Sickle Cell Disease
📧 Sign up to get email alerts when something new happens for Sickle Cell Disease.
Sign up freeTop drugs studied for this disease
-
CLINICAL_TRIALS trial_result · 2020-09-29Clinical Trial Update: Losartan to Reverse Sickle Nephropathy [Phase 2]
A Phase 2 trial evaluating losartan for reversing sickle cell nephropathy has completed enrollment with results posted in 2020.
-
CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Niacin to Improve Blood Flow in People With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial update investigating niacin to improve血 flow in people with sickle cell disease.
-
CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol
Follow-up observational protocol for pediatric hydroxyurea (BABY HUG) Phase III trial in sickle cell anemia; study completed with results po…
-
CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study)
Follow-up study reporting long-term effects of hydroxyurea in children with sickle cell anemia (BABY HUG follow-up).
-
CLINICAL_TRIALS trial_result · 2020-08-19Clinical Trial Update: Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia [Phase 3]
Phase 3 trial investigating hydroxyurea for prevention of organ damage in children with sickle cell anemia; trial completed with posted resu…
- Want full summaries, importance scores, and drug timelines? Upgrade to Plus or Pro.
-
CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease [Phase 1, Phase 2]
Clinical trial update on vaporized cannabis for pain in sickle cell disease (Phase 1/2) completed with results posted.
-
CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II [Phase 3]
Phase 3 trial updating primary prevention of stroke in children with sickle cell disease in Sub-Saharan Africa has completed.
-
CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP [NA]
Clinical trial update for a bone marrow transplantation study in sickle cell disease and hemoglobin SC, terminated with results posted in 20…
-
CLINICAL_TRIALS withdrawal · 2020-07-15Clinical Trial Update: Study to Evaluate the Effect of Ticagrelor Versus Placebo in Reducing Vaso-Occlusive Crises Rate in Pediatric Patients With Sickle Cell Disease. [Phase 3]
A Phase 3 pediatric trial evaluating ticagrelor versus placebo for reducing vaso-occlusive crises in sickle cell disease was withdrawn.
-
CLINICAL_TRIALS research · 2020-07-09Clinical Trial Update: A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease [Phase 1, Phase 2]
Pilot phase 1/2 trial evaluating N-acetylcysteine in patients with sickle cell disease.
-
CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Steroid Treatment for Sickle Cell Pain Crisis [Phase 3]
Phase 3 trial evaluating steroid treatment for pain crisis in sickle cell disease; study terminated, results posted in 2020.
-
FDA approval · 2020-06-15FDA Approved: DEFERASIROX — Original Application (Amneal Pharmaceuticals NY LLC)
The FDA approved Amneal's generic deferasirox (Deferasirox) as an original ANDA for the treatment of transfusion-related iron overload in pa…
-
CLINICAL_TRIALS trial_result · 2020-05-13Clinical Trial Update: Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis [Phase 2]
Phase 2 trial update for GMI-1070 in sickle cell pain crisis (vaso-occlusive crisis) has completed.
-
FDA approval · 2020-04-22FDA Approved: ENDARI — Supplemental Application (Emmaus Medical, Inc.)
FDA approved a supplemental application for ENDARI (L-glutamine) from Emmaus Medical, Inc., updating its regulatory status.
-
CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients [Phase 1]
Phase 1 clinical trial updating peripheral blood stem cell collection in sickle cell disease patients; study completed with results posted i…
-
CLINICAL_TRIALS trial_result · 2020-04-16Clinical Trial Update: Self-Management for Youth and Families Living With SCD - SMYLS [NA]
Clinical trial update on a self-management program for youth and families living with sickle cell disease; study completed with results post…
-
FDA approval · 2020-04-13FDA Approved: DEFERASIROX — Supplemental Application (Xiromed, LLC)
The FDA approved a supplemental application for deferasirox filed by Xiromed, LLC under an ANDA.
-
CLINICAL_TRIALS trial_result · 2020-04-13Clinical Trial Update: The Effect of Rivaroxaban in Sickle Cell Disease [Phase 2]
Phase 2 clinical trial assessing rivaroxaban in sickle cell disease has completed with results posted.
-
CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: Vitamin D Supplementation in Children With Sickle Cell Disease [Phase 3]
Phase 3 trial evaluating vitamin D supplementation in children with sickle cell disease has completed.
-
CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: European Sickle Cell Disease Cohort - Hydroxyurea
A completed European cohort study evaluating hydroxyurea for sickle cell disease with results posted in 2020.
-
CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Apixaban in Patients With Sickle Cell Disease [Phase 3]
Phase 3 trial update for apixaban in sickle cell disease was terminated; results have been posted.
-
CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease [Phase 1, Phase 2]
A completed early-phase study evaluating the safety and efficacy of LentiGlobin BB305 in transfusion-dependent beta-thalassemia and sickle c…
-
CLINICAL_TRIALS trial_result · 2020-02-20Clinical Trial Update: Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas [Phase 3]
Phase 3 trial updating hydroxyurea therapy in children with sickle cell disease in malaria-endemic areas has completed.
-
EMA withdrawal · 2020-02-11EMA Application withdrawn: Xyndari — Emmaus Medical Europe Ltd
EMA withdrew the application for Xyndari by Emmaus Medical Europe Ltd in the orphan medicine program for anemia and sickle cell disease.
-
CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises [Phase 2]
Phase 2 clinical trial evaluating safety and impact of SelG1 with or without hydroxyurea in sickle cell disease patients experiencing pain c…