Records containing: Sickle Cell Disease
This is the wording recorded or indexed by the source. An agency index term is not necessarily an authorised indication. Co-listed drug names are not linked to this term as a treatment relationship.
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CLINICAL_TRIALS study record update · 2025-07-09A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy of Voxelotor for the Treatment of Leg Ulcers in Patients With Sickle Cell Disease
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CLINICAL_TRIALS study record update · 2025-06-25Treatment of Sickle Cell Pain and Inflammation With Cannabidiol (SPICe)
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CLINICAL_TRIALS study record update · 2025-06-25Use of Macrolides in Acute Chest Syndrome: A Multicenter Retrospective Study
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CLINICAL_TRIALS study record update · 2025-06-22Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
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CLINICAL_TRIALS study record update · 2025-06-19Effect of MitoQ on Platelet Function and Reactive Oxygen Species (ROS) Generation in Patients With Sickle Cell Anemia
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CLINICAL_TRIALS study record update · 2025-06-18Hydroxyurea Optimization Through Precision Study (HOPS): A Prospective, Multi-center, Randomized Trial of Personalized, Pharmacokinetics-guided Dosing of Hydroxyurea Versus Standard Weight-based Dosing for Children With Sickle Cell Anemia.
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CLINICAL_TRIALS study record update · 2025-06-13Prevalence and Mapping of Sickle Cell Trait and Disease in Uganda
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CLINICAL_TRIALS study record update · 2025-06-13A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study of Voxelotor (GBT440) in Pediatric Participants With Sickle Cell Disease (HOPE Kids 2)
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CLINICAL_TRIALS study record update · 2025-06-08Kinetics of Donor Red Blood Cell Survival in Sickle Cell Disease
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CLINICAL_TRIALS study record update · 2025-06-03Molecular and Cellular Basis of Severe Forms of Dengue in Sickle Cell Patients
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CLINICAL_TRIALS study record update · 2025-06-03Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease
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CLINICAL_TRIALS study record update · 2025-06-03Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
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CLINICAL_TRIALS study record update · 2025-06-02An Open-Label Study to Evaluate the Safety and Efficacy of a Single Dose of Autologous CD34+ Human Hematopoietic Stem Cells Modified Using Transformer Base Editor in Participants With Severe Sickle Cell Disease
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CLINICAL_TRIALS study record update · 2025-05-29A Phase III, Multi-Center, Double-Blind, Placebo-Controlled, Randomized Study of Intravenous L-Citrulline in Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis in Children, Adolescents and Young Adults (6 to 21 Years)
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CLINICAL_TRIALS study record update · 2025-05-25Proof-of-concept Study of Nicotinamide and Oral Tetrahydrouridine (THU) and Decitabine to Treat High Risk Sickle Cell Disease
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CLINICAL_TRIALS study record update · 2025-05-23Role of Inflammasome in Platelet Activation in Sickle Cell Disease Patient
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CLINICAL_TRIALS study record update · 2025-05-23Safety and Efficacy of Prophylactic Defibrotide in Children, Adolescents, and Young Adults With Sickle Cell Disease or Beta Thalassemia Following MAC and Haploidentical Stem Cell Transplantation Utilizing CD34 Enrichment and T-Cell (CD3) Addback
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CLINICAL_TRIALS study record update · 2025-05-15A Phase 1a Study of IMR-687 in Healthy Adult Volunteers
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CLINICAL_TRIALS study record update · 2025-05-14Multicentre Randomized Double-blind Placebo-controlled Study to Evaluate the Effect on Albuminuria of 6 Months Treatment With Hydroxycarbamide (Siklos®) or a Placebo in Adults With Sickle Cell Disease:
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CLINICAL_TRIALS study record update · 2025-05-07Positron Emission Tomography (PET) Imaging of Vaso-occlusive Crisis(VOC) in Sickle Cell Disease (SCD).
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CLINICAL_TRIALS study record update · 2025-05-07A Phase II Study of Topical Sodium Nitrite in Patients With Sickle Cell and Leg Ulcers
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CLINICAL_TRIALS study record update · 2025-05-02RH Genotype Matched Red Cells for Patients With Sickle Cell Disease and Anti-D
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CLINICAL_TRIALS study record update · 2025-04-27Reduced Intensity Conditioning for Haploidentical Bone Marrow Transplantation in Patients With Symptomatic Sickle Cell Disease. (BMTCTN1507)
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CLINICAL_TRIALS study record update · 2025-04-20Home-Based Intervention for Chronic Pain in Adults With Sickle Cell Disease (HIPAS)
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CLINICAL_TRIALS study record update · 2025-04-18A Multi-Center, Phase 2 Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell (GRASP, BMT CTN 2001)