Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-10-16Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of INCB099318 in Participants With Advanced Solid Tumors [Phase 1]
Phase 1 clinical trial of INCB099318 in participants with advanced solid tumors has been terminated. The update reports safety, tolerability…
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CLINICAL_TRIALS research · 2025-10-16Clinical Trial Update: Quaratusugene Ozeplasmid (Reqorsa) and Atezolizumab Maintenance Therapy in ES-SCLC Patients [Phase 1, Phase 2]
Clinical trial update describing a Phase 1/2 study of Quaratusugene ozeplasmid (Reqorsa) in combination with atezolizumab maintenance therap…
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CLINICAL_TRIALS trial_result · 2025-10-15Clinical Trial Update: A Phase 1 Study Evaluating the Safety, Tolerability and Efficacy of AMG 119 in Subjects With RR SCLC [Phase 1]
Phase 1 study of AMG 119 in relapsed or refractory small cell lung cancer is currently suspended.
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CLINICAL_TRIALS research · 2025-10-15Clinical Trial Update: Predicting Responsiveness in Oncology Patients Based on Host Response Evaluation During Anti Cancer Treatments
An observational clinical trial from OncoHost Ltd. aims to predict responsiveness to anti-cancer treatments in patients with advanced cancer…
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CLINICAL_TRIALS research · 2025-10-14Clinical Trial Update: Study of JANX008 in Subjects With Advanced or Metastatic Solid Tumor Malignancies [Phase 1]
A Phase 1 study of JANX008 in advanced or metastatic solid tumors is currently recruiting, evaluating multiple indications including Non-Sma…
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CLINICAL_TRIALS trial_result · 2025-10-10Clinical Trial Update: A Phase 1 Study to Evaluate the Pharmacokinetics of JDQ443 in Participants With Hepatic Impairment Compared to Matched Healthy Control Participants. [Phase 1]
A Phase 1 pharmacokinetic study evaluating JDQ443 in participants with hepatic impairment compared with matched healthy controls has complet…
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CLINICAL_TRIALS trial_result · 2025-10-09Clinical Trial Update: A Phase II Clinical Trial to Evaluate Safety and Efficacy of XmAb20717 in Advanced Rare Cancers [Phase 2]
Phase II trial of XmAb20717 for advanced rare cancers has been suspended, with eligibility including microsatellite instability-high cancers…
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CLINICAL_TRIALS research · 2025-10-03Clinical Trial Update: Penfluridol for Relapsed/Refractory Small Cell Cancers [Phase 1, Phase 2]
Phase 1/2 clinical trial update evaluating penfluridol for relapsed or refractory small cell cancers; the study is not yet recruiting.
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FDA approval · 2025-10-02FDA Approved: ZEPZELCA — Supplemental Application (Jazz Pharmaceuticals, Inc.)
