Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria [NA]
A clinical trial update indicates ongoing recruitment in Nigeria for a study evaluating increased adoption of hydroxyurea to manage sickle c…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients With Pulmonary Arterial Hypertension (PAH) [Phase 3]
A Phase 3 trial evaluating the efficacy and safety of bosentan in sickle cell disease patients with pulmonary arterial hypertension was term…
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CLINICAL_TRIALS trial_result · 2025-02-04Clinical Trial Update: Efficacy and Safety of Bosentan in Sickle Cell Disease (SCD) Patients Diagnosed With Pulmonary Hypertension (PH) [Phase 3]
Phase 3 trial evaluating Bosentan in sickle cell disease patients with pulmonary hypertension was terminated, with the update focusing on ef…
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CLINICAL_TRIALS other · 2025-02-03Clinical Trial Update: A Study of Patients Having Pulmonary Hypertension Associated With Sickle Cell Disease and Completing an ASSET Study [Phase 3]
This clinical trial update notes that the Phase 3 ASSET study in patients with pulmonary hypertension associated with sickle cell disease ha…
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CLINICAL_TRIALS trial_result · 2025-01-31Clinical Trial Update: A Study Evaluating the Safety and Efficacy of EDIT-301 in Participants With Severe Sickle Cell Disease (RUBY) [Phase 1, Phase 2]
This document provides an update on RUBY, a Phase 1/2 clinical trial evaluating EDIT-301 for severe sickle cell disease, focusing on safety …
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Evaluation of Impact of Disease on Quality of Life, Education and Socio-professional Integration of Adults and Parents of Children Living with Sickle- Cell Disease in France
This completed clinical trial in France evaluated how sickle cell disease affects quality of life, education, and socio-professional integra…
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CLINICAL_TRIALS trial_result · 2025-01-27Clinical Trial Update: Steroid Injection for Sickle Cell Arthropathy Pain Therapy
A completed clinical trial evaluating the use of corticosteroid injections to treat pain associated with sickle cell arthropathy.
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CLINICAL_TRIALS other · 2025-01-27Clinical Trial Update: Kidney Function in Sickle Cell Anemia
An ongoing trial led by Kenneth Ataga is examining kidney function in people with Sickle Cell Disease and chronic kidney failure. The study …
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Sickle-cell Disease Registry of the GPOH
Registry-style clinical trial entry for Sickle cell disease under the GPOH, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-24Clinical Trial Update: Sleep and Pain in Sickle Cell Disease [NA]
A clinical trial examining sleep and pain in sickle cell disease has completed.
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FDA approval · 2025-01-22FDA Tentative Approval: SIKLOS — Supplemental Application (Medunik)
FDA tentatively approved Medunik's supplemental application for Siklos (hydroxyurea), indicating approvable status for a hydroxyurea product…
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation
This clinical trial investigates how biological phenotype relates to clinical severity in sickle cell disease and its impact on blood coagul…
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain [NA]
Ongoing clinical trial evaluating virtual reality as adjunct therapy for vaso-occlusive pain in sickle cell disease, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-13Clinical Trial Update: Safety, Efficacy, Pharmacokinetic, and Pharmacodynamic Study of ALXN1820 in Adult Participants With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial evaluating safety, efficacy, pharmacokinetics, and pharmacodynamics of ALXN1820 in adults with sickle cell disease; t…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease [NA]
A clinical trial update shows a feasibility and efficacy study of attentional-control training in sickle cell disease is currently recruitin…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Evaluation of the Impact of Red Blood Cell Exchange on Thrombo-inflammation in Sickle Cell Disease
This clinical trial evaluates whether red blood cell exchange can reduce thrombo-inflammation in sickle cell disease; recruitment has not ye…
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CLINICAL_TRIALS trial_result · 2025-01-09Clinical Trial Update: Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE) [Phase 3]
Phase 3 trial update (PIPSICKLE) evaluating low-dose aspirin to prevent intrauterine growth restriction and preeclampsia in pregnancies affe…
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: An Indian Multi-centric Phase IV Study to Assess the Safety of Crizanlizumab in Sickle Cell Disease Patients [Phase 4]
Phase IV multicenter Indian study evaluating the safety of crizanlizumab in sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2025-01-08Clinical Trial Update: A GBT021601 ADME Microtracer Study in Healthy Volunteers [Phase 1]
Pfizer completed a Phase 1 ADME microtracer study of GBT021601 in healthy volunteers; results have been posted.
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia [Phase 2, Phase 3]
A Phase 2/3 trial is evaluating pharmacokinetic-guided dosing of hydroxyurea in patients with moderate to severe sickle cell disease.
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Pulmonary Functions in Sickle Cell Disease: Response to Acu-TENS [NA]
Acu-TENS is being studied in a clinical trial to evaluate pulmonary function in individuals with sickle cell disease; the study is currently…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Pilot Study on the Value of Bedside Pleuropulmonary Ultrasound in Patients With Sickle Cell Disease Presenting With Vaso-occlusive Crisis
A pilot study is evaluating the value of bedside pleuropulmonary ultrasound in patients with sickle cell disease presenting with a vaso-occl…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD. [NA]
Clinical trial update documenting an ongoing study on how adherence to hydroxyurea relates to health-related quality of life and barriers in…
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CLINICAL_TRIALS trial_result · 2024-12-24Clinical Trial Update: COVID-19 Vaccination Hesitancy in Adults With Sickle Cell Disease [NA]
A completed clinical trial update from Duke University examining COVID-19 vaccination hesitancy among adults with Sickle Cell Disease (NCT05…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Haploidentical Hematopoietic Stem Cell Transplantation [Phase 1]
Phase 1 trial update reports the completion of a haploidentical hematopoietic stem cell transplantation study led by Catherine Bollard, inve…