Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma [Phase 1, Phase 2]
Clinical trial update for VMD-928 as a monotherapy and in combination with pembrolizumab to treat TrkA overexpression-driven solid tumors or…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: A Study to Test Different Doses of BI 764532 in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3 [Phase 1]
Phase 1 study evaluating different doses of BI 764532 in DLL3-positive small cell lung cancer and other neuroendocrine tumors; the trial is …
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CLINICAL_TRIALS research · 2025-12-05Clinical Trial Update: Post-line Treatment With Teniposide for c-Myc-driven Extensive-stage Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial update evaluating post-line treatment with teniposide for c-Myc-driven extensive-stage small cell lung cancer; recrui…
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Study of GV20-0251 in Participants With Solid Tumor Malignancies [Phase 1, Phase 2]
GV20 Therapeutics is evaluating GV20-0251 in a Phase 1/2 trial for adults with various solid tumors, and the study is currently recruiting. …
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CLINICAL_TRIALS research · 2025-12-03Clinical Trial Update: Olvi-Vec Combined With Platinum Plus Etoposide Therapy in Patients With Late Phase SCLC [Phase 1, Phase 2]
A clinical trial update indicates an ongoing Phase 1/Phase 2 study of Olvi-Vec in combination with platinum-based chemotherapy and etoposide…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Targeted Therapy With CDK4/6 Inhibitors in Chemo-Refractory, Rb Wild-Type Extensive SCLC [Phase 2]
Phase 2 clinical trial assessing CDK4/6 inhibitors for chemo-refractory, RB wild-type extensive small-cell lung cancer. The study also inclu…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: A Phase II Clinical Study to Evaluate HLX43 in Combination With Serplulimab in Subjects With Advanced Lung Cancer [Phase 2]
Phase II clinical study to evaluate HLX43 in combination with Serplulimab for advanced lung cancer; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: 7T Brain MRI Scan for Micro-brain Metastasis (microBM) Detection for Patients With Small-cell Lung Cancer (SCLC), Who Decline Prophylactic Cranial Irradiation (PCI)
A clinical trial evaluating the use of 7T brain MRI to detect micro-brain metastases in small-cell lung cancer patients who decline prophyla…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Safety and Efficacy of Radiotherapy Combined With Immunochemotherapy in Pre-treated SCLC Patients With Liver Metastases [Phase 2]
A Phase 2 trial evaluating radiotherapy combined with immunochemotherapy in pre-treated small cell lung cancer patients with liver metastase…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Study Investigating Tarlatamab (AMG 757) in Patients With Metastatic/Locally Advanced Small-Cell Lung Cancer (SCLC) and Other Poorly Differentiated Neuroendocrine Carcinomas (NECs), With Biomarker Analysis to Characterize Response/Resistance (UNLOCK TARLATAMAB) [Phase 2]
Phase 2 clinical trial update assessing tarlatamab (AMG 757) in metastatic/locally advanced small-cell lung cancer and other poorly differen…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: This Study is an Open-lable, Phase I Study to Evaluate the Safety, Feasibility, Cytokinetics, and Preliminary Efficacy of GC511B in DLL3+ Relapsed/Refractory Small Cell Lung Cancer. [Phase 1]
This is an open-label Phase I study evaluating the safety, feasibility, cytokinetics, and preliminary efficacy of GC511B in DLL3-positive re…
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: Long-Terms Responders in Metastatic Lung Cancer: Better Understanding for Better Management (Lungevity Study)
Clinical trial update describing a study on long-term responders in metastatic lung cancer to improve management, currently recruiting.
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CLINICAL_TRIALS research · 2025-11-25Clinical Trial Update: [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck Cancers [Phase 1]
Phase 1 trial evaluating the radiopharmaceutical [212Pb]VMT-Alpha-NET across multiple somatostatin receptor–positive cancers, with recruitme…
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CLINICAL_TRIALS research · 2025-11-24Clinical Trial Update: TC-D101 Cell Therapy for Patients With DLL3-Positive SCLC [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating TC-D101, a DLL3-targeted CAR-T cell therapy, for DLL3-positive small cell lung cancer is currentl…
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CLINICAL_TRIALS trial_result · 2025-11-21Clinical Trial Update: Supportive Care Intervention (ROAR-LCT) for Patients With Stage IIIA, IIIB, and IV Lung Cancer, ROAR-LCT Trial [NA]
Completed clinical trial evaluating a supportive care intervention (ROAR-LCT) for patients with advanced non-small cell lung cancer and smal…
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CLINICAL_TRIALS trial_result · 2025-11-19Clinical Trial Update: Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) [Phase 1]
Amgen's Phase 1 study is assessing safety, tolerability, and pharmacokinetics of Tarlatamab in adults with small cell lung cancer, with the …
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer [Phase 1, Phase 2]
A dose-escalation Phase 1 study followed by expansion Phase 2 trial of ZG006 in advanced small cell lung cancer and neuroendocrine cancer, c…
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CLINICAL_TRIALS research · 2025-11-17Clinical Trial Update: A Study of YL201 and Ivonescimab (AK112) in Advanced Solid Tumors [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating YL201 in combination with Ivonescimab (AK112) for advanced solid tumors, including non-small cell lung…
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CLINICAL_TRIALS research · 2025-11-12Clinical Trial Update: Study of NMS-03305293 in Adult Patient With Relapsed Small Cell Lung Cancer [Phase 1]
This document announces a Phase 1 study of NMS-03305293 for adults with relapsed small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS research · 2025-11-10Clinical Trial Update: Personalized Radiotherapy for Individualized Treatment Strategies and Monitoring (PRISM) [Phase 1]
Phase 1 trial PRISM investigates personalized radiotherapy for extensive-stage small cell lung cancer with brain metastases; recruitment is …
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CLINICAL_TRIALS research · 2025-10-31Clinical Trial Update: Palliative Radiotherapy With Lurbinectedin in Patients With Extensive Stage Small Cell Lung Cancer [Phase 1]
A Phase 1 trial at Emory University is evaluating palliative radiotherapy in combination with lurbinectedin for extensive-stage small cell l…
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CLINICAL_TRIALS trial_result · 2025-10-29Clinical Trial Update: Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Participants With Untreated Extensive-Stage Small Cell Lung Cancer [Phase 3]
Phase 3 trial evaluating whether adding tiragolumab to atezolizumab plus carboplatin and etoposide improves outcomes in untreated extensive-…
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CLINICAL_TRIALS research · 2025-10-29Clinical Trial Update: Biology of Young Lung Cancer Study: The YOUNG LUNG Study
The YOUNG LUNG Study is currently recruiting, focusing on the biology of lung cancer in younger patients.
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CLINICAL_TRIALS research · 2025-10-28Clinical Trial Update: A Study to Test How BI 764532 is Taken up by Tumours in People With Small-cell Lung Cancer or Neuroendocrine Cancer [Phase 1]
Phase 1 study to evaluate how the investigational cancer drug BI 764532 is taken up by tumors in people with small cell lung cancer or neuro…
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CLINICAL_TRIALS trial_result · 2025-10-22Clinical Trial Update: A Study of Atezolizumab Plus Carboplatin and Etoposide With or Without Tiragolumab in Patients With Untreated Extensive-Stage Small Cell Lung Cancer [Phase 3]
Phase 3 study of atezolizumab plus carboplatin and etoposide with or without tiragolumab in untreated extensive-stage small cell lung cancer…