Squamous Cell Carcinoma of Head and Neck
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-20Clinical Trial Update: A Study of Sigvotatug Vedotin in Advanced Solid Tumors [Phase 1]
Phase 1 study of Sigvotatug Vedotin in advanced solid tumors is currently recruiting. The trial targets multiple indications, including non-…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Candida Therapeutic Vaccine in Head and Neck Cancer Patients to Reduce Recurrence [Phase 2]
A Phase 2 clinical trial is evaluating a Candida therapeutic vaccine to reduce recurrence in patients with squamous cell carcinoma of the he…
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CLINICAL_TRIALS trial_result · 2026-04-02Clinical Trial Update: Camrelizumab in Combination With Cetuximab and Chemotherapy for Relapsed/Metastatic HNSCC Patients [Phase 2]
A Phase 2 trial evaluating camrelizumab in combination with cetuximab and chemotherapy for relapsed/metastatic squamous cell carcinoma of th…
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CLINICAL_TRIALS trial_result · 2026-03-31Clinical Trial Update: Study of Xevinapant With Radiation and Chemotherapy for Patients With Head and Neck Cancer [Phase 1]
A Phase 1 study evaluating Xevinapant in combination with radiation and chemotherapy for head and neck cancer has been terminated.
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: A Study of Head and Neck MRI and Tumor Microenvironment Biomarkers [NA]
This clinical trial investigates head and neck MRI and tumor microenvironment biomarkers in squamous cell carcinoma of the head and neck; re…
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CLINICAL_TRIALS research · 2026-03-04Clinical Trial Update: HN-BIO 02: A Phase II Randomized Study of the Effects of Delayed Elective Radiotherapy on Head and Neck MRI and Immune Response Biomarkers [NA]
This clinical trial update announces a Phase II randomized study assessing the effects of delayed elective radiotherapy on head and neck MRI…
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CLINICAL_TRIALS research · 2026-01-28Clinical Trial Update: Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update indicates that TH9619 is being studied in a Phase 1/2 trial for advanced solid tumors, with recruitment ongoing a…
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CLINICAL_TRIALS research · 2026-01-16Clinical Trial Update: A Clinical Trial Evaluating TG4050 in Head and Neck Cancer [Phase 1, Phase 2]
The update describes Transgene's TG4050 in a Phase 1/2 trial for Squamous Cell Carcinoma of Head and Neck, with the study currently active b…
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: A Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced Cancers [Phase 1]
Phase 1 study assessing safety and early efficacy of KFA115 alone and in combination with pembrolizumab in select advanced cancers; the tria…
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CLINICAL_TRIALS research · 2025-11-28Clinical Trial Update: Intraoperative Assessment of Surgical Margins Using Confocal Microscopy in Comparison With Reference Extemporaneous Examination [NA]
This clinical trial evaluates intraoperative margin assessment using confocal microscopy against reference extemporaneous examination in pat…
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: A Study of [225Ac]-FPI-2059 in Adult Participants With Solid Tumours [Phase 1]
A Phase 1 study of [225Ac]-FPI-2059 in adults with solid tumours was terminated.
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: MK-7684A With or Without Other Anticancer Therapies in Participants With Selected Solid Tumors (MK-7684A-005) (KEYVIBE-005) [Phase 2]
Merck completed a Phase 2 trial (MK-7684A-005) evaluating MK-7684A with or without other anticancer therapies in selected solid tumors.
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: A Trial Evaluating the Addition of Nivolumab to Cisplatin-RT for Treatment of Cancers of the Head and Neck [Phase 3]
A Phase 3 clinical trial update evaluating the addition of nivolumab to cisplatin-based chemoradiation for squamous cell carcinoma of the he…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
A clinical trial update describing a study to quantify systemic immunosuppression to personalize cancer therapy and that the trial is curren…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer [Phase 1, Phase 2]
HYPORT is a Phase I/II study evaluating hypofractionated postoperative radiation therapy for squamous cell carcinoma of the head and neck. T…
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: App-based Recording and Optimization of the Nutritional Status in Patients With Head and Neck Tumors During and After Radio(Chemo)Therapy [NA]
An ongoing clinical trial evaluating an app-based approach to recording and optimizing nutritional status in patients with head and neck squ…
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CLINICAL_TRIALS research · 2025-03-26Clinical Trial Update: The Efficacy and Safety of Pucotenlimab Combined With TP Chemotherapy as Neoadjuvant Therapy for Locally Advanced HNSCC [Phase 2]
Phase 2 neoadjuvant trial evaluating pucotenlimab in combination with TP chemotherapy for locally advanced head and neck squamous cell carci…
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: Study of REGN6569 and Cemiplimab in Adult Patients With Advanced Solid Tumor Malignancies [Phase 1]
Phase 1 study evaluating REGN6569 in combination with cemiplimab in adults with advanced solid tumors, including head and neck squamous cell…
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CLINICAL_TRIALS trial_result · 2024-10-16Clinical Trial Update: A Study of ALKS 4230 (Nemvaleukin Alfa) With Pembrolizumab in Head and Neck Cancer [Phase 2]
A Phase 2 trial of ALKS 4230 (nemvaleukin alfa) in combination with pembrolizumab for head and neck squamous cell carcinoma has completed en…
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CLINICAL_TRIALS trial_result · 2023-10-13Clinical Trial Update: Toripalimab in Combined With Cetuximab，Chemotherapy for Conversion Therapy of Locally Nonresectable OCSCC [Phase 2]
Phase 2 trial evaluating toripalimab in combination with cetuximab and chemotherapy for conversion therapy in locally nonresectable oral cav…
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CLINICAL_TRIALS trial_result · 2023-02-01Clinical Trial Update: A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 study of GEN1044 (DuoBody-CD3x5T4) in malignant solid tumors has been terminated with posted results.
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CLINICAL_TRIALS trial_result · 2022-10-13Clinical Trial Update: A Study of Docetaxel for Injection (Albumin-bound) in Combination With Nivolumab in Patients With Head and Neck (SCCHN) [Phase 1, Phase 2]
A clinical trial update for docetaxel albumin-bound with nivolumab in head and neck squamous cell carcinoma (Phase 1/2) with unknown status.
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CLINICAL_TRIALS withdrawal · 2022-02-08Clinical Trial Update: Enoblituzumab Plus MGA012 or MGD013 in Squamous Cell Carcinoma of the Head and Neck [Phase 2, Phase 3]
A clinical trial investigating enoblituzumab with MGA012 or MGD013 in squamous cell carcinoma of the head and neck has been withdrawn.
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CLINICAL_TRIALS trial_result · 2019-01-22Clinical Trial Update: Study of Safety and Efficacy of INC280 and Cetuximab, in Adult c-MET Positive mCRC and HNSCC Patients After Progression on Cetuximab or Panitumumab Therapy [Phase 1]
A Phase 1 trial of INC280 (capmatinib) in combination with Cetuximab in MET-positive adult patients with metastatic colorectal cancer or hea…
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CLINICAL_TRIALS trial_result · 2015-10-08Clinical Trial Update: Study to Evaluate the Response Rate to Therapy With Docetaxel and Cisplatin in Unresectable Locally Advanced Squamous Cell Carcinoma of Head and Neck [Phase 2]
This phase 2 clinical trial evaluated the response rate to a combination of docetaxel and cisplatin in unresectable locally advanced squamou…