Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas [Phase 1, Phase 2]
A clinical trial update describing a Phase 1/2 study of sequential infusion of CD146-targeted and HER2-targeted CAR T cells in patients with…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies [Phase 1, Phase 2]
SPEDOX-6, a single protein encapsulated doxorubicin, is being studied in Phase 1/2 trials for several advanced cancers and is currently recr…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling [Phase 1]
Phase 1 clinical trial evaluating ex vivo drug sensitivity testing and multi-omics profiling in pediatric cancers. Recruitment is ongoing ac…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Safety and Efficacy of DIT309 in Advanced Bone and Soft Tissue Sarcomas [Phase 1]
This document reports a Phase 1 clinical trial evaluating the safety and efficacy of DIT309 in advanced bone and soft tissue sarcomas, with …
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Selinexor Plus Gemcitabine in Selected Advanced Soft-tissue Sarcoma (SeliSarc) [Phase 2]
Phase 2 trial of Selinexor in combination with gemcitabine for selected advanced soft-tissue sarcoma is currently recruiting in the SeliSarc…
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Pre-operative RadiothErapy for Soft Tissue SarcOmas [NA]
This clinical trial update describes a pre-operative radiotherapy approach for soft tissue sarcoma, with the study currently active but not …
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa. [Phase 2]
A Phase 2 clinical trial evaluating pre-operative hypofractionated radiation therapy in elderly or frail patients with limb or trunk soft ti…
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CLINICAL_TRIALS research · 2025-05-30Clinical Trial Update: Spatially Fractionated Radiotherapy Versus Conventional Radiotherapy in the Treatment of Soft Tissue Sarcoma [NA]
A clinical trial is comparing spatially fractionated radiotherapy with conventional radiotherapy for soft tissue sarcoma and is currently re…
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CLINICAL_TRIALS research · 2025-05-28Clinical Trial Update: Prehabilitation in Childhood Soft Tissue or Bone Sarcomas [NA]
A pediatric prehabilitation study for childhood soft tissue sarcoma and bone tumors is currently enrolling by invitation at the Technical Un…
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma [NA]
A clinical trial update describes a study evaluating whether early psychiatric referral improves mental health and quality of life in people…
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CLINICAL_TRIALS research · 2025-05-13Clinical Trial Update: Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial is evaluating the combination of brachytherapy using iodine-125 seeds with the PARP inhibitor fluzoparib for advanc…
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: Gemcitabine Plus Ascorbate for Sarcoma in Adults (Pilot) [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating gemcitabine plus high-dose ascorbate for sarcoma in adults is active but not recruiting.
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Collecting and Storing Tissue From Young Patients With Cancer
A completed clinical trial update from the Children’s Oncology Group describing the collection and storage of tissue from pediatric cancer p…
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CLINICAL_TRIALS research · 2025-04-29Clinical Trial Update: APX005M and Doxorubicin in Advanced Sarcoma [Phase 2]
A Phase 2 clinical trial evaluating APX005M in combination with doxorubicin for advanced soft tissue sarcoma is currently active but not rec…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: tTF-NGR Randomized Study - STS [Phase 3]
Phase 3 randomized study evaluating tTF-NGR for soft tissue sarcoma is currently recruiting.
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CLINICAL_TRIALS research · 2025-03-28Clinical Trial Update: Hypofractionated Radiotherapy Followed by Surgical Resection in the Treatment of Soft Tissue Sarcomas [Phase 2]
This ClinicalTrials.gov entry describes a Phase 2 trial evaluating hypofractionated radiotherapy followed by surgical resection for soft tis…
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CLINICAL_TRIALS research · 2025-03-25Clinical Trial Update: Comparison of Oral Cyclophosphamide vs Doxorubicin in ≥65 Years Old Advanced or Metastatic Soft Tissue Sarcoma Patients [Phase 3]
Phase 3 trial comparing oral cyclophosphamide versus doxorubicin in patients aged 65 and older with advanced or metastatic soft tissue sarco…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor [Phase 1, Phase 2]
Multicohort Phase 1/2 clinical trial evaluating PM14 as monotherapy and in combination with radiotherapy for soft tissue sarcoma and other s…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Observational Study, for Quality Assessment, of Sarcoma in European and Latin American Multidisciplinary NETWORK
An observational quality-assessment study of sarcoma being conducted across European and Latin American multidisciplinary networks; recruitm…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: SAVE Studie- SArcoma Surgery With Vacuum Enhanced Wound Treatment Randomised Study to Evaluate the Wound Management in Sarcoma Surgery [NA]
A clinical trial evaluating vacuum-enhanced wound treatment for sarcoma surgery is currently recruiting at Universitätsklinikum Hamburg-Eppe…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Soft Tissue Sarcoma: Motor Performance, Robotic Rehabilitation, Nutrition, and Quality of Life [NA]
This clinical trial update reports a study on soft tissue sarcoma evaluating motor performance, robotic rehabilitation, nutrition, and quali…
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CLINICAL_TRIALS research · 2025-02-27Clinical Trial Update: Umbilical Cord Blood NK Cell Therapy for High-Risk Pediatric Soft Tissue Sarcoma: Efficacy and Safety Study [NA]
This clinical trial update reports on a study of umbilical cord blood-derived natural killer (NK) cell therapy for high-risk pediatric soft …
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: SAINT:Trabectedin, Ipilimumab and Nivolumab for Previously Treated Advanced Soft Tissue Sarcoma [Phase 1, Phase 2]
A Phase 1/2 clinical trial update evaluating the triple combo of trabectedin, ipilimumab, and nivolumab in previously treated advanced or me…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Evaluation of AL3818 in Combination With Nivolumab in Solid Tumors [Phase 1, Phase 2]
Clinical trial update on a Phase 1/2 study evaluating AL3818 in combination with nivolumab for solid tumors; the trial is currently not recr…
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Metronomic Trabectedin, Gemcitabine, and Dacarbazine for Soft Tissue Sarcoma [Phase 2]
A Phase 2 clinical trial update evaluating metronomic dosing of a three-drug combination (trabectedin, gemcitabine, and dacarbazine) for lei…