Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Testing Afatinib as Potentially Targeted Treatment in Cancers With EGFR Genetic Changes (MATCH - Subprotocol A) [Phase 2]
Phase 2 MATCH subprotocol evaluating afatinib for cancers with EGFR genetic alterations; results have been posted and the trial is active bu…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Indenoisoquinoline LMP744 in Adults With Relapsed Solid Tumors and Lymphomas [Phase 1]
Phase 1 trial of the indenoisoquinoline LMP744 in adults with relapsed solid tumors and lymphomas has completed, with results posted in Dece…
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CLINICAL_TRIALS other · 2024-12-09Clinical Trial Update: A Study of the ILB-3101 in Patients with Advanced Solid Tumors [Phase 1]
This clinical trial update notes that Innolake Biopharm is recruiting for a Phase 1 study of ILB-3101 in patients with advanced solid tumors…
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Irinotecan Liposomes Combined with Temozolomide and Vincristine in the Treatment of Pediatric Patients with Solid Tumors [Phase 1]
This update describes a Phase 1 study evaluating a triplet chemotherapy regimen—liposomal irinotecan combined with temozolomide and vincrist…
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CLINICAL_TRIALS research · 2024-11-26Clinical Trial Update: A Phase II Study of SHR-4602 as Montherapy or in Combination With Other Anti-tumor Therapies in Advanced Solid Tumors [Phase 2]
Phase II study of SHR-4602 as monotherapy or in combination with other anti-tumor therapies for advanced solid tumors; the trial status is n…
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CLINICAL_TRIALS trial_result · 2024-11-25Clinical Trial Update: PAK4 and NAMPT in Patients With Solid Malignancies or NHL (PANAMA) [Phase 1]
Phase 1 PANAMA trial evaluating a dual NAMPT/PAK4 inhibitor in patients with solid tumors or non-Hodgkin lymphoma was terminated, with resul…
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08) [Phase 1, Phase 2]
GI Innovation's GI-102 is being studied in a phase 1/2 trial as a single agent and in combination with pembrolizumab or trastuzumab deruxtec…
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: Study of Continuous OSI-906 Dosing [Phase 1]
A Phase 1 study evaluating continuous dosing of OSI-906 in patients with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-11-20Clinical Trial Update: A Phase 1 Dose-escalation Study of OSI-906 and Erlotinib (Tarceva®) [Phase 1]
A Phase 1 dose-escalation study evaluated the combination of OSI-906 and Erlotinib (Tarceva) in patients with advanced solid tumors; the tri…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Phase I Clinical Study of MBS301 in Treatment of HER2 Positive Recurrent or Metastatic Malignant Solid Tumor [Phase 1]
Phase I clinical trial update for MBS301 in HER2-positive recurrent or metastatic malignant solid tumors; study is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: A Study of TAK-981 in People With Advanced Solid Tumors or Cancers in the Immune System [Phase 1, Phase 2]
Takeda's TAK-981 was studied in Phase 1/2 trials for advanced solid tumors and hematologic malignancies, but the study was terminated with r…
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CLINICAL_TRIALS research · 2024-11-19Clinical Trial Update: A Phase 2 Clinical Study of ABSK061 and ABSK043 [Phase 2]
Abbisko Therapeutics is recruiting for a Phase 2 study of ABSK061 and ABSK043 in multiple cancers, including HER2-positive gastric/gastroeso…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: A Study to Learn About the Study Medicine (Called PF-07220060 in Combination With PF-07104091) In Participants With Breast Cancer and Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating PF-07220060 in combination with PF-07104091 for breast cancer and solid tumors. The study is currently A…
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CLINICAL_TRIALS research · 2024-11-18Clinical Trial Update: A Rollover Study for Subjects Who Completed Participation in IMSA101-101 Trial [Phase 1]
This clinical trial update describes a Phase 1 rollover study for adult subjects who completed participation in the IMSA101-101 trial, spons…
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CLINICAL_TRIALS trial_result · 2024-11-15Clinical Trial Update: Varian ProBeam Proton Therapy System China Clinical Trial (Hefei) [NA]
The Varian ProBeam Proton Therapy System trial conducted in Hefei, China has completed, with results posted on 2024-11-15.
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CLINICAL_TRIALS research · 2024-11-14Clinical Trial Update: The Psychological Impact of COVID-19 on Patients with Solid Malignancies: a Single-Institution Survey Study
The Christie NHS Foundation Trust completed a single-institution survey evaluating the psychological impact of COVID-19 on patients with sol…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: A Study Evaluating Safety and Therapeutic Activity of ANV419 in Patients with Advanced Cancer. [Phase 1]
Phase 1 study evaluating safety and early therapeutic activity of ANV419 in adults with advanced solid tumors, including lung cancer, has co…
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CLINICAL_TRIALS trial_result · 2024-11-08Clinical Trial Update: Nozin in Preventing Respiratory Viral Infections in Patients Undergoing Stem Cell Transplant, PREV-NOSE STUDY [Phase 1]
The PREV-NOSE Phase 1 trial evaluating Nozin to prevent respiratory viral infections in patients undergoing stem cell transplant was termina…
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CLINICAL_TRIALS trial_result · 2024-11-07Clinical Trial Update: A Study to Look at How a Single Oral Dose of 14C-OSI-906 is Absorbed, Broken Down and Eliminated in the Body [Phase 1]
Phase 1 pharmacokinetic study of a single oral dose of 14C-OSI-906 in patients with solid tumors, examining absorption, metabolism, and elim…
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CLINICAL_TRIALS research · 2024-11-07Clinical Trial Update: First-in-human Trial of EGL-001 in Patients with Selected Advanced And/or Metastatic Solid Tumors [Phase 1, Phase 2]
First-in-human Phase 1/2 trial of EGL-001 in adults with selected advanced or metastatic solid tumors, currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Study to Investigate the Absorption, Metabolism and Excretion of [14C] ASP2215 in Patients With Advanced Solid Tumors [Phase 1]
Phase 1 pharmacokinetic study evaluating absorption, metabolism and excretion of [14C] ASP2215 (gilteritinib) in patients with advanced soli…
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1 [Phase 1]
Phase 1 study of MT-6402 in PD-L1-expressing advanced solid tumors, including non-small cell lung cancer and squamous cell carcinoma of the …
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Safety and Pharmacokinetic Study of RRx-001 in Cancer Subjects [Phase 1]
Phase 1 safety and pharmacokinetic data for RRx-001 in cancer patients; the trial (solid tumors and lymphomas) has completed and results wer…
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CLINICAL_TRIALS trial_result · 2024-11-01Clinical Trial Update: Study of ASP1948, Targeting an Immune Modulatory Receptor, in Japanese Patients With Advanced Solid Tumors [Phase 1]
Phase 1 study of ASP1948 in Japanese patients with locally advanced or metastatic solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: A Dose Escalation and Expansion Study of ASP4132 to Subjects With Advanced Refractory Tumors and Lymphoma [Phase 1]
Phase 1 dose-escalation and expansion study of ASP4132 in patients with lymphoma and solid tumors has completed.