The FDA approved a supplemental application for ZEPZELCA (lurbinectedin) from Jazz Pharmaceuticals. This action pertains to the NDA for the …
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Thoracic Radiotherapy Plus Maintenance Durvalumab After First Line Carboplatin and Etoposide Plus Durvalumab in Extensive-stage Disease Small Cell Lung Cancer (ED-SCLC). [Phase 2]
A Phase 2 trial investigates thoracic radiotherapy with maintenance durvalumab after first-line carboplatin and etoposide plus durvalumab in…
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CLINICAL_TRIALS research · 2025-10-01Clinical Trial Update: Pragmatic Analysis of Complex Radiotherapy Cases In Cancer of the Lung
A clinical trial registry entry describing a pragmatic analysis of complex radiotherapy cases in lung cancer (non-small cell and small cell)…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer [NA]
Clinical trial update for NutriCare Plus, a medically tailored meal intervention, being studied in patients with various forms of lung cance…
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CLINICAL_TRIALS research · 2025-09-30Clinical Trial Update: Adebrelimab Plus Chemoradiotherapy Followed by Adebrelimab Maintenance in Limited-Stage SCLC [Phase 2]
Phase 2 clinical trial evaluating Adebrelimab in combination with chemoradiotherapy followed by Adebrelimab maintenance for limited-stage sm…
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CLINICAL_TRIALS research · 2025-09-26Clinical Trial Update: A Study of BL-B01D1, SI-B003 and BL-B01D1+SI-B003 in Patients With Extensive Stage Small Cell Lung Cancer [Phase 2]
A Phase 2 clinical trial evaluating BL-B01D1, SI-B003, and their combination in extensive-stage small cell lung cancer is currently recruiti…
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CLINICAL_TRIALS trial_result · 2025-09-25Clinical Trial Update: A Study With NKT3447 for Adults With Advanced/Metastatic Solid Tumors [Phase 1]
Phase 1 trial of NKT3447 in adults with advanced or metastatic solid tumors has been terminated. The study encompassed indications including…
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CLINICAL_TRIALS trial_result · 2025-09-24Clinical Trial Update: Durvalumab Plus Etoposide-free Chemotherapy in First-line Treatment of Extensive-disease Small-sell Lung Cancer (SCLC) [Phase 2]
Phase 2 trial evaluating durvalumab with etoposide-free chemotherapy as first-line treatment for extensive-stage small cell lung cancer; cur…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of the c-Kit Specific Antibody-Drug Conjugate NN3201 for Advanced and/or Metastatic Solid Tumors Known to Express c-Kit [Phase 1]
Phase 1 study evaluating NN3201, a c-Kit targeted antibody-drug conjugate, in advanced and/or metastatic solid tumors expressing c-Kit; curr…
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLC [Phase 2]
Phase 2 clinical trial evaluating AL8326 for safety and efficacy in second-line or later small cell lung cancer is currently active but not …
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CLINICAL_TRIALS research · 2025-09-23Clinical Trial Update: A Study of Peluntamig (PT217) in Patients With Neuroendocrine Carcinomas Expressing DLL3 (the SKYBRIDGE Study) [Phase 1, Phase 2]
Phase 1/2 SKYBRIDGE study evaluating Peluntamig (PT217) in DLL3-expressing neuroendocrine carcinomas; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-22Clinical Trial Update: Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) [Phase 2]
Pembrolizumab is being studied in a Phase 2 trial (MK-3475-158/KEYNOTE-158) for advanced solid tumors; the study is currently active but not…
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CLINICAL_TRIALS research · 2025-09-18Clinical Trial Update: A Study of BL-M14D1 in Patients With Locally Advanced or Metastatic Small Cell Lung Cancer, Neuroendocrine Tumors and Other Solid Tumors [Phase 1]
Phase 1 clinical trial evaluating BL-M14D1 in locally advanced or metastatic small cell lung cancer, neuroendocrine tumors, and other solid …
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: A Single-arm, Open-label, Phase II Study to Evaluate Efficacy, Safety and Pharmacokinetics of HLX10 + Chemotherapy in Patients With ES-SCLC [Phase 2]
A Phase II, single-arm, open-label trial evaluating HLX10 in combination with chemotherapy for extensive-stage small cell lung cancer; the s…
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CLINICAL_TRIALS research · 2025-09-17Clinical Trial Update: Clinical Benefit and Biomarker Analysis of Combination of PD-1/PD-L1 Immune Checkpoint Inhibitors and Radiotherapy
A clinical trial is evaluating the combination of PD-1/PD-L1 immune checkpoint inhibitors with radiotherapy across several cancers to assess…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: Observational Study to Evaluate the Safety and Efficacy of Zepzelca™ Injection
Observational study to evaluate the safety and efficacy of Zepzelca (lurbinectedin) injection; sponsor is Boryung Pharmaceutical Co., Ltd, c…
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CLINICAL_TRIALS research · 2025-09-16Clinical Trial Update: ALG-LungCancerRegistry (SAFRO2202)
An ongoing clinical trial registry in Algeria (SAFRO2202) for lung cancer is recruiting patients with non-small cell lung cancer, small cell…