clinical Trial Update: Study of STG-001 in Subjects With Stargardt Disease [Phase 2]
Phase 2 clinical trial study of STG-001 in Stargardt Disease has completed.
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CLINICAL_TRIALS trial_result · 2020-06-05Clinical Trial Update: Phase I/IIA Study of SAR422459 in Participants With Stargardt's Macular Degeneration [Phase 1, Phase 2]
Phase I/IIA trial of SAR422459 for Stargardt's disease was terminated with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-01Clinical Trial Update: Efficacy of Acupuncture in Macular Diseases [NA]
A completed clinical trial evaluating acupuncture for macular diseases (age-related macular degeneration and Stargardt disease) with results…
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CLINICAL_TRIALS trial_result · 2018-05-09Clinical Trial Update: DHA Supplementation in Patients With STGD3 [NA]
This ClinicalTrials.gov entry reports a completed trial evaluating DHA (docosahexaenoic acid) supplementation in patients with Dominantly In…
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CLINICAL_TRIALS trial_result · 2017-07-21Clinical Trial Update: Intravitreal Bone Marrow-Derived Stem Cells in Patients With Macular Degeneration [NA]
This clinical trial evaluated intravitreal bone marrow-derived stem cell therapy in patients with age-related macular degeneration and Starg…
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CLINICAL_TRIALS trial_result · 2017-07-19Clinical Trial Update: Saffron Supplementation in Stargardt's Disease [Phase 1, Phase 2]
Phase 1/Phase 2 clinical trial evaluating saffron supplementation for Stargardt disease is noted, with the current status listed as unknown.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Effect of DHA Supplements on Macular Function in Patients With Stargardt Macular Dystrophy and Stargardt-like Macular Dystrophy [Phase 1]
Phase 1 trial evaluating whether DHA supplements improve macular function in patients with Stargardt disease and Stargardt-like macular dyst…
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CLINICAL_TRIALS trial_result · 2013-02-13Clinical Trial Update: Microcurrent Stimulation to Treat Macular Degeneration
A completed clinical trial evaluated microcurrent stimulation as a treatment for macular degeneration.