Solid Tumors
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors [Phase 1]
An open-label Phase I study evaluating ASP5878, an oral FGFR1-4 inhibitor, in patients with solid tumors.
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CLINICAL_TRIALS withdrawal · 2024-10-31Clinical Trial Update: Study of SPX-101 in Subjects With Advanced or Refractory Solid Tumors [Phase 1]
The Phase 1 study of SPX-101 in adults with advanced or refractory solid tumors has been withdrawn.
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CLINICAL_TRIALS research · 2024-10-28Clinical Trial Update: A Study of XZB-0004 in Patients With Solid Tumors [Phase 1]
Phase 1 study of XZB-0004 in patients with solid tumors, including non-small cell lung cancer, is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: BT1718 in Patients with Advanced Solid Tumours. [Phase 1, Phase 2]
This clinical trial update reports on BT1718 in patients with advanced solid tumors in Phase 1/2, with the study status completed. Condition…
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CLINICAL_TRIALS other · 2024-10-24Clinical Trial Update: Expanded Access Program for Avapritinib
Expanded Access Program for Avapritinib has ended and is no longer available for patients with solid tumors.
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: A Trial of SHR-7787 Injection in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating SHR-7787 injections in patients with advanced solid tumors is currently recruiting.
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CLINICAL_TRIALS research · 2024-10-18Clinical Trial Update: A Multi-cohort Study of Efbemalenograstim Alfa Injection for Preventing ANC Reduction in Solid Tumor Patients Post Immune-chemotherapy. [NA]
A multi-cohort clinical trial evaluating Efbemalenograstim Alfa Injection to prevent ANC reduction in solid tumor patients following immune-…
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CLINICAL_TRIALS withdrawal · 2024-10-15Clinical Trial Update: ZEN003694 Combined With Niraparib in Patients With Metastatic or Recurrent Solid Tumors [Phase 1]
A Phase 1 trial evaluating ZEN003694 in combination with niraparib for metastatic or recurrent solid tumors, including ovarian cancer, has b…
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CLINICAL_TRIALS trial_result · 2024-10-09Clinical Trial Update: REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma [Phase 1, Phase 2]
Regeneron’s cemiplimab (REGN2810) was studied in pediatric patients with relapsed/refractory solid tumors and CNS tumors, including a safety…
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CLINICAL_TRIALS research · 2024-10-08Clinical Trial Update: A Study to Evaluate the Safety and Tolerability of ETC-1922159 as a Single Agent and in Combination With Pembrolizumab in Advanced Solid Tumours [Phase 1]
This document provides an update on a Phase 1 clinical trial evaluating ETC-1922159 as a single agent and in combination with pembrolizumab …
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CLINICAL_TRIALS trial_result · 2024-10-04Clinical Trial Update: A Study of MK-1088 as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-1088-002) [Phase 1, Phase 2]
A Phase 1/2 study of MK-1088, both as monotherapy and in combination with pembrolizumab, in adults with advanced solid tumors was terminated…
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CLINICAL_TRIALS research · 2024-10-01Clinical Trial Update: Safety and Efficacy of KLS-1 Monotherapy in Malignant Neoplasms [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating KLS-1 as a monotherapy for malignant neoplasms, including chronic lymphocytic leukemia and solid tumors; …
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: PIPA: Combination of PI3 Kinase Inhibitors and PAlbociclib [Phase 1]
Phase 1 trial update of a combination of PI3 kinase inhibitors and Palbociclib (PIPA) for advanced solid tumors and breast cancer has comple…
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CLINICAL_TRIALS trial_result · 2024-09-26Clinical Trial Update: Phase I Trial of ONX-0801 Once Weekly or Alternate Weekly [Phase 1]
Phase I trial evaluating ONX-0801 given weekly or every other week in patients with solid tumors has completed.
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CLINICAL_TRIALS trial_result · 2024-09-25Clinical Trial Update: A First-in-Human Study of JAB-3068 (SHP2 Inhibitor) in Adult Patients With Advanced Solid Tumors in China [Phase 1, Phase 2]
First-in-human study of JAB-3068, an SHP2 inhibitor, in adults with advanced solid tumors in China, including non-small cell lung cancer, he…
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Expanded Access to Provide GL-ONC1 for the Treatment of Advanced Cancers With No Standard of Care
Expanded access program for GL-ONC1 in patients with advanced solid tumors and acute myeloid leukemia is no longer available.
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CLINICAL_TRIALS research · 2024-09-25Clinical Trial Update: Efficacy and Safety of Duloxetine in Chinese Solid Tumor Patients with Taxanes-induced Painful Peripheral Neuropathy [Phase 2]
Phase 2 trial assessing the efficacy and safety of duloxetine for taxanes-induced painful peripheral neuropathy in Chinese patients with sol…
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CLINICAL_TRIALS trial_result · 2024-09-23Clinical Trial Update: A Study of CC-122 to Assess the Safety and Tolerability in Japanese Patients With Advanced Solid Tumors and Non-Hodgkin's Lymphoma (NHL) [Phase 1]
A Phase 1 study of CC-122 in Japanese patients with advanced solid tumors and Non-Hodgkin lymphoma was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: IMP4297 in Combination With Temozolomide in Patients With Advanced Solid Tumors and Small Cell Lung Cancer [Phase 1, Phase 2]
IMP4297 combined with temozolomide was studied in patients with advanced solid tumors and small cell lung cancer in Phase 1/Phase 2 trials, …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: A Study to Test Different Doses of BI 3011441 in Japanese People With Different Types of Advanced Cancer (NRAS/KRAS Mutation Positive) [Phase 1]
A Phase 1 dose-escalation study of BI 3011441 in Japanese patients with NRAS- or KRAS-mutant advanced solid tumors has completed and posted …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Safety, Pharmacokinetics and Anti-tumor Activity of RP12146, in Patients With Solid Tumors [Phase 1]
Phase 1 study shows safety, pharmacokinetics and preliminary anti-tumor activity of RP12146 in patients with solid tumors, including extensi…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Phase I/II Study of XZP-3287 in Metastasis Solid Tumors [Phase 1, Phase 2]
This is a status update for an ongoing Phase I/II trial of XZP-3287 in metastatic solid tumors and advanced breast cancer, currently active …
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: ENB003 Plus Pembrolizumab Phase 1b/2a in Solid Tumors [Phase 1, Phase 2]
A Phase 1b/2a trial evaluating ENB003 in combination with pembrolizumab for various solid tumors, including melanoma, ovarian cancer, pancre…
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CLINICAL_TRIALS research · 2024-09-19Clinical Trial Update: A Clinical Study of the Safety, Tolerability, Pharmacokinetics, and Initial Efficacy of HRS-4508 Monotherapy in Patients With Advanced or Metastatic Solid Tumors [Phase 1]
This is a Phase 1 clinical study overview evaluating HRS-4508 monotherapy in patients with advanced or metastatic solid tumors, focusing on …
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors [Phase 1]
Phase 1 first-in-human study of oral TP-1287 in patients with advanced solid tumors, including specific sarcoma subtypes, has been terminate…