Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-12-26Clinical Trial Update: Study of LVGN3616 and LVGN6051±LVGN7409 in Combination With Nab-Paclitaxel or Bevacizumab and Cyclophosphamide in Metastatic Solid Tumors [Phase 1]
Phase 1 trial evaluating LVGN3616 and LVGN6051±LVGN7409 with nab-paclitaxel or bevacizumab and cyclophosphamide in various metastatic solid …
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Preoperative Moderately Fractionated IMRT for Locally Extremity or Trunk Sarcoma (SPARE-03) [Phase 2]
This update reports the completion of the SPARE-03 Phase 2 trial evaluating preoperative moderately fractionated IMRT for soft tissue sarcom…
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CLINICAL_TRIALS trial_result · 2025-12-11Clinical Trial Update: Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk Sarcoma （SPARE-02） [Phase 2]
Phase 2 trial assessing preoperative intensity-modulated radiotherapy with concurrent apatinib for localized soft tissue sarcoma of the extr…
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CLINICAL_TRIALS trial_result · 2025-12-08Clinical Trial Update: Pembrolizumab in Combination With Eftilagimod Alpha and Radiotherapy in Neoadjuvant Treatment of Patients With Soft Tissue Sarcoma - EFTISARC-NEO Trial [Phase 2]
Phase 2 neoadjuvant trial evaluating pembrolizumab with eftilagimod alpha and radiotherapy in soft tissue sarcoma; the study is currently ac…
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Retreatment With Intratumoral Diffusing Alpha Radiation Emitters [NA]
A completed clinical trial evaluating retreatment with intratumoral diffusing alpha radiation emitters for skin cancer, oral cavity mucosal …
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CLINICAL_TRIALS trial_result · 2025-12-02Clinical Trial Update: Dostarlimab for Locally Advanced or Metastatic Cancer (Non-colorectal/Non-endometrial) With Tumor dMMR/MSI [Phase 2]
Phase 2 trial evaluating dostarlimab for locally advanced or metastatic dMMR/MSI cancers excluding colorectal and endometrial, across multip…
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Nab-Paclitaxel and Gemcitabine for Recurrent/Refractory Sarcoma [Phase 2]
A Phase 2 trial of nab-paclitaxel plus gemcitabine for recurrent or refractory sarcoma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-12-01Clinical Trial Update: Prospective Study to Evaluate Patient Reported Outcomes (PRO) During Rechallenge With Trabectedin in Sarcoma Patients
A prospective study evaluating patient-reported outcomes during rechallenge with trabectedin in soft tissue sarcoma patients has been termin…
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CLINICAL_TRIALS trial_result · 2025-11-18Clinical Trial Update: Localized High-Risk Soft Tissue Sarcomas Of The Extremities And Trunk Wall In Adults: An Integrating Approach Comprising Standard Vs Histotype-Tailored Neoadjuvant Chemotherapy [Phase 3]
A Phase 3 trial comparing standard versus histotype-tailored neoadjuvant chemotherapy for localized high-risk soft tissue sarcomas of the ex…
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CLINICAL_TRIALS trial_result · 2025-11-06Clinical Trial Update: Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial [Phase 2]
This update reports on a Phase 2 pediatric MATCH trial evaluating selpercatinib for patients with activating RET gene alterations across adv…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of HFB301001 in Adult Patients With Advanced Solid Tumors [Phase 1]
The Phase 1 trial of HFB301001 in adults with advanced solid tumors has been terminated.
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CLINICAL_TRIALS trial_result · 2025-09-11Clinical Trial Update: Molecular Profiling to Improve Outcome of Patients in Cancer. A Pilot Study
A completed pilot study evaluating molecular profiling to guide cancer treatment and improve outcomes in patients with colorectal cancer or …
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CLINICAL_TRIALS trial_result · 2025-09-04Clinical Trial Update: Trabectedin Combined With Durvalumab in Patients With Advanced Pretreated Soft-tissue Sarcomas and Ovarian Carcinomas. [Phase 1]
This ClinicalTrials.gov entry reports a completed Phase 1 study evaluating the safety, tolerability, and preliminary activity of trabectedin…
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: A Phase II Study of Eribulin and Pembrolizumab in Soft Tissue Sarcomas [Phase 2]
A Phase II study evaluating the combination of eribulin and pembrolizumab in soft tissue sarcomas has completed, with results posted.
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CLINICAL_TRIALS trial_result · 2025-08-28Clinical Trial Update: Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas [Phase 1]
Phase 1 study of DCC-3014 in combination with Avelumab in patients with advanced or metastatic sarcoma has completed; no efficacy data is pr…
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: A Study of LY3039478 in Participants With Advanced or Metastatic Solid Tumors [Phase 1]
A Phase 1 study of LY3039478 in participants with advanced or metastatic solid tumors was terminated. Results were posted on 2025-08-21.
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CLINICAL_TRIALS trial_result · 2025-08-14Clinical Trial Update: Sequential Neoadjuvant Chemotherapy in Soft Tissue Sarcoma [Phase 2]
This update describes a Phase 2 clinical trial evaluating sequential neoadjuvant chemotherapy for soft tissue sarcoma conducted by Oslo Univ…
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CLINICAL_TRIALS trial_result · 2025-08-13Clinical Trial Update: Bintrafusp Alfa and Doxorubicin Hydrochloride in Treating Patients With Advanced Sarcoma [Phase 2]
Phase 2 study evaluating bintrafusp alfa in combination with doxorubicin hydrochloride for advanced or metastatic soft-tissue sarcoma is cur…
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: A Study of the Intratumoral Microdose Administration of PBA-0405 in Patients With Solid Tumors [EARLY_Phase 1]
Early-phase study update on intratumoral microdose administration of PBA-0405 in solid tumors; the trial status is completed.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Immunotherapy + Radiation in Resectable Soft Tissue Sarcoma [EARLY_Phase 1]
An early-phase clinical trial evaluating a combination of immunotherapy and radiation for resectable soft tissue sarcoma is currently active…
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CLINICAL_TRIALS trial_result · 2025-08-07Clinical Trial Update: Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds [NA]
Completed clinical trial evaluating incisional negative pressure wound therapy for preoperatively irradiated lower-extremity soft tissue sar…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Saving Limbs After Cancer: Blood Vessel and Soft Tissue Reconstruction Following Sarcoma Surgery in the Legs
A completed clinical trial examining blood vessel and soft tissue reconstruction after leg sarcoma surgery to help save limbs in patients wi…
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Study of DPPG2-TSL-DOX Combined With Hyperthermia in Soft Tissue Sarcoma [Phase 1]
A Phase 1 trial evaluating DPPG2-TSL-DOX in combination with hyperthermia for soft tissue sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2025-07-17Clinical Trial Update: Cabozantinib With Radiation Therapy for the Treatment of Sarcomas of the Extremities [Phase 1, Phase 2]
Phase 1/2 trial evaluating cabozantinib with radiation therapy for soft tissue sarcoma of the trunk and extremities was terminated, with res…
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CLINICAL_TRIALS trial_result · 2025-07-15Clinical Trial Update: Biopsy Needle Size in Soft Tissue Sarcoma [NA]
A completed clinical trial from Ankara City Hospital Bilkent assessing biopsy needle size in soft tissue sarcoma.