Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2019-03-14Clinical Trial Update: Rifaximin to Modify the Disease Course in Sickle Cell Disease [Phase 2]
Phase 2 clinical trial investigating rifaximin to modify disease course in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2019-03-11Clinical Trial Update: Inhaled Mometasone to Reduce Painful Episodes in Patients With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial investigating inhaled mometasone to reduce painful episodes in sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2019-02-15Clinical Trial Update: PATient Navigator to rEduce Readmissions [NA]
A clinical trial update for a patient navigator aimed at reducing hospital readmissions, with completed status and results posted in 2019, i…
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: New Hemolysis Parameters in Sickle Cell Disease
This clinical trial update discusses the exploration of new hemolysis parameters in sickle cell disease. The trial status is listed as unkno…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Gaming Technology to Engage Adolescent Sickle Cell Patients in Pain Management [NA]
This report notes the completion of a clinical trial evaluating a gaming technology to engage adolescents with sickle cell disease in pain m…
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CLINICAL_TRIALS trial_result · 2019-02-06Clinical Trial Update: Pilot Study for Patients With Poor Response to Deferasirox [Phase 4]
Phase 4 pilot trial update on patients with poor response to Deferasirox.
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CLINICAL_TRIALS research · 2019-02-06Clinical Trial Update: Evaluation of Knowledge Among Adolescents With Sickle Cell Disease.
This clinical trial update reports on evaluating knowledge among adolescents with Sickle Cell Disease; the study status is completed.
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CLINICAL_TRIALS trial_result · 2019-02-05Clinical Trial Update: Effect of Atorvastatin on Endothelial Dysfunction and Albuminuria in Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating atorvastatin for endothelial dysfunction and albuminuria in sickle cell disease; study completed with results poste…
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: A Sickle CEll Disease ComplicatioN Trial [Phase 3]
Phase 3 trial evaluating Micelle BioPharma Inc's investigational product for sickle cell disease; current status is UNKNOWN.
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CLINICAL_TRIALS trial_result · 2019-01-31Clinical Trial Update: Dose-Finding Study of SC411 in Children With Sickle Cell Disease [Phase 2]
A Phase 2 dose-finding study of SC411 is being conducted in children with sickle cell disease; no results are provided in the update.
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CLINICAL_TRIALS trial_result · 2019-01-25Clinical Trial Update: Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions [Phase 4]
Phase 4 clinical trial update evaluating the use of Rejuvesol-washed red blood cells in sickle cell patients who require frequent transfusio…
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CLINICAL_TRIALS trial_result · 2019-01-02Clinical Trial Update: An Extension Study to Further Evaluate the Safety, Tolerability of GBT440 in Patients With Sickle Cell Disease Who Participated in the Study GBT440-001 [Phase 2]
An extension study to further evaluate safety and tolerability of GBT440 in sickle cell disease patients who participated in the prior trial…
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FDA approval · 2018-12-12FDA Approved: SIKLOS — Supplemental Application (Medunik)
FDA has approved a supplemental application for SIKLOS (hydroxyurea) filed by Medunik.
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CLINICAL_TRIALS trial_result · 2018-12-11Clinical Trial Update: Bi-Level Positive Airway Ventilation for Acute Chest Syndrome [NA]
Clinical trial update for Bi-Level Positive Airway Ventilation in Acute Chest Syndrome; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2018-10-09Clinical Trial Update: Decision Aid for Therapeutic Options In Sickle Cell Disease [NA]
A completed clinical trial evaluating a decision aid to support therapeutic options for sickle cell disease.
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CLINICAL_TRIALS trial_result · 2018-10-01Clinical Trial Update: Novel Use Of Hydroxyurea in an African Region With Malaria [Phase 3]
Phase 3 trial assessing novel use of hydroxyurea in Africans with sickle cell disease; results completed and posted in 2018.
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CLINICAL_TRIALS withdrawal · 2018-09-26Clinical Trial Update: Ketamine Sickle Cell Disease [Phase 3]
A Phase 3 clinical trial evaluating ketamine for sickle cell disease and chronic pain has been withdrawn from the study list.
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CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children [Phase 4]
Phase 4 trial comparing intranasal fentanyl to intravenous morphine for severe painful sickle cell crises in children has completed.
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CLINICAL_TRIALS trial_result · 2018-09-24Clinical Trial Update: tDCS Associated With Peripheral Electrical Stimulation for Pain Control in Individuals With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial investigating transcranial direct current stimulation (tDCS) with peripheral electrical stimulation for pain control …
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CLINICAL_TRIALS trial_result · 2018-09-12Clinical Trial Update: Preventing Stroke Triggers in Children With Sickle Cell Anaemia in Mulago Hospital, Kampala (PREST ): a Randomized Control Trial [Phase 2, Phase 3]
Randomized control trial investigating stroke prevention triggers in children with sickle cell anaemia at Mulago Hospital, Kampala (PREST) a…
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CLINICAL_TRIALS trial_result · 2018-08-21Clinical Trial Update: CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant [Phase 2]
Phase 2 clinical trial update on CD34+ selection for partially matched family or matched unrelated adult donor transplants in leukemia and l…
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CLINICAL_TRIALS trial_result · 2018-08-06Clinical Trial Update: Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs [Phase 2]
Phase 2 trial evaluating allogeneic hematopoietic cell transplantation from matched unrelated donor with reduced-intensity conditioning and …
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CLINICAL_TRIALS trial_result · 2018-07-27Clinical Trial Update: Comparison of Two Methods of Transfusion for Stroke Prevention in Sickle Cell
A completed study comparing two transfusion strategies for preventing stroke in people with sickle cell disease.
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CLINICAL_TRIALS withdrawal · 2018-07-26Clinical Trial Update: Risk Factors for Allo-immunization in Sickle Cell Disease
The clinical trial NCT03401125 investigating risk factors for allo-immunization in sickle cell disease has been withdrawn.
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CLINICAL_TRIALS withdrawal · 2018-07-16Clinical Trial Update: A Phase Ib Study of NVX-508 in Sickle Cell Disease [Phase 1]
The Phase Ib trial of NVX-508 in sickle cell disease has been withdrawn.