Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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EMA approval · 2026-07-01EMA Authorised: Hetronifly (serplulimab) — Accord Healthcare S.L.U.
European Medicines Agency authorises Hetronifly (serplulimab) for multiple indications including small cell lung cancer, non-small cell lung…
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CLINICAL_TRIALS trial_result · 2026-07-01Clinical Trial Results: Efficacy and Safety of Pembrolizumab Plus Investigational Agents in Combination With Chemotherapy as First-Line Treatment in Extensive-Stage Small Cell Lung Cancer (ES-SCLC) (MK-3475-B99/ KEYNOTE-B99) [Phase 2]
Phase 2 trial evaluating pembrolizumab combined with chemotherapy and investigational agents as first-line treatment for extensive-stage sma…
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CLINICAL_TRIALS trial_result · 2026-06-18Clinical Trial Results: GD2-SADA:177Lu-DOTA Complex in Patients With Solid Tumors Known to Express GD2 [Phase 1]
Phase 1 trial of GD2-SADA:177Lu-DOTA complex for GD2-expressing solid tumors was terminated; results posted.
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Update: Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC) [Phase 3]
Phase 3 trial evaluating tarlatamab after chemoradiotherapy in limited-stage small cell lung cancer is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study Comparing Tarlatamab, Durvalumab, Carboplatin, and Etoposide Versus Durvalumab, Carboplatin, and Etoposide in First-line Extensive Stage Small-Cell Lung Cancer (ES-SCLC) [Phase 3]
A Phase 3 trial in first-line extensive-stage small-cell lung cancer compares Tarlatamab plus Durvalumab with Carboplatin and Etoposide to D…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Tissue Procurement and Natural History Study of People With Non-Small Cell Lung Cancer, Small Cell Lung Cancer, Extrapulmonary Small Cell Cancer, Pulmonary Neuroendocrine Tumors, and Thymic Epithelial Tumors
This clinical trial update from the National Cancer Institute describes tissue procurement and a natural history study enrolling people with…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Clinical Study for the Safety and Efficacy of BL0020 Injection in Combination With Toripalimab Injection in Patients With Recurrent Extensive-Stage Small Cell Lung Cancer [Phase 1]
A Phase 1 clinical trial evaluating BL0020 in combination with toripalimab for recurrent extensive-stage small cell lung cancer; the study s…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Comprehensive Oncogenomic Mapping and Exploration in Thoracic and Head & Neck Oncology
A not-yet-recruiting trial from University of Kansas Medical Center aims to comprehensively map oncogenomic profiles in thoracic and head-an…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: Study of 225Ac-ABD147 to Establish Optimal Dose in Patients With SCLC and LCNEC of the Lung That Previously Received Platinum-based Chemotherapy [Phase 1]
Ongoing Phase 1 trial update for 225Ac-ABD147 to establish the optimal dose in patients with small-cell lung cancer and large cell neuroendo…
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CLINICAL_TRIALS research · 2026-04-24Clinical Trial Update: A Study of DXC014 in Patients With Advanced Solid Tumors. [Phase 1]
Phase 1 study of the investigational drug DXC014 in advanced solid tumors is currently recruiting. It includes patients with small cell lung…
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CLINICAL_TRIALS trial_result · 2026-04-24Clinical Trial Update: A Phase I/II Study of Sacituzumab Govitecan Plus Berzosertib in Small Cell Lung Cancer, Extra-Pulmonary Small Cell Neuroendocrine Cancer and Homologous Recombination-Deficient Cancers Resistant to PARP Inhibitors [Phase 1, Phase 2]
A Phase I/II clinical trial is evaluating the combination of sacituzumab govitecan and berzosertib in small cell lung cancer, extrapulmonary…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability [Phase 3]
Phase 3 trial evaluating whether high-dose radiation targeted to brain metastases with hippocampus-sparing approaches is better at preservin…
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Durvalumab Maintenance After Thoracic Chemoradiotherapy in Frail Small Cell Lung Cancer Patients Whose Disease is Limited to the Thorax [Phase 2]
Phase 2 trial evaluating durvalumab as maintenance therapy after thoracic chemoradiotherapy in frail patients with thorax-limited small cell…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Lay Navigation Intervention for Patients With Lung Cancer [NA]
This clinical trial update describes a lay navigation intervention intended to support patients with lung cancer, including non-small cell a…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Study of Sacituzumab Govitecan With Atezolizumab/Durvalumab as Maintenance Therapy for Extensive-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial evaluating sacituzumab govitecan with atezolizumab and durvalumab as maintenance therapy for extensive-stage small cell lung c…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: Nab-Paclitaxel Combined With Local Therapy in Relapsed SCLC [Phase 2]
This is a Phase 2 trial evaluating nab-paclitaxel with local therapy for relapsed small cell lung cancer (extensive stage). The study status…
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CLINICAL_TRIALS research · 2026-04-23Clinical Trial Update: A Study of ZL-1310 Versus Investigator's Choice of Therapy in Participants With Relapsed Small Cell Lung Cancer (DLLEVATE) [Phase 3]
Phase 3 clinical trial studying ZL-1310 versus investigator's choice of therapy in relapsed small cell lung cancer is currently recruiting.
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CLINICAL_TRIALS trial_result · 2026-04-23Clinical Trial Update: Tarlatamab for SCLC Brain Metastases [Phase 2]
Maastricht University Medical Center is conducting a Phase 2 trial of tarlatamab for adults with small cell lung cancer and brain metastases…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study to Examine the Safety of Different Doses of BG-68501 Given to Participants With Advanced-Stage Tumors [Phase 1]
BeiGene is conducting a Phase 1 safety study to evaluate different doses of BG-68501 in participants with various advanced-stage cancers, an…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: BMS-986489 (Atigotatug + Nivolumab) vs Durvalumab in Limited-stage Small-cell Lung Cancer (TIGOS-LS) [Phase 2]
Phase 2 trial evaluating BMS-986489 (Atigotatug) in combination with Nivolumab versus Durvalumab in limited-stage small cell lung cancer; tr…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Study of Tarlatamab in Combination With YL201 With or Without Anti-programmed Death Ligand 1 (PD-L1) in Participants With Extensive Stage (ES) Small Cell Lung Cancer (SCLC) [Phase 1]
A Phase 1 study evaluating Tarlatamab in combination with YL201, with or without anti-PD-L1, in extensive-stage small cell lung cancer is ac…
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CLINICAL_TRIALS trial_result · 2026-04-22Clinical Trial Update: Niraparib and Dostarlimab for the Treatment of Small Cell Lung Cancer and Other High-Grade Neuroendocrine Carcinomas [Phase 2]
Phase 2 clinical trial update evaluating niraparib and dostarlimab for small cell lung cancer and other high-grade neuroendocrine carcinomas…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: A Study of GSK5764227 in Participants With Relapsed Small Cell Lung Cancer (SCLC) [Phase 3]
A Phase 3 clinical trial is investigating GSK5764227 in participants with relapsed small cell lung cancer, with recruitment currently ongoin…
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CLINICAL_TRIALS research · 2026-04-22Clinical Trial Update: DSP-0390 in Combination With Atezolizumab for Small Cell Lung Cancer [Phase 1]
Phase 1 study of DSP-0390 in combination with atezolizumab for small cell lung cancer; the trial is not yet recruiting.
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CLINICAL_TRIALS research · 2026-04-21Clinical Trial Update: Durvalumab After Chemoradiotherapy in Limited Stage Small Cell Lung Cancer. [Phase 3]
Durvalumab is being studied after chemoradiotherapy in a Phase 3 trial for limited-stage small cell lung cancer, and the study is currently …