Smoldering Multiple Myeloma
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: A Study to Evaluate 3 Dose Schedules of Daratumumab in Participants With Smoldering Multiple Myeloma [Phase 2]
A Phase 2 study evaluating three dosing schedules of daratumumab in participants with smoldering multiple myeloma has completed and posted r…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Integrative Multi-omics Analysis to Predict Monoclonal Gammopathies Clinical Evolution
This clinical trial update describes a study using integrative multi-omics analysis to predict the clinical evolution of monoclonal gammopat…
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Observational Prospective Research Study In Monoclonal Gammopathies leadINg to Myeloma
An observational prospective study at MD Anderson Cancer Center investigating monoclonal gammopathies that progress to myeloma; the trial is…
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CLINICAL_TRIALS research · 2026-04-17Clinical Trial Update: Iberdomide Alone or in Combination With Dexamethasone for the Treatment of Intermediate- or High-Risk Smoldering Multiple Myeloma [Phase 2]
Phase 2 trial evaluating iberdomide alone or in combination with dexamethasone for intermediate- or high-risk smoldering multiple myeloma is…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM) [NA]
A clinical trial protocol comparing a plant-based diet with supplements and a placebo in people with Monoclonal Gammopathy of Undetermined S…
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CLINICAL_TRIALS research · 2026-04-16Clinical Trial Update: Promoting Diagnosis and Management of AL in Italy (ProDigALIty)
A clinical trial in Italy (ProDigALIty) aims to promote diagnosis and management of AL amyloidosis and related plasma cell disorders and is …
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Quality of Life in Patients With Asymptomatic Monoclonal Gammopathies
This clinical trial update notes a study recruiting to assess quality of life in patients with asymptomatic monoclonal gammopathies, includi…
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: Isatuximab With or Without Lenalidomide in Patients With High Risk Smoldering Multiple Myeloma (ISAMAR) [Phase 2]
A Phase 2 clinical trial update on isatuximab with or without lenalidomide for patients at high risk of progression from smoldering multiple…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: A Proof-of-Concept Trial to Study the Safety and Activity of Linvoseltamab in Adult Participants With Smoldering Multiple Myeloma at High Risk of Developing Multiple Myeloma [Phase 2]
A Phase 2 proof-of-concept trial is evaluating the safety and activity of linvoseltamab in adults with smoldering multiple myeloma at high r…
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CLINICAL_TRIALS trial_result · 2026-04-13Clinical Trial Update: A Real-world Study in Participants With Smoldering Multiple Myeloma
A completed real-world study evaluating outcomes in participants with smoldering multiple myeloma, sponsored by Janssen-Cilag Ltd.
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Two Biologically and Clinically Distinct Entities: Progressive Versus Stable Multiple Myeloma (MM) Precursor Conditions
The document provides a clinical trial update from the University of Miami describing two distinct precursor states of multiple myeloma—prog…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma [Phase 2]
Phase 2 proof-of-concept trial assessing Linvoseltamab in adults with high-risk Monoclonal Gammopathy of Undetermined Significance or non-hi…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: Lenalidomide, and Dexamethasone With or Without Daratumumab in Treating Patients With High-Risk Smoldering Myeloma [Phase 3]
A Phase 3 clinical trial evaluating lenalidomide and dexamethasone with or without daratumumab in patients with high-risk smoldering multipl…
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CLINICAL_TRIALS research · 2026-04-03Clinical Trial Update: A Prospective Multicenter Study of the Effects of Plant-based Diets on Gut Microbiome and Derived Metabolites in Patients Affected by Smoldering Multiple Myeloma [NA]
A prospective multicenter trial is evaluating the effects of plant-based diets on the gut microbiome and derived metabolites in patients wit…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Subcutaneous Daratumumab, Once Weekly Carfilzomib, and Dexamethasone (DKd) in Patients With High-Risk Smoldering Multiple Myeloma [Phase 2]
This Phase 2 trial update describes subcutaneous daratumumab, once-weekly carfilzomib, and dexamethasone (DKd) in patients with high-risk sm…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Questionnaire and Tissue Banking For Multiple Myeloma, Waldenstrom Macroglobulinemia and Related Disorders
A clinical trial registry update from Dana-Farber Cancer Institute notes a study involving questionnaires and tissue banking for multiple my…
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CLINICAL_TRIALS trial_result · 2026-03-27Clinical Trial Update: Phase II Study of the CD38 Antibody Daratumumab in Patients With High-Risk MGUS and Low-Risk Smoldering Multiple Myeloma [Phase 2]
Phase II study of the CD38 antibody daratumumab in high-risk monoclonal gammopathy of undetermined significance (MGUS) and low-risk smolderi…
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CLINICAL_TRIALS research · 2026-03-23Clinical Trial Update: Evaluating the Impact of a 12-month Multi-Modal Lifestyle Management Intervention on Disease Relevant Biomarkers [NA]
A clinical trial is evaluating a 12-month multimodal lifestyle management program and its effect on disease-relevant biomarkers in individua…
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CLINICAL_TRIALS trial_result · 2026-03-16Clinical Trial Update: A Study to Compare Linvoseltamab and Daratumumab Treatment in High-Risk Smoldering Multiple Myeloma (HR-SMM) [Phase 3]
A Phase 3 trial comparing Linvoseltamab to Daratumumab in high-risk smoldering multiple myeloma is not yet recruiting.
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CLINICAL_TRIALS research · 2026-03-13Clinical Trial Update: A Study of PVX-410, a Cancer Vaccine, and Citarinostat +/- Lenalidomide for Smoldering MM [Phase 1]
Phase 1 study evaluating PVX-410 cancer vaccine with citarinostat, with or without lenalidomide, in patients with smoldering multiple myelom…
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CLINICAL_TRIALS research · 2026-03-12Clinical Trial Update: CAR- PRISM (PRecision Intervention Smoldering Myeloma) [Phase 2]
Phase 2 trial update for CAR-PRISM, a cellular therapy for multiple myeloma and smoldering multiple myeloma, sponsored by Dana-Farber Cancer…
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CLINICAL_TRIALS research · 2026-03-05Clinical Trial Update: Leflunomide for the Treatment of High-Risk Smoldering Multiple Myeloma in African-American and European-American Patients [Phase 2]
Phase 2 clinical trial evaluating leflunomide for high-risk smoldering multiple myeloma in African-American and European-American patients; …
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CLINICAL_TRIALS research · 2026-03-03Clinical Trial Update: FAST-M: Prolonged Overnight Fasting and Mediterranean Dietary Intervention for Patients With Multiple Myeloma or Its Precursor Disease [NA]
This entry describes the FAST-M trial evaluating prolonged overnight fasting with a Mediterranean diet for patients with multiple myeloma or…
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CLINICAL_TRIALS research · 2026-02-23Clinical Trial Update: Teclistamab in Combination With Daratumumab for High-Risk Smoldering Myeloma: A Clinical and Correlative Phase 2 Immuno-Oncology Study (the REVIVE Study) [Phase 2]
This is a Phase 2 clinical trial update (REVIVE) evaluating teclistamab in combination with daratumumab for high-risk smoldering/wholedown m…
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CLINICAL_TRIALS research · 2026-02-17Clinical Trial Update: Smoldering Myeloma High-Risk Patient Observation and Longitudinal Insight Trial
The document updates on a University of Utah–sponsored clinical trial evaluating high-risk smoldering multiple myeloma with long-term observ…