Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-11-04Clinical Trial Update: Neoadjuvant Durvalumab and Tremelimumab Plus Radiation for High Risk Soft-Tissue Sarcoma [Phase 1, Phase 2]
The clinical trial evaluating neoadjuvant durvalumab and tremelimumab in combination with radiation for high-risk soft tissue sarcoma has be…
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CLINICAL_TRIALS trial_result · 2024-10-31Clinical Trial Update: Cemiplimab for Secondary Angiosarcomas [Phase 2]
This report indicates the completion of a Phase 2 trial evaluating cemiplimab for secondary angiosarcoma and related locally advanced or met…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: A Study of CCT301-59 CAR T Therapy in Adult Subjects With Recurrent or Refractory Solid Tumors [Phase 1]
Phase 1 trial of CCT301-59 CAR T therapy in adults with recurrent or refractory solid tumors has been terminated. The study included soft ti…
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CLINICAL_TRIALS trial_result · 2024-10-24Clinical Trial Update: Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) with Pulmonary Metastases [Phase 1, Phase 2]
This clinical trial update reports a Phase 1/2 study of liposomal annamycin for soft-tissue sarcoma with pulmonary metastases. The study sta…
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CLINICAL_TRIALS trial_result · 2024-10-23Clinical Trial Update: A Study of Olaratumab (LY3012207) Plus Pembrolizumab in Participants With Advanced or Metastatic Soft Tissue Sarcoma [Phase 1]
A Phase 1 study of olaratumab (LY3012207) plus pembrolizumab in advanced or metastatic soft tissue sarcoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2024-10-21Clinical Trial Update: Study of the Safety, Pharmacokinetics and Efficacy of Tinostamustine in Patients With Advanced Solid Tumors. [Phase 1, Phase 2]
Clinical trial update reporting safety, pharmacokinetics, and efficacy findings for tinostamustine in patients with advanced solid tumors, i…
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CLINICAL_TRIALS trial_result · 2024-09-04Clinical Trial Update: Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 Pediatric MATCH trial evaluating samotolisib in pediatric patients with relapsed or refractory tumors harboring TSC or PI3K/mTOR mut…
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CLINICAL_TRIALS trial_result · 2024-08-29Clinical Trial Update: A Study Of Naxitamab , Granulocyte Macrophage Colony Stimulating Factor For Patients With Relapsed /Refractory , Soft Tissue or Anti GD2 Immunotherapy Refractory Neuroblastoma [Phase 2]
Phase 2 study of naxitamab in combination with GM-CSF for relapsed/refractory neuroblastoma and anti-GD2 immunotherapy-refractory soft tissu…
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CLINICAL_TRIALS trial_result · 2024-08-13Clinical Trial Update: Trial of Sunitinib and/or Nivolumab Plus Chemotherapy in Advanced Soft Tissue and Bone Sarcomas [Phase 1, Phase 2]
A completed Phase 1/2 trial evaluating sunitinib and/or nivolumab with chemotherapy in advanced soft tissue and bone sarcomas.
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CLINICAL_TRIALS trial_result · 2024-07-23Clinical Trial Update: Pembrolizumab and Radiation Therapy in Treating Patients With Intermediate or High-Grade Soft Tissue Sarcoma [Phase 1, Phase 2]
Clinical trial update for pembrolizumab with radiation therapy in intermediate- or high-grade soft tissue sarcoma (Phase 1/2). The study has…
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CLINICAL_TRIALS trial_result · 2024-07-08Clinical Trial Update: Low Dose Continuous Cyclophosphamide vs Standard Doxorubicin in Advanced Sarcoma Elderly Patients [Phase 3]
A Phase 3 study comparing low-dose continuous cyclophosphamide to standard doxorubicin in elderly patients with advanced soft tissue sarcoma…
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CLINICAL_TRIALS trial_result · 2024-07-03Clinical Trial Update: Dendritic Cell Vaccine for Children and Adults With Sarcoma [Phase 1]
This Phase 1 trial update reports the completion of a dendritic cell vaccine study in children and adults with soft tissue and bone sarcoma.
