Sjogren Syndrome
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-12-19Clinical Trial Update: Anifrolumab Treatment for 24 Weeks in Patients With Primary Sjögren's Syndrome [Phase 2]
A Phase 2 clinical trial evaluating anifrolumab for 24 weeks in patients with Sjögren's syndrome.
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CLINICAL_TRIALS withdrawal · 2022-01-27Clinical Trial Update: BAFF/IL-17 Bispecific Antibody Treatment in Subjects With Primary Sjogren's Syndrome [Phase 2, Phase 3]
A BAFF/IL-17 bispecific antibody trial for Primary Sjogren's Syndrome has been withdrawn (Phase 2/Phase 3).
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CLINICAL_TRIALS trial_result · 2021-08-24Clinical Trial Update: Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye [Phase 3]
Phase 3 trial update on platelet-rich plasma injections for severe dry eye, including Sjogren syndrome; study completed with posted results.
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: Beta-3 Agonist and Anti-muscarinic Agent for Sjogren's Syndrome With Overactive Bladder [Phase 4]
Phase 4 clinical trial update investigating a beta-3 agonist and an anti-muscarinic agent for Sjogren's syndrome with overactive bladder.
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CLINICAL_TRIALS trial_result · 2021-06-09Clinical Trial Update: Safety and Efficacy Study of Subcutaneous Belimumab and Intravenous Rituximab Co-administration in Subjects With Primary Sjogren's Syndrome [Phase 2]
Phase 2 trial evaluating safety and efficacy of subcutaneous belimumab with intravenous rituximab co-administration in primary Sjögren's syn…
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CLINICAL_TRIALS trial_result · 2021-05-11Clinical Trial Update: Sjogrens Syndrome Measured by Ultrasound [Phase 2]
Phase 2 clinical trial update assessing ultrasound-based measurements in Sjogren's syndrome.
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CLINICAL_TRIALS trial_result · 2021-04-02Clinical Trial Update: A Study of RSLV-132 in Subjects With Primary Sjogren's Syndrome [Phase 2]
Phase 2 clinical trial of RSLV-132 in subjects with primary Sjögren's syndrome has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-22Clinical Trial Update: Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease [Phase 4]
Phase 4 safety study evaluating topical cyclosporine for dry eye disease, involving patients with Sjögren-related dry eye.
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CLINICAL_TRIALS trial_result · 2020-08-25Clinical Trial Update: TrueTear in Sjogren's Disease Patients [NA]
Clinical trial update for TrueTear in Sjogren's syndrome-associated dry eye has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-07-14Clinical Trial Update: Oral Pilocarpine in the Treatment of the Dry Eye of Patients With Sjogrens Syndrome [Phase 3]
Phase 3 clinical trial update evaluating oral pilocarpine for the treatment of dry eye in patients with Sjögren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2020-05-22Clinical Trial Update: Cyclosporine A in the TReatment of Interstitial Pneumonitis Associated With Sjogren's Syndrome [Phase 4]
Phase 4 trial investigating cyclosporine A for interstitial pneumonitis associated with Sjogren's syndrome.
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Study to Assess Safety and Efficacy of Filgotinib, Lanraplenib and Tirabrutinib in Adults With Active Sjogren's Syndrome [Phase 2]
A Phase 2 study evaluating safety and efficacy of filgotinib, lanraplenib, and tirabrutinib in adults with active Sjogren's syndrome has com…
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CLINICAL_TRIALS trial_result · 2019-05-22Clinical Trial Update: Comparing Effect of Topical Tacrolimus 0.03% Versus Cyclosporine 0.05% in Dry Eyes of Secondary Sjogren Syndrome [Phase 3]
A Phase 3 trial comparing topical tacrolimus 0.03% versus cyclosporine 0.05% in dry eye associated with Sjogren syndrome has completed.
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CLINICAL_TRIALS trial_result · 2019-04-26Clinical Trial Update: Evaluation of Influenza A/H3N2 Vaccine in Patients With Rheumatologic Diseases [Phase 4]
Phase 4 trial evaluating an influenza A/H3N2 vaccine in patients with systemic lupus erythematosus and Sjogren's syndrome has completed.
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CLINICAL_TRIALS trial_result · 2019-04-23Clinical Trial Update: An Evaluation of the Impact of a Single Dose of P-552 on Oral Mucosal Wetness [Phase 1, Phase 2]
Phase 1/2 trial evaluating a single dose of P-552 for oral mucosal wetness in xerostomia and Sjogren's syndrome. Study status completed.
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CLINICAL_TRIALS trial_result · 2018-08-01Clinical Trial Update: A Study to Assess the Efficacy of RO5459072 in Participants With Primary Sjogren's Syndrome [Phase 2]
Phase 2 trial evaluating RO5459072 for primary Sjogren's syndrome has completed; results were posted in 2018.
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CLINICAL_TRIALS trial_result · 2017-10-20Clinical Trial Update: Anti-CD20 Antibody Therapy for Sjogren's Syndrome [Phase 1]
Phase 1 trial update reporting the completion of a study evaluating an anti-CD20 antibody therapy for Sjogren's syndrome.
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CLINICAL_TRIALS withdrawal · 2017-08-08Clinical Trial Update: Examining the Immunological Process of Autoimmune Patients
A University of Florida-sponsored clinical trial examining immune processes in autoimmune patients, including Sjogren's syndrome, has been w…
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Evaluation of Salivary Gland Dysfunction
A clinical trial evaluating salivary gland dysfunction sponsored by the National Institute of Dental and Craniofacial Research has been term…
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CLINICAL_TRIALS research · 2017-02-27Clinical Trial Update: Blood Based Eyedrops From Different Sources in the Treatment of Severe Keratopathy [NA]
A clinical trial is evaluating blood-based eyedrops from different sources for severe keratopathy, including keratopathy associated with Sjo…
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CLINICAL_TRIALS trial_result · 2013-05-10Clinical Trial Update: Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops [Phase 4]
A phase 4 trial evaluating 0.03% tacrolimus eye drops for dry eye symptoms in Sjogren's syndrome has completed.
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FDA label_change · 2013-04-26FDA Approved: SALAGEN — Supplemental Application (Advanz Pharma (US) Corp.)
The FDA approved a supplemental application for Salagen (pilocarpine hydrochloride) from Advanz Pharma (US) Corp., resulting in changes to t…
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FDA approval · 2010-06-22FDA Approved: PILOCARPINE HYDROCHLORIDE — Original Application (Sandoz Inc)
FDA approves Sandoz Inc's original application for pilocarpine hydrochloride tablets, establishing a generic option indicated for xerostomia…
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CLINICAL_TRIALS trial_result · 2010-04-12Clinical Trial Update: Assessment of Inflammatory Biomarkers Expressed in a Sjogren's Population: Effect of a Topical Steroid Intervention [Phase 4]
Phase 4 clinical trial assessing inflammatory biomarkers in Sjogren's Syndrome and the effect of a topical steroid intervention; results hav…
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CLINICAL_TRIALS research · 2009-06-15Clinical Trial Update: Confocal Microscopy and Lacrimal Gland in Sjogren's Syndrome
This clinical trial update describes an investigation using confocal microscopy of the lacrimal gland in primary Sjogren's Syndrome; the cur…