Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: EXTEND EXpanding Treatment for Existing Neurological Disease [Phase 2]
A Phase 2 clinical trial evaluating an extended treatment approach for existing neurological disease in sickle cell anemia has completed.
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CLINICAL_TRIALS trial_result · 2025-08-22Clinical Trial Update: SACRED A Prospective Research Study to Reduce Stroke in Children With Sickle Cell Anemia [NA]
The SACRED A trial, a prospective study aimed at reducing stroke in children with sickle cell disease, has completed.
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CLINICAL_TRIALS trial_result · 2025-08-21Clinical Trial Update: Sickle Cell Disease, Hemechip
A completed clinical trial evaluating Hemechip for sickle cell disease conducted at University Hospitals Cleveland Medical Center.
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
This entry provides an update on a recruiting clinical trial evaluating the SCD BioChip, a biofluid chip technology for sickle cell disease.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Adapting the FACETS Program to Sickle Cell Disease [NA]
A clinical trial is adapting the FACETS program for sickle cell disease to address fatigue and related symptoms. The study is currently recr…
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CLINICAL_TRIALS trial_result · 2025-08-15Clinical Trial Update: Study to Evaluate the Effect of GBT440 in Pediatrics With Sickle Cell Disease [Phase 2]
Phase 2 pediatric trial evaluating GBT440 (voxelotor) for sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: The BENeFiTS Trial in Beta Thalassemia Intermedia [Phase 1, Phase 2]
The BENeFiTS trial is a Phase 1/2 study in beta-thalassemia intermedia and sickle cell disease that is currently enrolling by invitation, sp…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
This document provides an update on a phase 1/2 clinical trial evaluating CD34+ stem cell selection for patients receiving allogeneic stem c…
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CLINICAL_TRIALS other · 2025-08-14Clinical Trial Update: Reduced Intensity Transplantation for Severe Sickle Cell Disease [Phase 2]
A Phase 2 clinical trial evaluating reduced-intensity transplantation for severe sickle cell disease has been suspended. Sponsor: St. Jude C…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias [Phase 1, Phase 2]
This clinical trials update notes that a T-cell depleted alternative donor bone marrow transplant for sickle cell disease and other anemias …
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: A Safety and Efficacy Study Evaluating CTX001 in Subjects With Severe Sickle Cell Disease [Phase 2, Phase 3]
A safety and efficacy study of CTX001 in subjects with severe Sickle Cell Disease has completed Phase 2 and Phase 3 trials.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD) [Phase 1]
Phase 1 trial update describes a combination of Motixafortide and Natalizumab to mobilize CD34+ hematopoietic stem cells for gene therapies …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion [Phase 2]
A Phase 2 clinical trial evaluating allogeneic stem cell transplantation with alpha/beta T cell and CD19+ B cell depletion for malignant and…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease [Phase 2]
Clinical trial update for a Phase 2 study of haploidentical, T-cell depleted transplantation in high-risk sickle cell disease; the trial is …
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CLINICAL_TRIALS trial_result · 2025-08-05Clinical Trial Update: Sex Hormones and Inflammatory Biomarkers in Patients With Sickle Cell Disease
A completed clinical trial evaluating the relationship between sex hormones and inflammatory biomarkers in patients with sickle cell disease…
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Effects of the Contraceptive Implant in Women With Sickle Cell Disease [Phase 4]
Phase 4 clinical trial to assess the effects of the etonogestrel contraceptive implant in women with sickle cell disease. The study is curre…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait
A completed clinical trial update from NHLBI evaluating biomarkers related to venous thrombosis in people with sickle cell disease and sickl…
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CLINICAL_TRIALS trial_result · 2025-08-01Clinical Trial Update: Exploring Near Infrared Spectroscopy (NIRS) Technologies for Assessment of Muscle Physiology, Tissue Oxygenation, and Blood Flow in Patients With Sickle Cell Disease (SCD)
This completed clinical trial update describes using near-infrared spectroscopy to assess muscle physiology, tissue oxygenation, and blood f…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease [NA]
A clinical trial update indicates a stress and pain self-management mobile health app for adult outpatients with sickle cell disease is curr…
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Sickle Cell Disease Treatment With Arginine Therapy (STArT) Trial [Phase 3]
Phase 3 STArT trial evaluating arginine therapy for sickle cell disease has completed and results have been posted.
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CLINICAL_TRIALS trial_result · 2025-07-30Clinical Trial Update: Full Assessment of Clinical Transfusion Support
Clinical trial update noting the completion of a study on transfusion support in sickle cell anemia, with attention to malaria parasitaemia.
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CLINICAL_TRIALS trial_result · 2025-07-28Clinical Trial Update: Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions [NA]
Completed clinical trial results have been posted for the Peer i-Coaching program, evaluating activated self-management optimization in adol…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: High-flow Oxygen for Vaso-occlusive Pain Crisis [NA]
A clinical trial is evaluating high-flow oxygen for vaso-occlusive pain crisis in sickle cell disease. The study is currently recruiting in …
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CLINICAL_TRIALS trial_result · 2025-07-25Clinical Trial Update: Study of MGTA-145 and Plerixafor in Patients With Sickle Cell Disease [Phase 2]
A Phase 2 trial evaluating MGTA-145 in combination with Plerixafor for sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait
This clinical trial is studying bone loss, physical function, and frailty in older women with sickle cell trait, sponsored by UConn Health, …