Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Nitrous Oxide Analgesia Vaso-occlusive Crisis [Phase 2]
Phase 2 trial evaluating nitrous oxide analgesia for vaso-occlusive crisis in sickle cell disease has completed, with results posted on 2024…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Low-Interventional Study of an Electronic Sickle Cell Disease Patient Reported Outcomes in Sickle Cell Participants
A low-interventional study evaluating electronic patient-reported outcomes in sickle cell disease participants has been terminated.
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study to Learn About Sickle Cell Disease In Adult Patients
Pfizer-sponsored clinical trial in adults with sickle cell disease has completed.
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: Role of Transcranial Doppler and Magnetic Resonance Angiography for Future Management of Sickle Cell Anemia CNS.
This clinical trial update discusses the potential role of Transcranial Doppler and Magnetic Resonance Angiography in managing CNS complicat…
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases [Phase 2]
This Phase 2 clinical trial update reports the termination of a haploidentical hematopoietic stem cell transplantation study using reduced-i…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Lung Ultrasound in Pediatric Acute Chest Syndrome
A pediatric trial evaluating lung ultrasound for acute chest syndrome in sickle cell disease is currently recruiting.
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FDA approval · 2024-07-08FDA Approved: L-GLUTAMINE — Original Application (ANI Pharmaceuticals, Inc.)
FDA approved ANI Pharmaceuticals' original ANDA for L-Glutamine, authorizing a generic version of the drug.
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Virtual Reality as an Adjuvant Therapy for Sickle Cell Vaso-Occlusive Crisis in the Pediatric Emergency Department [NA]
A completed clinical trial evaluating virtual reality as an adjuvant therapy for pediatric sickle cell vaso-occlusive crisis in the emergenc…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease [NA]
A completed clinical trial evaluating a technology platform that applies patient-centered guidelines to improve health care for adults with …
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FDA approval · 2024-06-26FDA Approved: ADAKVEO — Supplemental Application (Novartis Pharmaceuticals Corporation)
FDA approved a supplemental application for ADAKVEO (crizanlizumab) submitted by Novartis Pharmaceuticals Corporation.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial [NA]
The HABIT trial evaluating adherence to hydroxyurea in sickle cell disease has completed, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Microvascular Blood Flow in Sickle Cell Anemia [NA]
A clinical trial evaluating microvascular blood flow in people with sickle cell disease/sickle cell anemia has completed and posted its resu…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India
This document notes the termination of a prospective, observational study evaluating crizanlizumab in sickle cell disease patients in Middle…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Validating Pain Scales in Children and Young Adults
National Cancer Institute completed a clinical trial focused on validating pain scales in children and young adults with sickle cell disease…
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease [NA]
Clinical trial update indicates ongoing recruitment for a pediatric-to-adult care transition program in patients with Sickle Cell Disease.
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: ASH Research Collaborative Data Hub
The ASH Research Collaborative Data Hub trial is currently enrolling by invitation for Sickle Cell Disease and Multiple Myeloma. This entry …
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease [Phase 1]
This Phase 1 clinical trial evaluated abatacept as prophylaxis against graft-versus-host disease after hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Stem Cell Transplant in Sickle Cell Disease and Thalassemia [Phase 2]
Phase 2 clinical trial update on hematopoietic stem cell transplantation for sickle cell disease and beta-thalassemia; the study is currentl…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Mobile-Directly Observed Therapy on Adherence to Hydroxyurea [Phase 2]
Phase 2 trial evaluating mobile directly observed therapy to improve adherence to hydroxyurea in patients with sickle cell disease; the stud…
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD) [Phase 1]
Pfizer completed a Phase 1 study evaluating single-dose and multiple-dose regimens of GBT021601-012 in participants with Sickle Cell Disease…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease [Phase 2]
A Phase 2 trial evaluating the effect of crizanlizumab on kidney function in patients with chronic kidney disease caused by sickle cell dise…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada [NA]
A completed clinical trial evaluated low-cost testing methods for detecting sickle cell disease and beta-thalassemia in Nepal and Canada, wi…
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease [NA]
A clinical study is evaluating BRL-101 for treating sickle cell disease, assessing safety and efficacy, with recruitment not yet started.
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Effect of NUV001 Supplementation in Patients Suffering From Sickle Cell Disease (SCD) [NA]
This document notes an active-not-recruiting clinical trial evaluating NUV001 supplementation in patients with Sickle Cell Disease.
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Safety and Efficacy of Orally Administered NUV001 Nutraceutical Supplement in Sickle Cell Disease Patients [NA]
This document provides an update on a clinical trial assessing the safety and efficacy of the orally administered NUV001 nutraceutical suppl…