Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-05Clinical Trial Update: Prospective Feasibility Pilot Study Evaluating the Value of [68Ga]Ga-PENTIXAFOR PET-CT in Patients With Metastatic Small Cell Lung Cancer (SCLC) at Diagnosis and Disease Progression [EARLY_Phase 1]
An early Phase 1 feasibility trial evaluating 68Ga-PENTIXAFOR PET-CT imaging for CXCR4 targeting in metastatic small cell lung cancer at dia…
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CLINICAL_TRIALS trial_result · 2025-06-05Clinical Trial Update: Pembrolizumab After Radiation Therapy and Chemotherapy in Limited Stage Small Cell Lung Cancer [Phase 2]
Phase 2 trial of pembrolizumab after radiation therapy and chemotherapy in limited-stage small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-06-04Clinical Trial Update: Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer. [Phase 1, Phase 2]
Clinical trial evaluating the combination of lurbinectedin and pembrolizumab in small cell lung cancer. The study's Phase 1 and Phase 2 port…
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CLINICAL_TRIALS trial_result · 2025-05-30Clinical Trial Update: Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008) [Phase 3]
A Phase 3 trial evaluating pembrolizumab plus vibostolimab (MK-7684A) or atezolizumab in combination with chemotherapy as first-line treatme…
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CLINICAL_TRIALS other · 2025-05-28Clinical Trial Update: PD-L1 Inhibitor Combined With Apatinib as First-line Maintenance Treatment for Extensive-stage Small Cell Lung Cancer [Phase 2]
A Phase 2 trial is evaluating a PD-L1 inhibitor in combination with apatinib as first-line maintenance therapy for extensive-stage small cel…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: Safety, Pharmacokinetics and Preliminary Efficacy of CS231295 in Advanced Solid Tumors [Phase 1]
A Phase 1 trial from Chipscreen Biosciences assesses safety, pharmacokinetics, and preliminary efficacy of CS231295 in adults with advanced …
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: S1827 (MAVERICK) Testing Whether the Use of Brain Scans Alone Instead of Brain Scans Plus Preventive Brain Radiation Affects Lifespan in Patients With Small Cell Lung Cancer [Phase 3]
Phase 3 MAVERICK trial S1827 is evaluating whether brain scans alone (without preventive brain radiation) affect lifespan in patients with s…
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CLINICAL_TRIALS trial_result · 2025-05-23Clinical Trial Update: Trial of NanoPac Intratumoral Injection in Lung Cancer [Phase 2]
A Phase 2 trial of NanoPac intratumoral injection in lung cancer has completed and results have been posted.
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CLINICAL_TRIALS research · 2025-05-23Clinical Trial Update: Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC [Phase 1, Phase 2]
Status update on ONC-392 showing safety, pharmacokinetics, and preliminary efficacy in monotherapy and in combination with anti-PD-1 across …
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Phase I-II, FIH, TROP2 ADC, Advanced Unresectable/Metastatic Solid Tumors, Refractory to Standard Therapies (KL264-01) [Phase 1, Phase 2]
KL264-01, a Trop2-targeted antibody-drug conjugate, is being studied in a Phase 1/2 trial for advanced unresectable or metastatic solid tumo…
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CLINICAL_TRIALS research · 2025-05-20Clinical Trial Update: Maintenance Durvalumab (MEDI4736) and Olaparib (AZD2281) After Standard 1st Line Treatment (Carboplatin/Cisplatin, Etoposide, Durvalumab) in HRD Positive Extensive Disease (ED) Small-cell Lung Cancer (SCLC) [Phase 2]
Phase 2 clinical trial evaluating maintenance durvalumab and olaparib after first-line therapy in HRD-positive extensive-disease small cell …
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CLINICAL_TRIALS research · 2025-05-18Clinical Trial Update: This is a Two-cohort, Exploratory Clinical Study Assessing the Activity of Benmelstobart Combined With Chemotherapy With or Without Anlotinib in Resectable Limited-Stage Small Cell Lung Cancer [Phase 2]
Phase 2 exploratory clinical trial evaluating Benmelstobart with chemotherapy, with or without Anlotinib, in resectable limited-stage small …
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CLINICAL_TRIALS research · 2025-05-16Clinical Trial Update: Phase I Clinical Study of α-PD-L1/DLL3 CAR-T in Patients With R/R SCLC [Phase 1]
