Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2012-07-26Clinical Trial Update: Angiotensin-converting Enzyme Inhibitors and Early Sickle Cell Renal Disease in Children [NA]
This update reports on a terminated clinical trial evaluating angiotensin-converting enzyme inhibitors for early sickle cell renal disease i…
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CLINICAL_TRIALS trial_result · 2012-05-03Clinical Trial Update: Prasugrel Versus Placebo in Adult Sickle Cell Disease [Phase 2]
Phase 2 trial comparing prasugrel with placebo in adults with sickle cell disease has completed; results were posted in 2012.
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CLINICAL_TRIALS trial_result · 2012-05-01Clinical Trial Update: Evaluation of Efficacy of Zoledronic Acid in Patients With Haemoglobin Syndromes (Thalassemia and Sicle Cell Anaemia) and Risk of Skeletal Events [Phase 4]
A Phase 4 clinical trial evaluating the efficacy of zoledronic acid in patients with hemoglobin disorders (thalassemia and sickle cell disea…
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CLINICAL_TRIALS trial_result · 2012-03-06Clinical Trial Update: Phase III Randomized Study of Poloxamer 188 for Vaso-Occlusive Crisis of Sickle Cell Disease [Phase 3]
A Phase III randomized study evaluating Poloxamer 188 for vaso-occlusive crisis in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2012-02-15Clinical Trial Update: An Assessment of Prasugrel on Healthy Adults and Sickle Cell Adults [Phase 1]
Phase 1 trial assessing prasugrel in healthy adults and adults with sickle cell disease; results were posted in 2012.
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CLINICAL_TRIALS research · 2012-02-06Clinical Trial Update: Study Of Efficacy,Safety of Combined Deferasirox and Deferiprone Versus Combined Deferiprone and Desferal In Conditions of Iron Overload [Phase 2, Phase 3]
A Phase 2/3 clinical trial comparing the combination of deferasirox and deferiprone to the combination of deferiprone and deferoxamine (Desf…
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FDA label_change · 2012-01-26FDA Approved: DROXIA — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for DROXIA (hydroxyurea) from Waylis Therapeutics LLC, indicating a label change/expansion. The docu…
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CLINICAL_TRIALS trial_result · 2012-01-04Clinical Trial Update: Aspirin Prophylaxis in Sickle Cell Disease [Phase 1]
A Phase 1 trial evaluated aspirin prophylaxis in patients with sickle cell disease; results were posted after completion in 2012.
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CLINICAL_TRIALS withdrawal · 2011-11-11Clinical Trial Update: Phase 1 Study of Zoledronic Acid in Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/Phase 2 trial evaluating zoledronic acid for sickle cell disease has been withdrawn.
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CLINICAL_TRIALS research · 2011-08-26Clinical Trial Update: Clinical and Laboratory Characteristics of Sickle Cell Anemia Patients Admitted With Fever
Completed clinical study describing the clinical and laboratory characteristics of patients with sickle cell disease admitted with fever, in…
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: Blood Transfusions in Thalassemia Patients, Complications and Adverse Effects
This completed trial reports on blood transfusion practices in thalassemia patients, focusing on complications and adverse effects associate…
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: Clinical and Laboratory Assessment of Iron Overload in Sickle Cell Anemia and Sickle Cell Thalassemia
This clinical trial update reports on clinical and laboratory assessments of iron overload in patients with sickle cell anemia and in those …
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: The Spleen in Sickle Cell Anemia and Sickle Cell Thalassemia
A completed clinical trial sponsored by HaEmek Medical Center evaluating the spleen in patients with sickle cell anemia and thalassemia.
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CLINICAL_TRIALS trial_result · 2011-08-26Clinical Trial Update: Iron Overload Assesment in Sickle Cell Anemia and Sickle Cell Thalassemia [NA]
This document reports a completed clinical trial update evaluating iron overload assessment in patients with sickle cell anemia and sickle c…
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CLINICAL_TRIALS trial_result · 2011-08-01Clinical Trial Update: Phase 1/2 Study to Evaluate the Safety, Tolerability and Pharmacokinetics of HQK-1001 Administered Daily in Patients With Sickle Cell Disease [Phase 1, Phase 2]
This update summarizes a Phase 1/2 clinical trial evaluating HQK-1001 for safety, tolerability, and pharmacokinetics in patients with sickle…
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CLINICAL_TRIALS trial_result · 2011-07-18Clinical Trial Update: A Study of the Efficacy and Safety of ICA-17043 (With or Without Hydroxyurea) in Patients With Sickle Cell Anemia. [Phase 2]
Phase 2 study evaluating the efficacy and safety of ICA-17043 (senicapoc), with or without hydroxyurea, in patients with sickle cell disease…
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CLINICAL_TRIALS trial_result · 2011-06-30Clinical Trial Update: Codeine in Sickle Cell Disease [Phase 1, Phase 2]
The clinical trial update reports completion of Phase 1 and Phase 2 studies evaluating codeine in patients with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2011-06-06Clinical Trial Update: Sildenafil Therapy for Pulmonary Hypertension and Sickle Cell Disease [Phase 2]
Phase 2 clinical trial evaluating sildenafil therapy for sickle cell disease and pulmonary hypertension has been terminated; results have be…
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CLINICAL_TRIALS trial_result · 2011-05-02Clinical Trial Update: Study of Deferasirox Relative to Subcutaneous Deferoxamine in Sickle Cell Disease Patients [Phase 2]
Phase 2 trial comparing deferasirox with subcutaneous deferoxamine in patients with sickle cell disease and iron overload; results were post…
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CLINICAL_TRIALS trial_result · 2011-05-02Clinical Trial Update: Expanded Access of Deferasirox to Patients With Congenital Disorders of Red Blood Cells and Chronic Iron Overload [Phase 3]
This Phase 3 expanded-access update describes deferasirox use for patients with congenital disorders of red blood cells and chronic iron ove…
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CLINICAL_TRIALS research · 2011-02-23Clinical Trial Update: Sickle Cell Disease and Endothelial Progenitor Cells (EPCs)
An update on a completed clinical trial investigating endothelial progenitor cells in patients with Sickle Cell Anemia.
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CLINICAL_TRIALS trial_result · 2011-01-20Clinical Trial Update: Evaluation of the Safety, Tolerability, Pharmacokinetics (PK) and Effects on Liver Iron Concentration of ICL670 Relative to Deferoxamine(DFO). [Phase 2]
Phase 2 trial evaluating safety, tolerability, PK and effects on liver iron concentration of ICL670 relative to deferoxamine in sickle cell …
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CLINICAL_TRIALS research · 2010-11-18Clinical Trial Update: MACS Study - Microparticles and Coagulation in Sickle Cell Disease
Clinical trial update for the MACS study investigating microparticles and coagulation in Sickle Cell Disease; status is unknown.
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CLINICAL_TRIALS research · 2010-10-25Clinical Trial Update: A Randomized Trial of LOVAZA in Pediatric Sickle Cell Disease (SCD) [Phase 2]
A Phase 2 randomized trial evaluating Lovaza (omega-3 fatty acids) in pediatric sickle cell disease is underway; current status is not discl…
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CLINICAL_TRIALS trial_result · 2010-09-14Clinical Trial Update: Spectralis HRA+OCT Imaging of the Retina With Autofluorescence in Sickle Cell Disease
Completed clinical trial evaluating retinal imaging with Spectralis HRA+OCT autofluorescence in patients with sickle cell disease.