Solid Tumors
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: A Dose Escalation Study Of PF-06939999 In Participants With Advanced Or Metastatic Solid Tumors [Phase 1]
A Phase 1 dose-escalation study of PF-06939999 in participants with advanced or metastatic solid tumors was terminated, with results posted …
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: A Study of DSP107 Alone and in Combination with Atezolizumab for Patients with Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of DSP107 alone and in combination with atezolizumab. The study targets patients with a…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: Phase 1 Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of KN510, KN713 [Phase 1]
A Phase 1 trial evaluating the safety, tolerability, and pharmacokinetics of KN510 and KN713 in patients with advanced solid tumors has comp…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: Investigation of PSMA PET/CT as an Imaging Biomarker in Solid Tumors [NA]
This clinical trial update notes the completion of a study evaluating PSMA PET/CT as an imaging biomarker in metastatic castration-resistant…
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CLINICAL_TRIALS research · 2025-01-08Clinical Trial Update: A Prospective, Single-arm Clinical Study of Liposomal Mitoxantrone Combination Regimen in the Treatment of Relapsed and Refractory Solid Tumors in Children, Adolescents and Young Adults [Phase 2]
A Phase 2 prospective, single-arm clinical study evaluating liposomal mitoxantrone in relapsed or refractory solid tumors in children, adole…
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CLINICAL_TRIALS withdrawal · 2025-01-07Clinical Trial Update: Nab-Paclitaxel/STI-3031 Complex (AP160-Complex) for the Treatment of Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 trial of Nab-Paclitaxel in combination with STI-3031 Complex (AP160-Complex) for advanced or metastatic solid tumors has been with…
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: UGT1A1 Genotype-drien Phase I Study of Irinotecan in VIT Regimen for the Treatment of Pediatric R/R Solid Tumors [Phase 1]
Phase I, genotype-guided irinotecan study in a VIT regimen for pediatric relapsed/refractory solid tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-06Clinical Trial Update: Trial Comparing Parenteral Nutrition (PN) Using Eurotubes® vs. 2/3-chamber Bags in Subjects With Solid Tumors Requiring PN (PEKANNUSS)
A clinical trial comparing Eurotubes parenteral nutrition to 2/3-chamber bags in patients with solid tumors was terminated, with no results …
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CLINICAL_TRIALS research · 2024-12-31Clinical Trial Update: Using of Virtual Reality to Relieve Procedural Pain in Pediatric Oncology. [NA]
A completed clinical trial evaluating virtual reality as a non-drug method to relieve procedural pain in pediatric cancer patients. The stud…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: A Phase I Study OfLNF2007 Monotherapy in Patients with Advanced Solid Tumors [Phase 1]
Phase I study of LNF2007 as monotherapy in patients with advanced solid tumors is not yet recruiting. Sponsor: Shandong New Time Pharmaceuti…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: MMP14(MT1-MMP) Targeting Bicyclic Peptide Probe for PET Imaging in Solid Tumors
A clinical trial registry entry describes a bicyclic peptide probe targeting MMP14 (MT1-MMP) for PET imaging in solid tumors, with recruitme…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: Evaluating the Safety, Tolerability, and Pharmacokinetics of BAT1006 [Phase 1]
A Phase 1 trial assessing the safety, tolerability, and pharmacokinetics of BAT1006 in patients with advanced solid tumors has been complete…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors [Phase 1, Phase 2]
Clinical trial evaluating idasanutlin in combination with chemotherapy or venetoclax in pediatric and young adult relapsed/refractory acute …
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Dose Escalation Study of BI 2536 BS in Patients With Advanced Solid Tumours With Repeated Administration in Patients With Clinical Benefit [Phase 1]
A completed Phase 1 dose-escalation study of BI 2536 BS in patients with advanced solid tumors evaluated safety, tolerability, and prelimina…
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CLINICAL_TRIALS research · 2024-12-20Clinical Trial Update: A Phase Ib/II Study Of JS015 Combination Therapy in Advanced Solid Tumors [Phase 1, Phase 2]
A Phase Ib/II clinical trial evaluating JS015 in combination therapy for advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: A Retro-/Prospective, Non-interventional, Cohort Study in Adult Patients With Locally Advanced or Metastatic Tumors With a Neurotrophic Tyrosine Receptor Kinase (NTRK) Gene Fusion, Treated With Larotrectinib
This is a completed non-interventional cohort study in adults with NTRK-fusion solid tumors treated with larotrectinib.
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Intratumoral CAN2109 in Subjects With Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating intratumoral CAN2109 in adults with solid tumors and lymphoma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-12-17Clinical Trial Update: RVU120 (SEL120) in Patients with Relapse/Refractory Metastatic or Advanced Solid Tumors [Phase 1, Phase 2]
This clinical trial update describes RVU120 (SEL120) being tested in Phase 1/2 for patients with advanced, relapsed or refractory solid tumo…
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CLINICAL_TRIALS research · 2024-12-17Clinical Trial Update: A Phase I/II Study to Evaluate the Safety, Pharmacokinetics and Efficacy of PRJ1-3024 in Subjects with Advanced Solid Tumors [Phase 1, Phase 2]
Phase 1/2 trial evaluating the safety, pharmacokinetics and preliminary efficacy of PRJ1-3024 in patients with advanced solid tumors; recrui…
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CLINICAL_TRIALS trial_result · 2024-12-16Clinical Trial Update: A First in Human, Dose Escalation Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors [Phase 1]
First-in-human Phase 1 dose-escalation study of JAB-3068, an SHP2 inhibitor, in adults with advanced solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: AMG 404 in Patients With Advanced Solid Tumors [Phase 1]
Amgen reports Phase 1 results for AMG 404 in patients with advanced solid tumors; the study is completed and results have been posted.
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CLINICAL_TRIALS research · 2024-12-13Clinical Trial Update: Neurocognitive Risks in Children With Solid Tumors
A clinical trial update indicating that recruitment is ongoing for a study examining neurocognitive risks in children with solid tumors.
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: A Clinical Research About CD70-targeted CAR-NKT Cells Therapy in Subjects with Advanced Malignant Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating CD70-targeted CAR-NKT cell therapy for advanced malignant solid tumors; recruitment is ongoing.
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: Phase I/IIa Study of 68GaNOTA-Anti-MMR-VHH2 for PET/CT [Phase 1, Phase 2]
Update on a Phase I/IIa PET imaging trial of 68GaNOTA-Anti-MMR-VHH2 for malignant solid tumors, including breast cancer and melanoma; the st…
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CLINICAL_TRIALS trial_result · 2024-12-10Clinical Trial Update: Testing Palbociclib (PD-0332991) as Potentially Targeting Treatment in Cancers With CDK4 or CDK6 Amplification (MATCH - Subprotocol Z1C) [Phase 2]
Phase 2 MATCH subprotocol Z1C evaluates palbociclib in cancers with CDK4/CDK6 amplification; results have been posted and the trial is curre…