Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-08-25Clinical Trial Update: Alimta Plus Gemcitabine for Advanced Sarcoma [Phase 2]
Phase 2 trial evaluating Alimta (pemetrexed) plus gemcitabine for advanced soft tissue sarcoma has completed with results posted.
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FDA approval · 2020-08-17FDA Approved: VOTRIENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for VOTRIENT (pazopanib hydrochloride) by Novartis Pharmaceuticals Corporation. The approval updates…
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CLINICAL_TRIALS trial_result · 2020-08-10Clinical Trial Update: Pazopanib Hydrochloride and Topotecan Hydrochloride in Treating Patients With Metastatic Soft Tissue and Bone Sarcomas [Phase 2]
Phase 2 trial evaluating pazopanib hydrochloride combined with topotecan hydrochloride in adults with metastatic or recurrent soft tissue an…
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CLINICAL_TRIALS trial_result · 2020-07-29Clinical Trial Update: Daily Oral Regorafenib for Chemotherapy-Refractory, Metastatic and Locally Advanced Angiosarcoma [Phase 2]
Phase 2 trial evaluating daily oral regorafenib in chemotherapy-refractory, metastatic, and locally advanced angiosarcoma; study completed w…
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EMA label_change · 2020-07-24Authorised uses of cancer medicine Yondelis unchanged following review of new data
The EMA review concluded that the authorised uses of Yondelis (trabectedin) remain unchanged after evaluating new data.
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FDA approval · 2020-07-17FDA Approved: VOTRIENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for VOTRIENT (pazopanib hydrochloride) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2020-07-14Clinical Trial Update: The Combination of Sintilimab and AI (Doxorubicin, ADM/Ifosfamide, IFO) for the First Line Treatment of Select Type of Metastatic/Unresectable Soft Tissue Sarcoma [Phase 2]
Phase 2 trial investigating the combination of Sintilimab with doxorubicin/Ifosfamide as first-line therapy for select metastatic/unresectab…
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CLINICAL_TRIALS trial_result · 2020-06-17Clinical Trial Update: TVEC and Preop Radiation for Sarcoma (4 ml Dose) [Phase 1, Phase 2]
Phase 1/2 trial evaluating intralesional talimogene laherparepvec (T-VEC) with preoperative radiation for soft tissue sarcoma; results have …
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CLINICAL_TRIALS trial_result · 2020-06-16Clinical Trial Update: Nivolumab With or Without Ipilimumab in Treating Patients With Metastatic Sarcoma That Cannot Be Removed by Surgery [Phase 2]
A Phase 2 trial evaluating nivolumab with or without ipilimumab in metastatic or unresectable sarcoma shows results from a completed study.
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CLINICAL_TRIALS trial_result · 2020-06-11Clinical Trial Update: Sorafenib Tosylate, Combination Chemotherapy, Radiation Therapy, and Surgery in Treating Patients With High-Risk Stage IIB-IV Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating sorafenib tosylate in combination with chemotherapy, radiation, and surgery for high-risk soft tissue sarcoma (stag…
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CLINICAL_TRIALS trial_result · 2020-06-09Clinical Trial Update: Pazopanib as Front-Line Therapy in Patients With Non-Resectable or Metastatic Soft Tissue Sarcomas Who Are Not Candidates for Chemotherapy [Phase 2]
Phase 2 clinical trial update evaluating pazopanib as frontline therapy for non-resectable or metastatic soft tissue sarcoma patients who ar…
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FDA approval · 2020-06-02FDA Approved: VOTRIENT — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for VOTRIENT (pazopanib hydrochloride) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS withdrawal · 2020-05-19Clinical Trial Update: Pegylated Liposomal Doxorubicin Versus Pirarubicin Plus Ifosfamide, Dacarbazine in Locally Advanced, Unresectable or Metastatic Soft-tissue Sarcoma [Phase 2, Phase 3]
Phase 2/3 trial comparing pegylated liposomal doxorubicin to pirarubicin plus ifosfamide and dacarbazine for locally advanced, unresectable,…
