Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Update: Molecular Profiling of Advanced Soft-tissue Sarcomas [Phase 3]
Phase 3 trial assessing molecular profiling in advanced soft-tissue sarcomas has completed.
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: Efficacy and Safety of Envafolimab Plus Doxorubicin and Ifosfamide for Advanced Soft Tissue Sarcoma [Phase 2]
An ongoing Phase 2 trial is evaluating the combination of envafolimab with doxorubicin and ifosfamide for advanced soft tissue sarcoma, asse…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: MEK Inhibitor and a PDL1 Inhibitor Patients With Locally Advanced and/or Metastatic Soft Tissue Sarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating a MEK inhibitor in combination with a PD-L1 inhibitor for locally advanced or metastatic soft tissue s…
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Combination of Nivolumab Plus Relatlimab in Patients With Advanced or Metastatic Soft-tissue Sarcoma: a Proof-of-concept Randomized Phase II Study [Phase 2]
A completed Phase 2 randomized trial evaluating the combination of nivolumab and relatlimab in advanced or metastatic soft-tissue sarcoma.
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CLINICAL_TRIALS trial_result · 2026-04-21Clinical Trial Update: Lenvatinib and Pembrolizumab in People With Advanced Soft Tissue Sarcoma [Phase 2]
Phase 2 trial evaluating the combination of lenvatinib and pembrolizumab in adults with advanced soft tissue sarcoma; the study is currently…
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CLINICAL_TRIALS trial_result · 2026-04-20Clinical Trial Update: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma [Phase 1]
This clinical trial update describes a Phase 1 study assessing neoadjuvant ADI-PEG 20 plus ifosfamide and radiotherapy in soft tissue sarcom…
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CLINICAL_TRIALS trial_result · 2026-04-16Clinical Trial Update: Pembrolizumab With Intratumoral Injection of Clostridium Novyi-NT [Phase 1]
Phase 1 clinical trial evaluating pembrolizumab in combination with intratumoral injection of Clostridium novyi-NT across multiple cancer ty…
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) [Phase 2]
Phase 2 update from the Pediatric MATCH trial describes targeted therapies matched to tumor genetics in pediatric patients with relapsed or …
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CLINICAL_TRIALS trial_result · 2026-04-14Clinical Trial Update: Pharmacologic Interaction Between Ifosfamide and Aprepitant in Treated Patients With Soft Tissue Sarcoma [Phase 4]
Phase 4 trial assessing the pharmacologic interaction between ifosfamide and aprepitant in treated patients with soft tissue sarcoma; study …
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma [Phase 1]
Phase 1 trial evaluating the safety of low-dose pegylated liposomal doxorubicin in combination with peposertib for advanced sarcoma; current…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Hyperbaric Oxygen Therapy for Soft Tissue Sarcoma Pilot Study [Phase 4]
This ClinicalTrials.gov entry reports a Phase 4 pilot study evaluating hyperbaric oxygen therapy for soft tissue sarcoma, currently active b…
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CLINICAL_TRIALS trial_result · 2026-03-25Clinical Trial Update: Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial) [Phase 2]
Phase 2 pediatric MATCH trial evaluating IDH1-mutant tumors for response to ivosidenib; results for recurrent and refractory solid tumors, l…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: Phase II Study Evaluating Strategies of Lung Surveillance of Patients Operated of High Grade Soft Tissue Sarcoma [Phase 2]
Phase II study evaluating strategies for lung surveillance in patients operated for high-grade soft tissue sarcoma has been terminated. The …
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CLINICAL_TRIALS trial_result · 2026-03-13Clinical Trial Update: Phase II Study of Regorafenib in Metastatic Soft Tissue Sarcoma [Phase 2]
Phase II trial of regorafenib in metastatic soft tissue sarcoma has completed.
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Prospective Identification of Predictive Biomarkers of Trabectedin Efficacy in Non-L Soft-tissue Sarcoma Patients [NA]
Trial update reporting prospective identification of predictive biomarkers for trabectedin efficacy across non-liposarcoma soft tissue sarco…
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CLINICAL_TRIALS trial_result · 2026-03-06Clinical Trial Update: Combining Epigenetic And Immune Therapy to Beat Cancer. [Phase 2]
A Phase 2 trial from Institut Bergonié evaluating a combination of epigenetic therapy and immunotherapy in several advanced cancers has comp…
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CLINICAL_TRIALS trial_result · 2026-03-02Clinical Trial Update: Phase I Study Compound 451238 and Radiotherapy in Soft-tissue Sarcoma [Phase 1, Phase 2]
Phase I/II study of Compound 451238 with radiotherapy in soft-tissue sarcoma has completed; results have been posted.
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CLINICAL_TRIALS trial_result · 2026-02-25Clinical Trial Update: A Study of Olaparib With Concomitant Radiotherapy in Locally Advanced/Unresectable Soft-tissue Sarcoma [Phase 1]
Phase 1 study of olaparib with concomitant radiotherapy in locally advanced or unresectable soft-tissue sarcoma has been completed and resul…
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CLINICAL_TRIALS trial_result · 2026-02-19Clinical Trial Update: First-in-man Clinical Trial of CEB-01 PLGA Membrane in Recurrent or Locally Advanced Retroperitoneal Soft Tissue Sarcoma [Phase 1]
CEBIOTEX announced the completion of its first-in-man Phase 1 trial of CEB-01 PLGA Membrane for locally advanced or recurrent soft tissue sa…
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CLINICAL_TRIALS trial_result · 2026-02-18Clinical Trial Update: Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types [Phase 1, Phase 2]
This update reports a Phase 1/2 trial of atezolizumab plus tivozanib in several immunologically cold tumor types, with the study currently s…
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CLINICAL_TRIALS trial_result · 2026-02-04Clinical Trial Update: Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities [Phase 1]
A Phase 1 clinical trial evaluating the combination of gemcitabine and docetaxel with radiation for soft tissue sarcoma of the extremities h…
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CLINICAL_TRIALS trial_result · 2026-01-16Clinical Trial Update: Radiation Therapy Before Surgery for Localized, Resectable Soft Tissue Sarcoma of the Extremity and Superficial Trunk [Phase 2]
A Mayo Clinic phase 2 trial evaluating preoperative radiation therapy for localized, resectable soft tissue sarcoma of the extremities and s…
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CLINICAL_TRIALS trial_result · 2026-01-15Clinical Trial Update: Neoadjuvant Intralesional Injection of Talimogene Laherparepvec [Phase 2]
A Phase 2 neoadjuvant trial evaluating intralesional talimogene laherparepvec for soft tissue sarcoma is currently active but not recruiting…
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CLINICAL_TRIALS trial_result · 2026-01-07Clinical Trial Update: Tazemetostat in Combination With Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma [Phase 1]
A Phase 1 trial evaluating tazemetostat with doxorubicin as frontline therapy for advanced epithelioid sarcoma has been terminated.
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CLINICAL_TRIALS trial_result · 2026-01-06Clinical Trial Update: A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) Tumors [Phase 1, Phase 2]
This phase 1/2 clinical trial update reports results for selpercatinib in pediatric participants with advanced solid tumors and primary CNS …