Smoldering Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma [Phase 2]
A Phase 2 study evaluating three dosing schedules of daratumumab in participants with smoldering multiple myeloma has completed and posted r…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Real-world Study in Participants With Smoldering Multiple Myeloma
A completed real-world study evaluating outcomes in participants with smoldering multiple myeloma, sponsored by Janssen-Cilag Ltd.
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma [Phase 2]
Phase II study of the CD38 antibody daratumumab in high-risk monoclonal gammopathy of undetermined significance (MGUS) and low-risk smolderi…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM) [Phase 3]
A Phase 3 trial comparing Linvoseltamab to Daratumumab in high-risk smoldering multiple myeloma is not yet recruiting.
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CLINICAL_TRIALS trial_result · 2026-02-09Clinical Trial Update: Investigation of Metformin for the Prevention of Progression of Precursor Multiple Myeloma [Phase 2]
A Phase 2 clinical trial evaluating whether metformin can prevent progression from precursor conditions to active multiple myeloma.
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CLINICAL_TRIALS trial_result · 2026-01-05Clinical Trial Update: Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma [EARLY_Phase 1]
Early-phase 1 clinical trial update evaluating leflunomide for high-risk smoldering multiple myeloma; the study is currently active but not …
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma [Phase 3]
Phase 3 clinical trial update reporting results for subcutaneous daratumumab versus active monitoring in participants with high-risk smolder…
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CLINICAL_TRIALS trial_result · 2025-12-23Clinical Trial Update: A Study of Subcutaneous Daratumumab Versus Active Monitoring in Participants With High-Risk Smoldering Multiple Myeloma [Phase 3]
Phase 3 trial comparing subcutaneous daratumumab to active monitoring in high-risk smoldering multiple myeloma has completed with results po…
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CLINICAL_TRIALS trial_result · 2025-12-19Clinical Trial Update: Personalized Vaccine in Treating Patients With Smoldering Multiple Myeloma [EARLY_Phase 1]
An early-phase (Phase 1) trial evaluating a personalized vaccine for patients with smoldering multiple myeloma has completed. The record ind…
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CLINICAL_TRIALS trial_result · 2025-12-12Clinical Trial Update: Isatuximab in Combination With Lenalidomide and Dexamethasone in High-risk Smoldering Multiple Myeloma [Phase 3]
Phase 3 trial evaluating isatuximab in combination with lenalidomide and dexamethasone for high-risk smoldering multiple myeloma; currently …
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CLINICAL_TRIALS trial_result · 2025-08-20Clinical Trial Update: Immunomodulatory Drugs (Lenalidomide With or Without Pomalidomide) in Combination With a Corticosteroid Drug (Dexamethasone) for the Treatment of Multiple Myeloma [Phase 2]
Phase 2 trial evaluating lenalidomide with or without pomalidomide in combination with dexamethasone for multiple myeloma; the study was ter…
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CLINICAL_TRIALS trial_result · 2025-08-19Clinical Trial Update: The Development and Pilot Testing of a New MR Imaging Protocol to Quantify Myeloma Disease Burden and Bone Loss
This clinical trial update reports the development and pilot testing of a new magnetic resonance imaging protocol to quantify multiple myelo…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: Trial of Combination of Ixazomib and Lenalidomide and Dexamethasone in Smoldering Multiple Myeloma [Phase 2]
Phase 2 trial evaluating ixazomib, lenalidomide, and dexamethasone in smoldering multiple myeloma has completed and posted results.
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) [NA]
A Memorial Sloan Kettering Cancer Center trial is evaluating a plant-based diet in people with Monoclonal Gammopathy of Undetermined Signifi…
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Denosumab for High Risk SMM and SLiM CRAB Positive, Early Myeloma Patients [Phase 2]
Phase 2 study of denosumab in high-risk smoldering multiple myeloma and SLiM-CRAB positive early multiple myeloma patients has completed.
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CLINICAL_TRIALS trial_result · 2025-02-10Clinical Trial Update: Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma [Phase 2]
Phase 2 clinical trial evaluating selinexor for intermediate- and high-risk smoldering multiple myeloma is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Screening to Improve Survival in AL Amyloidosis
The clinical trial update reports completion of a screening-based study aimed at improving survival in light-chain (AL) amyloidosis. The stu…
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CLINICAL_TRIALS trial_result · 2024-05-13Clinical Trial Update: Ixazomib (MLN9708) and Dexamethasone in High Risk Smoldering Multiple Myeloma: A Clinical and Correlative Pilot Study [Phase 1]
Phase 1 pilot study evaluating ixazomib with dexamethasone in patients with high-risk smoldering myeloma and multiple myeloma; the trial has…
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CLINICAL_TRIALS trial_result · 2023-12-12Clinical Trial Update: Aggressive Smoldering Curative Approach Evaluating Novel Therapies and Transplant [Phase 2]
Phase 2 clinical trial update investigating aggressive curative approach with novel therapies and transplant for smoldering multiple myeloma…
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CLINICAL_TRIALS trial_result · 2023-06-13Clinical Trial Update: A Phase II Trial If Nivolumab, Lenalidomide and Dexamethasone in High Risk Smoldering Myeloma [Phase 2]
Phase II trial of nivolumab, lenalidomide, and dexamethasone in high-risk smoldering multiple myeloma has completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-06-09Clinical Trial Update: E-PRISM: Phase II Trial of Elotuzumab Lenalidomide and Dexamethasone in High-Risk Smoldering Multiple Myeloma [Phase 2]
Phase II trial (E-PRISM) evaluating elotuzumab, lenalidomide, and dexamethasone in high-risk smoldering multiple myeloma has completed with …
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CLINICAL_TRIALS trial_result · 2023-02-15Clinical Trial Update: Denosumab for Smoldering Multiple Myeloma [Phase 2]
Phase 2 clinical trial of denosumab in smoldering multiple myeloma has completed and results were posted in February 2023.
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CLINICAL_TRIALS trial_result · 2022-09-13Clinical Trial Update: Carfilzomib, Lenalidomide, and Dexamethasone for Smoldering Multiple Myeloma [Phase 2]
Phase 2 trial evaluating Carfilzomib, Lenalidomide, and Dexamethasone in Smoldering Multiple Myeloma has completed and results have been pos…
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CLINICAL_TRIALS trial_result · 2022-09-10Clinical Trial Update: Carfilzomib in Treatment Patients Under 65 Years With High Risk Smoldering Multiple Myeloma [Phase 2]
Phase 2 trial update evaluating carfilzomib in treatment patients under 65 with high-risk smoldering multiple myeloma.
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CLINICAL_TRIALS trial_result · 2021-05-18Clinical Trial Update: Lenalidomide or Observation in Treating Patients With Asymptomatic High-Risk Smoldering Multiple Myeloma [Phase 3]
A Phase 3 trial compared lenalidomide to observation in asymptomatic high-risk smoldering multiple myeloma; results were posted on May 18, 2…