Sjogren Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2026-07-07Clinical Trial Update: Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome [Phase 3]
Phase 3 trial of ianalumab (VAY736) in active Sjogren's syndrome completed.
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CLINICAL_TRIALS trial_result · 2026-06-03Clinical Trial Update: Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome [Phase 3]
Phase 3 trial assessing efficacy and safety of ianalumab (VAY736) for active Sjogren's syndrome.
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CLINICAL_TRIALS trial_result · 2026-04-29Clinical Trial Update: A Randomized, Double-blind 2-arm, Followed by an Open-label 1-arm, NEPTUNUS Extension Study to Assess the Long-term Safety and Efficacy of Ianalumab in Patients With Sjogrens Syndrome. [Phase 3]
A Phase 3 randomized trial followed by open-label extension evaluating long-term safety and efficacy of ianalumab in Sjogren's syndrome.
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease [Phase 2]
Phase 2 clinical trial assessing the safety of tofacitinib, a JAK inhibitor, in primary Sjogren's syndrome; the study is currently recruitin…
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CLINICAL_TRIALS trial_result · 2026-03-11Clinical Trial Update: Efficacy and Safety of Baricitinib in Sjogren's Syndrome [Phase 2]
Phase 2 trial evaluating efficacy and safety of baricitinib in Sjogren's syndrome has completed.
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CLINICAL_TRIALS research · 2026-03-06Clinical Trial Update: Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases [EARLY_Phase 1]
An early-phase 1 clinical trial evaluating a targeted CD19 or CD19-BCMA CAR-T therapy for autoimmune diseases is currently recruiting.
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CLINICAL_TRIALS research · 2026-02-13Clinical Trial Update: Rheumatology Patient Registry and Biorepository
This Clinical Trial Update describes a Yale University-led rheumatology patient registry and biorepository that is currently recruiting to c…
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Generative AI Impact on Rheumatoid Arthritis Complications Diagnosis
A clinical trial in China is evaluating whether generative AI can improve the diagnosis of complications associated with rheumatoid arthriti…
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CLINICAL_TRIALS trial_result · 2025-12-18Clinical Trial Update: Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren's Syndrome [Phase 1, Phase 2]
A phase 1/2 clinical trial update reports safety data for tofacitinib, an oral JAK inhibitor, in patients with Sjogren's syndrome, with resu…
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CLINICAL_TRIALS research · 2025-10-24Clinical Trial Update: A Phase 2 Study to Investigate Efficacy and Safety of HZN-1116 in Participants With Sjogren's Syndrome [Phase 2]
Phase 2 study evaluating HZN-1116 for Sjogren's Syndrome is currently ACTIVE_NOT_RECRUITING.
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CLINICAL_TRIALS trial_result · 2025-10-01Clinical Trial Update: A Study to Evaluate the Efficacy and Safety of Telitacicept in Subjects With Active Primary Sjogren's Syndrome [Phase 3]
Phase 3 study evaluating the efficacy and safety of Telitacicept in active Primary Sjogren's Syndrome has completed.
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CLINICAL_TRIALS research · 2025-09-19Clinical Trial Update: Clinical Study of BCMA/CD70-targeted CAR-T Therapy for Refractory Pediatric Rheumatic Diseases [Phase 1]
Phase 1 clinical trial evaluating a BCMA/CD70-targeted CAR-T therapy for refractory pediatric rheumatic diseases is currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-09-15Clinical Trial Update: Safety and Tolerability of IBI355 in Patients With Primary Sjogren's Syndrome [Phase 1]
Phase 1 clinical trial update reports safety and tolerability findings for the investigational therapy IBI355 in patients with primary Sjogr…
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CLINICAL_TRIALS research · 2025-08-20Clinical Trial Update: Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases [Phase 1, Phase 2]
This clinical trial update describes a phase 1/2 study evaluating universal CD19-targeting CAR-γδT cells for refractory autoimmune diseases,…
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CLINICAL_TRIALS trial_result · 2025-04-02Clinical Trial Update: BCMA-CD19 CAR-T Therapy for Refractory Autoimmune Diseases [Phase 2]
Phase 2 clinical trial update on BCMA-CD19 CAR-T therapy for refractory autoimmune diseases, currently recruiting. The study targets several…
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CLINICAL_TRIALS research · 2025-03-30Clinical Trial Update: Wheat-free Diet in the Treatment of Sjogren's Syndrome [NA]
This document reports a clinical trial evaluating a wheat-free diet for the treatment of Sjogren's Syndrome; the study is currently recruiti…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Assessment of Physician Consideration of EPRO's, from Patients with Gout, Rheumatoid Arthritis, Sjogren's Syndrome or Systemic Lupus, on the Frequency of Therapeutic Adjustments
A Strasbourg-based study is evaluating whether physician consideration of electronic patient-reported outcomes from patients with gout, rheu…
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CLINICAL_TRIALS research · 2025-03-11Clinical Trial Update: Ro60 Expression in Macrophages in Sjogren's Disease [NA]
Clinical trial NCT06324968 investigates Ro60 expression in macrophages in Sjogren's syndrome, sponsored by Centre Hospitalier Universitaire …
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Study to Evaluate Safety and Efficacy of Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease [Phase 3]
Phase 3 trial evaluating safety and efficacy of Cenegermin (Oxervate) versus vehicle for severe Sjogren's dry eye disease has completed, wit…
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CLINICAL_TRIALS trial_result · 2024-10-29Clinical Trial Update: Safety and Efficacy of VAY736 in Patients With Primary Sjogren's Syndrome (pSS) [Phase 2]
Phase 2 trial evaluating the safety and efficacy of VAY736 in patients with primary Sjogren's syndrome has completed, with results posted.
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CLINICAL_TRIALS research · 2024-08-06Clinical Trial Update: Functional Analysis of Salivary Glands and Correlation With Sialoscintigraphy in Sjogren's Syndrome [NA]
A recruiting clinical trial evaluating functional analysis of salivary glands and its correlation with sialoscintigraphy in Sjogren's syndro…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: Belimumab After Rituximab in Resistant Primary Juvenile SS [Phase 4]
Phase 4 trial evaluating belimumab after rituximab in resistant primary Sjogren's syndrome is currently recruiting.
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: Fish Oil (Omega 3 ) in Sjogren's Syndrome [Phase 2, Phase 3]
A completed Phase 2/Phase 3 trial evaluating fish oil (omega-3) in Sjogren's syndrome.
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CLINICAL_TRIALS trial_result · 2023-08-09Clinical Trial Update: the Effect of Mixture of Natural Products As Salivary Substitutes in Treatment Of Xerostomia [Phase 3]
Phase 3 clinical trial evaluating a mixture of natural products as salivary substitutes for xerostomia in Sjogren's syndrome; study complete…
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CLINICAL_TRIALS trial_result · 2023-01-23Clinical Trial Update: Tacrolimus Plus Glucocorticoid for Severe Thrombocytopenia in SS [Phase 2, Phase 3]
A phase 2/3 trial evaluating tacrolimus plus glucocorticoid for severe thrombocytopenia in Sjogren syndrome with other organ involvement is …