Small Cell Lung Cancer
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-07-21Clinical Trial Update: A Phase II/III Study of IBB0979 in Combination With Topotecan Versus Topotecan in Relapsed Small Cell Lung Cancer [Phase 2]
A Phase II/III trial is planned to compare IBB0979 plus topotecan versus topotecan alone in relapsed small cell lung cancer; the study is no…
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CLINICAL_TRIALS research · 2025-07-20Clinical Trial Update: Rapid Autopsy Protocol for Patients With Small Cell Lung Cancer
A clinical trial update describing a rapid autopsy protocol for patients with small cell lung cancer, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-20Clinical Trial Update: Ipilimumab and Nivolumab in Recurrent Extensive Stage Small Cell Lung Cancer After Receiving Platinum-based Chemotherapy [Phase 2]
This Phase 2 trial evaluates the combination of ipilimumab and nivolumab in patients with recurrent extensive-stage small cell lung cancer f…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: SRS/SRT/Hypo-RT Versus HA-WBRT for No More Than 10 Brain Metastases in SCLC [Phase 3]
Phase 3 clinical trial comparing SRS/SRT/Hypo-RT to hippocampal-avoidance whole-brain radiotherapy for patients with up to 10 brain metastas…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: A Study on the First-line Treatment of Small Cell Lung Cancer With Adebrelimab and Vunakizumab and Chemotherapy [Phase 2]
A Phase 2 trial is evaluating first-line treatment of small cell lung cancer using adebrelimab and vunakizumab in combination with chemother…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: A Long-Term Follow-Up Study of Participants Treated With A2 Biotherapeutics (A2 Bio) Gene Therapy (GT) Products
This clinical trial update reports long-term follow-up of participants treated with A2 Biotherapeutics' gene therapy products in solid tumor…
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CLINICAL_TRIALS research · 2025-07-15Clinical Trial Update: Prospective Study of Intensity-Modulated Proton Therapy (IMPT) for Small Cell Lung Cancer [NA]
Prospective study evaluating intensity-modulated proton therapy for small cell lung cancer is currently recruiting. The study is sponsored b…
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CLINICAL_TRIALS research · 2025-07-14Clinical Trial Update: Phase 1 Study of HS-20093 Combinations in Patients With Extensive Stage Small Cell Lung Cancer [Phase 1]
Clinical trial update describing a Phase 1 study of HS-20093 in combination regimens for extensive-stage small cell lung cancer; the study i…
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CLINICAL_TRIALS trial_result · 2025-07-10Clinical Trial Update: 89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors [Phase 2]
Telix's phase 2 trial of the CAIX-targeting PET tracer 89Zr-girentuximab in CAIX-positive solid tumors was terminated.
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Trial of EP0057, a Nanoparticle Camptothecin With Olaparib in People With Relapsed/Refractory Small Cell Lung Cancer [Phase 1, Phase 2]
NCI-sponsored trial EP0057 (camptothecin nanoparticle) combined with olaparib in relapsed/refractory small cell lung cancer completed Phase …
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CLINICAL_TRIALS trial_result · 2025-07-09Clinical Trial Update: Pharmacokinetic Study of Lurbinectedin in Combination With Irinotecan in Patients With Selected Solid Tumors [Phase 1, Phase 2]
A pharmacokinetic study evaluating the combination of lurbinectedin and irinotecan in selected solid tumors has completed (Phase 1/Phase 2).
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CLINICAL_TRIALS trial_result · 2025-07-02Clinical Trial Update: Placebo-controlled, Study of Concurrent Chemoradiation Therapy With Pembrolizumab Followed by Pembrolizumab and Olaparib in Newly Diagnosed Treatment-Naïve Limited-Stage Small Cell Lung Cancer (LS-SCLC) (MK 7339-013/KEYLYNK-013) [Phase 3]
Phase 3 trial evaluating concurrent chemoradiation with pembrolizumab, followed by pembrolizumab and olaparib, in newly diagnosed treatment-…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of infusions of iNKT cells and CD8+ T cells in patients with advanced solid tu…
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CLINICAL_TRIALS trial_result · 2025-06-29Clinical Trial Update: A Study of Fluzoparib (SHR-3162) and Temozolomide With or Without SHR-1316 in Treating Patients With Replapsed Small Cell Lung Cancer [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating Fluzoparib (SHR-3162) with temozolomide, with or without SHR-1316, in relapsed small cell lung cancer …
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CLINICAL_TRIALS research · 2025-06-26Clinical Trial Update: Radiotherapy or Observation of Liver Metastases in Small Cell Lung Cancer [NA]
A clinical trial comparing radiotherapy versus observation for liver metastases in small cell lung cancer; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-06-24Clinical Trial Update: REAL-WORLD DURVALUMAB IN EXTENSIVE-STAGE SMALL CELL LUNG CANCER
Clinical trial update showing real-world use of durvalumab in extensive-stage small cell lung cancer; the study has completed.
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: A Study of MHB088C Injection Versus Treatment of Physician's Choice in Subjects With Relapsed Small Cell Lung Cancer [Phase 3]
A Phase 3 trial evaluating MHB088C injection vs physician's choice in relapsed extensive-stage small cell lung cancer is currently recruitin…
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CLINICAL_TRIALS research · 2025-06-18Clinical Trial Update: A Multi-omics Sequencing-based Model for Predicting Efficacy and Dynamic Monitoring of Treatment in Small Cell Lung Cancer
A clinical trial is evaluating a multi-omics sequencing-based model to predict treatment efficacy and dynamically monitor response in small …
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: Dose-escalated Adaptive Radiotherapy of Thoracic Disease for Small Cell Lung Cancer [Phase 2]
This document provides an update on a Phase 2 clinical trial evaluating dose-escalated adaptive radiotherapy for thoracic disease in small c…
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CLINICAL_TRIALS research · 2025-06-12Clinical Trial Update: To Evaluate Efficacy and Safety of TT-00420 (Tinengotinib) as Monotherapy and Combination Therapy in Patients With Advanced Solid Tumors [Phase 1, Phase 2]
This update covers a completed Phase 1/2 clinical trial evaluating Tinengotinib (TT-00420) as both monotherapy and in combination therapy fo…
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: PEI REGIMEN: A Therapeutic Option in Small Cell Lung Cancer? A Monoinstitutional Experience of 46 Consecutive Cases
A monoinstitutional retrospective report of 46 consecutive small cell lung cancer patients treated with the PEI REGIMEN, providing real-worl…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Efficacy and Biomarkers of the Second-line Treatment of Adebelizumab Combined With Irinotecan Liposome in Advanced Small Cell Lung Cancer [Phase 2]
Phase 2 clinical trial evaluating the efficacy and biomarkers of Adebelizumab in combination with liposomal irinotecan as a second-line trea…
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CLINICAL_TRIALS trial_result · 2025-06-06Clinical Trial Update: Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery [Phase 3]
Phase 3 trial comparing hippocampus-sparing whole-brain radiotherapy to stereotactic radiosurgery for patients with brain metastases from va…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Omitting CTV for Primary Tumor in LS-SCLC [Phase 3]
Phase 3 clinical trial update evaluating omitting the clinical target volume (CTV) for the primary tumor in limited-stage small cell lung ca…
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CLINICAL_TRIALS research · 2025-06-06Clinical Trial Update: Two Schedules of Hyperfractionated Thoracic Radiotherapy in Limited Disease Small Cell Lung Cancer [NA]
This clinical trial update describes two hyperfractionated thoracic radiotherapy schedules for limited-stage small cell lung cancer; the stu…