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CLINICAL_TRIALS trial_result · 2020-05-14Clinical Trial Update: Study to Compare the Safety and Efficacy of CMB305 With Atezolizumab to Atezolizumab Alone in Participants With Sarcoma (IMDZ-C232/V943A-002) [Phase 2]
Phase 2 trial evaluating CMB305 with atezolizumab versus atezolizumab alone in various sarcomas has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-05-12Clinical Trial Update: A Phase 1B Dose-escalation and Phase 2a Study of Carotuximab (TRC105) in Combination With Pazopanib in Patients With Advanced Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1B dose-escalation and Phase 2a study of Carotuximab (TRC105) with Pazopanib in advanced soft tissue sarcoma completed; results posted…
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CLINICAL_TRIALS trial_result · 2020-04-22Clinical Trial Update: PLD and IFO As First-line Treatment for Patients With Advanced or Metastatic STS [Phase 2]
A Phase 2 clinical trial investigates pegylated liposomal doxorubicin (PLD) with ifosfamide as first-line treatment for advanced or metastat…
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CLINICAL_TRIALS trial_result · 2020-04-16Clinical Trial Update: A Phase 3, Randomized, Double-blind, Placebo-controlled Study For Subjects With Locally-advanced Unresectable or Metastatic Synovial Sarcoma (V943-003, IMDZ-04-1702) [Phase 3]
Phase 3 trial in synovial sarcoma was terminated; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-04-08Clinical Trial Update: Flavopiridol in Treating Patients With Recurrent, Locally Advanced, or Metastatic Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial investigating flavopiridol for recurrent, locally advanced, or metastatic soft tissue sarcoma has been completed.
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CLINICAL_TRIALS trial_result · 2020-04-06Clinical Trial Update: A Phase II Trial Comparing Gemcitabine and Pazopanib Versus Gemcitabine and Docetaxel for Patients With Advanced Soft Tissue Sarcoma [Phase 2]
Phase II trial comparing gemcitabine with pazopanib versus gemcitabine with docetaxel for advanced soft tissue sarcoma has completed; result…
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CLINICAL_TRIALS trial_result · 2020-02-28Clinical Trial Update: Dose-Escalation and Expansion Trial of NC-6300 in Patients With Advanced Solid Tumors or Soft Tissue Sarcoma [Phase 1, Phase 2]
Phase 1/2 dose-escalation and expansion trial of NC-6300 in advanced solid tumors and soft tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2020-01-28Clinical Trial Update: FLuoresence Image Guided Surgery With A VEGF-targeted Tracer in Soft-tissue Sarcomas in Humans Approach With Bevacizumab-IRDye 800CW [Phase 1, Phase 2]
Clinical trial update for a VEGF-targeted tracer (Bevacizumab-IRDye 800CW) used in fluorescence image-guided surgery for soft-tissue sarcoma…
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CLINICAL_TRIALS trial_result · 2020-01-27Clinical Trial Update: Clinical Study of PD-1 Monoclonal Antibody SHR-1210 and Apatinib in Advanced NSCLC, Soft Tissue Sarcoma, and Uterine Cancer [Phase 2]
Phase 2 clinical trial evaluating PD-1 monoclonal antibody SHR-1210 in combination with apatinib for advanced non-small cell lung cancer, so…
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CLINICAL_TRIALS trial_result · 2019-12-26Clinical Trial Update: Endostar Combined With Chemotherapy for Stage Ⅳ Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating Endostar in combination with chemotherapy for stage IV soft tissue sarcoma has completed recruitment.
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CLINICAL_TRIALS trial_result · 2019-12-17Clinical Trial Update: A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma [Phase 3]
Phase 3 trial evaluating doxorubicin with olaratumab in advanced or metastatic soft tissue sarcoma has completed and results have been poste…
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CLINICAL_TRIALS trial_result · 2019-11-21Clinical Trial Update: A Study of Olaratumab and Doxorubicin in Participants With Advanced Soft Tissue Sarcoma [Phase 1]
Phase 1 trial evaluating olaratumab in combination with doxorubicin in advanced soft tissue sarcoma has completed with results posted.