Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Pressure Pain Tolerance in Relation to Balance and Strength in Children [NA]
A clinical trial studying pressure pain tolerance in relation to balance and strength in children with Sickle Cell Anemia; recruitment is on…
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Escalation of Plerixafor for Mobilization of CD34+ Hematopoietic Progenitor Cells and Evaluation of Globin Gene Transfer in Patients With Sickle Cell Disease [Phase 1]
Phase 1 trial in sickle cell disease evaluates escalating doses of Plerixafor to mobilize CD34+ hematopoietic progenitor cells and assesses …
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: ORCHARD- Optimising Home Assessment of Rural Patients [NA]
ORCHARD, a trial on Optimising Home Assessment of Rural Patients, has completed; the update provides no trial results in this notice.
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CLINICAL_TRIALS trial_result · 2025-03-27Clinical Trial Update: Sickle Cell Hemoglobinopathies and Bone Health
Clinical trial update indicating that the Sickle Cell Hemoglobinopathies and Bone Health study sponsored by UConn Health is currently active…
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CLINICAL_TRIALS trial_result · 2025-03-24Clinical Trial Update: Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. [NA]
Completed clinical trial evaluating the combined use of a respiratory broad panel multiplex PCR and procalcitonin to reduce antibiotic expos…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Glucose Metabolism in Sickle Cell Disease
ClinicalTrials.gov update notes the status of a study evaluating glucose metabolism in sickle cell disease, including the conditions Sickle …
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CLINICAL_TRIALS trial_result · 2025-03-20Clinical Trial Update: Long-term Follow-up of Subjects with Sickle Cell Disease Treated with Ex Vivo Gene Therapy
Long-term follow-up of subjects with Sickle Cell Disease treated with an ex vivo gene therapy; enrollment by invitation is ongoing.
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Phenotypic and Transcriptomic Description of Megakaryocytes in Sickle Cell Patient
This clinical trial update describes the phenotypic and transcriptomic characteristics of megakaryocytes in patients with sickle cell diseas…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department [Phase 3]
Phase 3 trial evaluating analgesia with parecoxib versus morphine in emergency department patients with sickle cell disease experiencing a c…
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CLINICAL_TRIALS withdrawal · 2025-03-19Clinical Trial Update: THromboprophylaxis In Sickle Cell Disease With Central Venous Catheters (THIS) [Phase 3]
A Phase 3 trial evaluating thromboprophylaxis in sickle cell disease patients with central venous catheters has been terminated.
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Synthetic Generation of Hematological Data Over Federated Computing Frameworks: SCD Use Case
A clinical trial update describing a study on synthetic generation of hematologic data across federated computing frameworks, using Sickle C…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Efficacy and Safety of Rivipansel (GMI-1070) in the Treatment of Vaso-Occlusive Crisis in Hospitalized Subjects With Sickle Cell Disease [Phase 3]
A Phase 3 trial evaluating rivipansel (GMI-1070) for treating vaso-occlusive crisis in hospitalized patients with sickle cell disease has co…
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CLINICAL_TRIALS trial_result · 2025-03-11Clinical Trial Update: Efficacy and Safety of Tocilizumab for Acute Chest Syndrome Treatment in Patients With Sickle Cell Disease [Phase 3]
This Phase 3 clinical trial is evaluating the efficacy and safety of tocilizumab for treating acute chest syndrome in patients with sickle c…
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CLINICAL_TRIALS trial_result · 2025-03-10Clinical Trial Update: A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism [Phase 2]
Phase 2 trial evaluating crizanlizumab for sickle cell disease-related priapism has completed, with results posted.
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.
A completed clinical trial update examining links between cognitive function and clinical, biological, and neuroradiological outcomes in adu…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: A Socio-ecological Approach for Improving Self-management in Adolescents With SCD [Phase 2]
Phase 2 clinical trial update on a socio-ecological intervention to improve self-management in adolescents with sickle cell disease; current…
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies [NA]
A hematopoietic stem cell transplant trial for high-risk hemoglobinopathies has been terminated; the conditions studied include sickle cell …
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CLINICAL_TRIALS other · 2025-02-25Clinical Trial Update: Pilot Study PBSCT with TCRab Depletion for Hemoglobinopathies [NA]
Pilot study of peripheral blood stem cell transplant with TCRαβ depletion for hemoglobinopathies; the trial is currently active but not recr…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications [NA]
A completed clinical trial tested a mobile app–based cognitive behavioral therapy plus real-time pain management for people with sickle cell…
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CLINICAL_TRIALS trial_result · 2025-02-18Clinical Trial Update: Study to Assess Efficacy and Safety of VIT-2763 (Vamifeport) in Subjects With Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating the efficacy and safety of vamifeport (VIT-2763) in sickle cell disease has completed and results have been posted.
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19
This clinical trials registry update reports completion of the ERN-EuroBloodNet registry documenting patients with rare red blood cell defec…
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CLINICAL_TRIALS trial_result · 2025-02-14Clinical Trial Update: COVID-19 Vaccine Response in Sickle Cell Disease
A completed clinical trial evaluated the immune response to a COVID-19 vaccine in people with Sickle Cell Disease; results were posted on 20…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring [NA]
A clinical trial investigating therapeutic pharmacological monitoring to optimize hydroxyurea treatment for sickle cell disease.
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease [NA]
The update indicates ongoing recruitment for a study assessing feasibility and acceptability of digital cognitive rehabilitation in sickle c…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Long-term Endurance Training in Sickle Cell Disease Patients: Impact on Clinical Profile, Physical Fitness, and Quality of Life. [NA]
Clinical trial evaluating long-term endurance training in patients with sickle cell disease to assess impact on clinical profile, physical f…