Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Exploration of the Parameters Influencing the Effort Limitation of Patients Suffering From Homozygous Sickle Cell Anemia
A completed clinical trial from Assistance Publique - Hôpitaux de Paris investigating factors that limit exercise capacity in patients with …
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Longitudinal Changes in Exercise Capacity in Children and Young Adults With Sickle Cell Anemia
This clinical trial update reports on longitudinal changes in exercise capacity among children and young adults with sickle cell disease and…
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CLINICAL_TRIALS trial_result · 2024-12-18Clinical Trial Update: Sickle Cell Pro-Inflammatory Response to Interval Training Study
The clinical trial investigating the pro-inflammatory response to interval training in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-12-13Clinical Trial Update: Building Adaptive Coping and Knowledge to Improve Daily Life [NA]
A clinical trial investigating an adaptive coping and knowledge program for individuals with Sickle Cell Disease has completed, with results…
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises [Phase 3]
Pfizer's Phase 3 study evaluating a single dose of inclacumab to reduce hospital readmissions in sickle cell disease patients with recurrent…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease [Phase 3]
A Phase 3 clinical trial evaluating BB305 Lentiviral Vector gene therapy for sickle cell disease is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Nonmyeloablative Stem Cell Transplant in Children with Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor [Phase 2]
A Phase 2 nonmyeloablative stem cell transplant trial in children with sickle cell disease using a major ABO-incompatible matched sibling do…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Minocycline in Neurocognitive Outcomes - Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial from the University of Cincinnati is investigating whether minocycline can improve neurocognitive outcomes in sickl…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Community Health Workers and mHealth for Sickle Cell Disease Care [NA]
A completed clinical trial evaluating the impact of community health workers and mobile health tools on care for patients with sickle cell d…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease [NA]
Terminated clinical trial evaluating haploidentical hematopoietic stem cell transplantation for severe sickle cell disease, with results pos…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Acupuncture for Pain in Sickle Cell Disease [NA]
A clinical trial evaluating acupuncture for pain in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: AB1 in Adult Patients with Sickle Cell Disease (SCD) [Phase 1, Phase 2]
A Phase 1/2 study of AB1 in adults with Sickle Cell Disease has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure [Phase 2]
Phase 2 trial update examining a nonmyeloablative peripheral blood stem cell transplantation approach for sickle cell disease and beta-thala…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: SCRIPT: Sickle Cell Risk in Pregnancy Tool
SCRIPT is a study evaluating a sickle cell risk in pregnancy tool. Enrollment is by invitation.
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial update evaluating early HLA-matched sibling hematopoietic stem cell transplantation for sickle cell disease. The tr…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Voxelotor CYP and Transporter Cocktail Interaction Study [Phase 1]
Pfizer completed a Phase 1 pharmacokinetic interaction study of voxelotor with CYP and transporter substrates; results have been posted.
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Expanded Access Protocol for Adults and Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment Options
Pfizer's Expanded Access Protocol for adults and pediatric patients with sickle cell disease who have no alternative treatment options is no…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease [NA]
This clinical trial update reports an mHealth strategy intended to improve medication adherence in adolescents with sickle cell disease; the…
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Age of Blood in Sickle Cell Transfusion [Phase 2, Phase 3]
Results from a Phase 2/Phase 3 trial evaluating the impact of the age of transfused red blood cells on outcomes in sickle cell disease have …
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED [Phase 3]
A Phase 3 trial evaluating intranasal ketamine for pain control during vaso-occlusive episodes in children with sickle cell disease was term…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy
Completed clinical trial investigating how red blood cell characteristics, angiogenesis, viscosity, and oxygenation relate to the pathophysi…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease [Phase 1, Phase 2]
A clinical trial update indicates that BAH243, a lentiviral vector gene therapy, is being investigated for sickle cell disease in Phase 1/Ph…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Cerebrovascular Reserve and White Matter Disease in Patients with Chronic Anemia
Completed clinical trial assessing cerebrovascular reserve and white matter disease in patients with chronic anemia due to thalassemia or si…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Real World Patient Characteristics and Treatment Patterns From Crizanlizumab Use: Preliminary Analysis From Select Sickle Cell Centers
This document reports a preliminary real-world analysis of patient characteristics and treatment patterns among crizanlizumab users in selec…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery Registry
This completed registry study describes the characteristics and treatment patterns of patients with sickle cell disease in the Globin Resear…