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CLINICAL_TRIALS trial_result · 2024-06-18Clinical Trial Update: Theranostics in Soft Tissue Sarcoma Using a Vascular Disruption Approach [Phase 1]
Phase 1 trial evaluating a vascular disruption theranostic approach for soft tissue sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Phase 3 Study to Treat Patients With Soft Tissue Sarcomas [Phase 3]
Phase 3 study in metastatic, locally advanced or unresectable soft tissue sarcoma completed; results were posted in June 2024.
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Lymphodepletion Plus Adoptive Cell Therapy With High Dose IL-2 in Adolescent and Young Adult Patients With Soft Tissue Sarcoma [Phase 1]
A Phase 1 trial evaluating lymphodepletion followed by adoptive cell therapy with high-dose interleukin-2 in adolescent and young adult pati…
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Preliminary Efficacy and Safety of INNO-206 Compared to Doxorubicin in Advanced Soft Tissue Sarcoma [Phase 2]
Phase 2 trial comparing INNO-206 to doxorubicin in advanced soft tissue sarcoma reports preliminary efficacy and safety results.
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CLINICAL_TRIALS trial_result · 2024-05-29Clinical Trial Update: Study to Investigate the Safety and Activity of Aldoxorubicin Plus Ifosfamide/Mesna in Subjects With Metastatic Soft Tissue Sarcoma [Phase 1, Phase 2]
A completed Phase 1/Phase 2 trial evaluating aldoxorubicin in combination with ifosfamide/Mesna for metastatic, unresectable soft tissue sar…
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CLINICAL_TRIALS trial_result · 2024-05-14Clinical Trial Update: PBI-MST-01 (NCT04541108) Substudy MSD-03: Intratumoral Microdosing of Pembrolizumab Alone and With MK-0482 or MK-4830 in HNSCC or STS [EARLY_Phase 1]
An early-phase trial evaluating intratumoral microdosing of pembrolizumab alone or with MK-0482 or MK-4830 in head and neck squamous cell ca…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Itacitinib in Treating Patients With Refractory Metastatic/Advanced Sarcomas [Phase 1]
Itacitinib was studied in a Phase 1 trial for patients with refractory metastatic/advanced sarcomas, but the study status is TERMINATED.
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CLINICAL_TRIALS trial_result · 2024-04-08Clinical Trial Update: A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma [Phase 3]
Phase 3 trial comparing L19TNF+Doxorubicin versus Doxorubicin alone as first-line therapy for advanced or metastatic soft tissue sarcoma is …
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CLINICAL_TRIALS trial_result · 2024-03-13Clinical Trial Update: Nab-Sirolimus and Pazopanib Hydrochloride in Treating Patients With Advanced Nonadipocytic Soft Tissue Sarcomas [Phase 1, Phase 2]
A Phase 1/2 trial evaluating nab-sirolimus in combination with pazopanib in advanced soft tissue sarcoma (including locally advanced and met…
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CLINICAL_TRIALS trial_result · 2024-03-06Clinical Trial Update: Adaptive Staged Stereotactic Body Radiation Therapy in Treating Patients With Spinal Metastases That Cannot Be Removed by Surgery [NA]
Clinical trial update for adaptive staged stereotactic body radiation therapy in patients with spinal metastases, completed with posted resu…
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma [Phase 2]
Phase 2 trial update for SHR-1210 plus Apatinib in soft tissue sarcoma has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2024-02-20Clinical Trial Update: Preoperative vs Postoperative IMRT for Extremity/Truncal STS [Phase 3]
Phase 3 trial comparing preoperative versus postoperative IMRT for extremity/truncal soft tissue sarcoma is active but not recruiting.
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CLINICAL_TRIALS trial_result · 2024-02-07Clinical Trial Update: Albumin-bound Paclitaxel Plus Camrelizumab for Advanced Soft Tissue Sarcoma. [Phase 2]
Phase 2 clinical trial investigating albumin-bound paclitaxel plus camrelizumab for advanced soft tissue sarcoma.