Phase I study of α-PD-L1/DLL3 CAR-T therapy in patients with relapsed/refractory small cell lung cancer (extensive stage) is currently recru…
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CLINICAL_TRIALS other · 2025-05-14Clinical Trial Update: RAPA-201 Therapy of Solid Tumors [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating RAPA-201 for solid tumors, including small cell and non-small cell lung cancer and several head and neck…
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CLINICAL_TRIALS research · 2025-05-14Clinical Trial Update: A Study of SYS6040 for Injection in Patients With Advanced Solid Tumors [Phase 1]
This entry describes a Phase 1 clinical trial of SYS6040 for injection in patients with small cell lung cancer and other advanced solid tumo…
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CLINICAL_TRIALS trial_result · 2025-05-09Clinical Trial Update: M7824 and Topotecan or Temozolomide in Relapsed Small Cell Lung Cancers [Phase 1, Phase 2]
A Phase 1/2 trial evaluating M7824 (bintrafusp alfa) in combination with Topotecan or Temozolomide for relapsed small cell lung cancer. The …
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CLINICAL_TRIALS trial_result · 2025-05-08Clinical Trial Update: Surufatinib in Combination With Tislelizumab in Subjects With Advanced Solid Tumors [Phase 1, Phase 2]
The Phase 1/2 trial of surufatinib in combination with tislelizumab for advanced solid tumors has been terminated. Results were posted on 20…
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CLINICAL_TRIALS research · 2025-05-02Clinical Trial Update: Quantifying Systemic Immunosuppression to Personalize Cancer Therapy
A clinical trial update describing a study to quantify systemic immunosuppression to personalize cancer therapy and that the trial is curren…
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FDA approval · 2025-04-30FDA Approved: ZEPZELCA — Supplemental Application (Jazz Pharmaceuticals, Inc.)
FDA approved a supplemental application for Zepzelca (lurbinectedin) by Jazz Pharmaceuticals, Inc. The action approves changes to the drug's…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: IN10018 Combination Therapy in Treatment-naïve ES-SCLC [Phase 1, Phase 2]
Clinical trial update for IN10018 combination therapy in treatment-naïve extensive-stage small cell lung cancer. The study is in Phase 1 and…
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CLINICAL_TRIALS research · 2025-04-30Clinical Trial Update: Prospective, Single-arm, Phase II Clinical Study of Irinotecan Hydrochloride Liposome Injection Combined With Platinum and Immune Checkpoint Inhibitors Combined With Anlotinib for the Maintenance of Extensive Small Cell Lung Cancer After First-line Induction [Phase 4]
This clinical trial update describes a prospective, single-arm study evaluating irinotecan liposome injection with platinum-based chemothera…
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CLINICAL_TRIALS research · 2025-04-25Clinical Trial Update: Hypofractionated Radiotherapy Followed by Chemo-immunotherapy Induction Therapy [Phase 2]
A Phase 2 trial is investigating hypofractionated radiotherapy followed by chemo-immunotherapy induction in limited-stage small cell lung ca…
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CLINICAL_TRIALS trial_result · 2025-04-17Clinical Trial Update: A Study to Evaluate Subcutaneous Durvalumab in Patients With Non-Small Cell Lung Cancer and Small Cell Lung Cancer [Phase 1]
A Phase 1 trial evaluating subcutaneous durvalumab for non-small cell lung cancer and small cell lung cancer was terminated.
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CLINICAL_TRIALS trial_result · 2025-04-16Clinical Trial Update: Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer [Phase 1, Phase 2]
Phase 1/2 study of endobronchial ultrasound-guided interstitial photodynamic therapy for locally advanced lung cancer was terminated, with r…
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CLINICAL_TRIALS research · 2025-04-15Clinical Trial Update: A Study of Adebrelimab Combined With Apatinib Mesylate and Chemotherapy for Neoadjuvant Therapy and Biomarker Analysis in Limited-stage Small Cell Lung Cancer [Phase 2]
Phase 2 study evaluating adebrelimab plus apatinib mesylate and chemotherapy as neoadjuvant therapy for limited-stage small cell lung cancer…