Soft Tissue Sarcoma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: Colorectal Resections in Patients With Retroperitoneal Sarcoma
This clinical trial update describes a study on colorectal resections in patients with retroperitoneal soft tissue sarcoma, which is current…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Molecular Profiling of Advanced Soft-tissue Sarcomas [Phase 3]
A Phase 3 trial examining molecular profiling for advanced soft-tissue sarcomas is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Preoperative IMRT With Concurrent Anlotinib for Localised Extremity or Trunk Sarcoma （SPARE-01） [Phase 2]
Phase 2 clinical trial evaluating preoperative intensity-modulated radiotherapy with concurrent Anlotinib for localized soft tissue sarcoma …
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: Preoperative Ultra-hypofractionated Radiotherapy Followed by Surgery for Retroperitoneal Sarcoma (FUSION-01) [NA]
This entry reports the ongoing FUSION-01 trial evaluating preoperative ultra-hypofractionated radiotherapy followed by surgery for retroperi…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Minibeam Radiation Therapy With Tungsten Slit Collimator for the Treatment of Recurrent or Metastatic Skin or Soft Tissue Tumors, MBRT1 Trial [NA]
The MBRT1 trial is evaluating minibeam radiation therapy with a tungsten slit collimator for recurrent or metastatic skin and soft tissue tu…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Feasibility Trial of Preoperative 5-Day Hypofractionated Radiotherapy for Primary Soft Tissue Sarcoma [NA]
This is a feasibility study evaluating a preoperative 5-day hypofractionated radiotherapy regimen for primary soft tissue sarcoma; the trial…
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Habitat Escalated Adaptive Therapy (HEAT), With Neoadjuvant Radiation for Soft Tissue Sarcoma [Phase 2]
Phase 2 clinical trial update for Habitat Escalated Adaptive Therapy (HEAT) with neoadjuvant radiation in soft tissue sarcoma; the study is …
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Fluorescence-Guided Optimization of Sarcoma Margins [NA]
A clinical trial evaluating fluorescence-guided techniques to optimize sarcoma surgical margins. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study. [NA]
This clinical trial update reports on a biomarker study investigating the CINSARC gene expression signature and its correlation with chemoth…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Preventive Application of Single-use Negative Pressure Wound Therapy (sNPWT) in the Postoperative Course of Radiotreatated Limb Sarcoma Surgery [NA]
This clinical trial update indicates that a study is currently recruiting to evaluate the preventive use of single-use negative pressure wou…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Alpha Radiation Emitters Device (DaRT) for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia. [NA]
A clinical trial evaluating the Diffusing Alpha-emitters Radiation Therapy (DaRT) device for treating skin cancer, oral mucosal cancer, and …
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CLINICAL_TRIALS research · 2025-12-01Clinical Trial Update: BOLD-100 Plus Doxorubicin in Advanced Soft Tissue Sarcomas [Phase 1]
Phase 1 clinical trial evaluating the combination of BOLD-100 with doxorubicin in advanced soft tissue sarcoma; study status is not yet recr…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: In Vivo Lung Perfusion for Pulmonary Metastases of Sarcoma [Phase 1]
Phase 1 clinical trial update on in vivo lung perfusion for sarcoma with pulmonary metastases; the study is currently recruiting.
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Prospective Phase I/II Study Evaluating the Safety and Efficacy of Preoperative Carbon Ion Radiotherapy in Patients With Soft Tissue Sarcoma : The SARCOMA-01 Trial by the Severance sARCOma Multidisciplinary Team [NA]
A prospective Phase I/II clinical trial evaluating preoperative carbon ion radiotherapy for soft tissue sarcoma, sponsored by Yonsei Univers…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations [Phase 2, Phase 3]
An ongoing DETERMINE trial (arm 06) investigates capmatinib for MET-dysregulated cancers, with Phase 2/3 testing and current recruitment.
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CLINICAL_TRIALS research · 2025-11-21Clinical Trial Update: LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas [Phase 2]
Phase 2 study of LN-145 (LN-145-S1) in relapsed or refractory ovarian cancer, triple-negative breast cancer, anaplastic thyroid cancer, oste…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults [Phase 1]
Phase 1 clinical trial update describing B7H3-targeted CAR T-cell therapy for recurrent/refractory pediatric solid tumors, including several…
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CLINICAL_TRIALS research · 2025-11-20Clinical Trial Update: SATURN-STS: Phase II Study of Neoadjuvant Atezolizumab With Doxorubicin, Concurrent Atezolizumab With Pre-operative Radiation Therapy and Adjuvant Atezolizumab in Patients With High-risk Surgically Resectable Extremity and Truncal Soft Tissue Sarcoma [Phase 2]
A Phase II trial evaluating neoadjuvant atezolizumab with doxorubicin, concurrent atezolizumab with pre-operative radiation therapy, and adj…
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CLINICAL_TRIALS research · 2025-11-19Clinical Trial Update: QL1706 in the Treatment of Advanced Bone and Soft Tissue Sarcoma [Phase 2]
An update on an ongoing Phase 2 trial evaluating QL1706 for advanced bone cancer and soft tissue sarcoma, currently recruiting.
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma [Phase 2]
A Phase 2 trial evaluating cabozantinib in combination with PD-1 and CTLA-4 inhibitors for metastatic soft tissue sarcoma; the study is curr…
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Study of Aerosol Gemcitabine in Patients With Solid Tumors and Pulmonary Metastases [Phase 1]
Phase 1 study evaluating aerosolized gemcitabine for treatment of various solid tumors, including those with pulmonary metastases; recruitme…
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CLINICAL_TRIALS research · 2025-10-22Clinical Trial Update: Microwave Ablation or Wedge Resection for the Treatment of Lung, Sarcoma and Colorectal Lesions, ALLUME Study
The ALLUME Study is evaluating microwave ablation versus wedge resection for treatment of lung, sarcoma, and colorectal lesions, including v…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A First-In-Human Phase 1 Trial of T-Cell Membrane-Anchored Tumor Targeted Il12 (Attil12)- T-Cell Therapy in Subjects With Advanced/Metastatic Soft Tissue and Bone Sarcoma [Phase 1]
First-in-human Phase 1 trial evaluating Attil12, a T-cell therapy with membrane-anchored IL-12, in patients with advanced soft tissue and bo…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study of Niraparib in People With Soft Tissue Sarcoma Who Have Changes in Their Tumor DNA [Phase 2]
A Phase 2 trial evaluating niraparib in patients with soft tissue sarcoma who harbor tumor DNA alterations; the study is currently active bu…
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CLINICAL_TRIALS research · 2025-10-20Clinical Trial Update: A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma [Phase 2]
A Phase 2 study evaluating the combination of Etrumadenant and Zimberelimab in Dedifferentiated liposarcoma; the trial is currently active b…