Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2018-07-12Clinical Trial Update: Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital. [NA]
A completed clinical trial update surveying sickle cell disease patients to evaluate the transition between two hospitals and assess the qua…
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CLINICAL_TRIALS withdrawal · 2018-07-05Clinical Trial Update: Imatinib and Carvedilol for High Blood Pressure in the Lungs in Adults With Sickle Cell Disease [Phase 1]
Phase 1 clinical trial of imatinib and carvedilol for pulmonary hypertension in adults with sickle cell disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-06-28Clinical Trial Update: The Brigance Assessment Of Individual Neurodevelopment In Young Children With Sickle Cell Disease- 2
This is a completed clinical trial update regarding the Brigance assessment of neurodevelopment in young children with sickle cell disease, …
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CLINICAL_TRIALS withdrawal · 2018-06-21Clinical Trial Update: A Study of Oral L-citrulline in Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial of oral L-citrulline for sickle cell disease has been withdrawn, halting any further enrollment.
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CLINICAL_TRIALS withdrawal · 2018-06-21Clinical Trial Update: A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease [Phase 1]
A Phase 1 pilot trial evaluating azithromycin prophylaxis to prevent acute chest syndrome in sickle cell disease has been withdrawn.
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease [NA]
This clinical trial update reports results from a completed study evaluating patient-provider tools to improve the transition from pediatric…
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CLINICAL_TRIALS research · 2018-06-15Clinical Trial Update: Sickle Cell Disease (SCD) Decision Aid [NA]
A clinical trial update describes a decision aid for sickle cell disease sponsored by Emory University, and the study status is completed.
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease
A NICHD-sponsored clinical trial on fertility preservation for women undergoing gonadotoxic therapy or hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease
This update summarizes results from a completed study assessing the prevalence of problematic use of an equimolar mixture of oxygen and nitr…
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CLINICAL_TRIALS research · 2018-05-25Clinical Trial Update: Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose
Clinical trial update from Cardiologie et Développement regarding sickle cell anemia and sickle cell disease. The trial status is listed as …
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CLINICAL_TRIALS withdrawal · 2018-05-24Clinical Trial Update: Safety and Pharmacokinetics of SANGUINATE™ in Sickle Cell Disease (SCD) Patients
A clinical trial evaluating SANGUINATE for sickle cell disease has been withdrawn. The document summarizes safety and pharmacokinetics consi…
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients [Phase 2]
A Phase 2 trial evaluating SANGUINATE for treatment of vaso-occlusive crisis in adults with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis [Phase 2]
This ClinicalTrials.gov entry reports the completion of a Phase 2 study evaluating SANGUINATE for treatment of vaso-occlusive crisis in sick…
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FDA approval · 2018-05-11FDA Approved: JADENU — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for JADENU (deferasirox) from Novartis Pharmaceuticals Corporation, expanding its labeling for iron …
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I
Phase I trial evaluating a self-management intervention for youth with sickle cell disease and their families has completed.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease [Phase 2]
Phase II pharmacokinetic/pharmacodynamic dose-ranging study of ticagrelor in pediatric patients with sickle cell disease completed with resu…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Ketamine Infusion for Acute Sickle Cell Crisis in the Emergency Department [NA]
A clinical trial investigating ketamine infusion for acute pain in sickle cell crisis in the emergency department has been terminated.
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CLINICAL_TRIALS research · 2018-05-04Clinical Trial Update: Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG
This entry reports a completed ancillary transcranial Doppler ultrasound study conducted on subjects enrolled in the BABY HUG sickle cell tr…
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises [NA]
A clinical trial update describes a comprehensive care plan for pediatric patients with vaso-occlusive crises, sponsored by Valley Anesthesi…
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: A Phase II Trial of Regadenoson in Sickle Cell Anemia [Phase 2]
Phase II trial update for regadenoson in sickle cell anemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) [Phase 2]
Phase 2 trial evaluating bone marrow transplants in children with sickle cell disease.
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FDA approval · 2017-12-18FDA Approved: DROXIA — Supplemental Application (Waylis Therapeutics LLC)
FDA approved a supplemental application for DROXIA (hydroxyurea) submitted by Waylis Therapeutics LLC.
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial evaluating ticagrelor to reduce pain days in sickle cell disease has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease [Phase 1]
Phase 1 trial update on PF-04447943 with/without hydroxyurea in stable sickle cell disease examining safety, tolerability, PK, and PD.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe. [NA]
This update reports on a completed clinical trial in children with sickle cell disease in Martinique and Guadeloupe, investigating the epide…