Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients
A completed clinical trial evaluating strategies to improve red blood cell transfusions for chronically transfused patients with sickle cell…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: "Association of Proteinuria and Progression of Kidney Dysfunction in Sickle Cell Disease"Disease
A completed clinical trial evaluating the relationship between proteinuria and progression of kidney dysfunction in sickle cell disease, foc…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: LEARNER- Low dosE AspiRiN prEterm tRial (Angola) [Phase 1, Phase 2]
This clinical trial update describes the LEARNER trial evaluating low-dose aspirin for sickle cell disease and pregnancy-related complicatio…
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD [Phase 2]
A Phase 2 clinical trial is evaluating haploidentical T-depleted stem cell transplantation in patients with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Study Aimed to Assess the Needs of Subjects With Sickle Cell Disease and Healthcare Professionals Managing Sickle Cell Disease Patients in Selected Nigerian Centres
A completed clinical trial conducted in selected Nigerian centers to assess the needs of individuals with sickle cell disease and the health…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)
This clinical trial update from the Sickle Cell Disease Implementation Consortium outlines the interventions specified for sickle cell disea…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Desmopressin for Bedwetting in Children With SCD [Phase 4]
A Phase 4 trial evaluating desmopressin for bedwetting in children with sickle cell disease was terminated, with results posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT [NA]
The HABIT trial evaluating hydroxyurea adherence in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Voxelotor Neurocognitive Function Study [Phase 3]
Phase 3 trial evaluating voxelotor for neurocognitive function in sickle cell disease was terminated; results were posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: PINPOINT: Gaming Technology for SCD Pain [NA]
A completed clinical trial evaluated PINPOINT gaming technology for pain management in sickle cell disease; results were posted on May 1, 20…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment [NA]
A terminated clinical trial evaluated an implementation strategy for delivering routine mental health screening and treatment for patients w…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Hematopoietic Stem Cell Transplant for Sickle Cell Disease [Phase 1]
Phase 1 trial update on hematopoietic stem cell transplantation for sickle cell disease, with the study status listed as completed.
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: Low Systemic/High Local Exercise Load in Peds SCD [NA]
The update describes a pediatric sickle cell disease study investigating low systemic and high local exercise load, sponsored by the Univers…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC) [Phase 2]
Phase 2 pharmacokinetics and pharmacodynamics study of crizanlizumab (SEG101) in sickle cell disease patients with vaso-occlusive crisis; th…
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: A Study of SHP655 (rADAMTS13) in Sickle Cell Disease [Phase 1]
Phase 1 trial update for SHP655 (rADAMTS13) in sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Management of Severe Acute Malnutrition in SCD, in Northern Nigeria [Phase 2]
Phase 2 clinical trial evaluating management of severe acute malnutrition in sickle cell disease patients in Northern Nigeria has completed …
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) [Phase 4]
Phase 4 trial update on enhancing preventive therapy for malaria in children with sickle cell anemia in East Africa; results have been poste…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: Sickle Cell Anemia WE CARE [NA]
A completed clinical trial (NCT03716726) investigating sickle cell disease, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias [Phase 1, Phase 2]
A phased clinical trial update exploring improvements in bone marrow transplantation for patients with severe congenital anemias, including …
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: COVID-19 Testing in Underserved and Vulnerable Populations [NA]
Clinical trial with terminated status related to COVID-19 testing in underserved populations; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating red blood cell half-life in patients with and without sickle cell disease; study completed with resu…
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Therapeutic Anticoagulation Strategy for Acute Chest Syndrome [Phase 3]
A Phase 3 trial evaluating therapeutic anticoagulation strategy for Acute Chest Syndrome in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias [Phase 4]
Phase 4 trial assessing long-term safety and efficacy of Ferriprox in iron-overloaded patients, including those with sickle cell disease and…
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Non-Myeloablative Conditioning and Bone Marrow Transplantation [NA]
Clinical trial update involving non-myeloablative conditioning and bone marrow transplantation for sickle cell disease and related hemoglobi…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Glutamine Role in Preventing Vaso-occlusive Crisis Among SCD Patients [Phase 4]
Phase 4 clinical trial assessing glutamine to prevent vaso-occlusive crises in sickle cell disease has completed.