Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: A Study of SHP655 (rADAMTS13) in Sickle Cell Disease [Phase 1]
Phase 1 trial update for SHP655 (rADAMTS13) in sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Management of Severe Acute Malnutrition in SCD, in Northern Nigeria [Phase 2]
Phase 2 clinical trial evaluating management of severe acute malnutrition in sickle cell disease patients in Northern Nigeria has completed …
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CLINICAL_TRIALS trial_result · 2024-03-27Clinical Trial Update: Enhancing Preventive Therapy of Malaria In Children With Sickle Cell Anemia in East Africa (EPiTOMISE) [Phase 4]
Phase 4 trial update on enhancing preventive therapy for malaria in children with sickle cell anemia in East Africa; results have been poste…
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CLINICAL_TRIALS trial_result · 2024-03-26Clinical Trial Update: Sickle Cell Anemia WE CARE [NA]
A completed clinical trial (NCT03716726) investigating sickle cell disease, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-29Clinical Trial Update: Improving the Results of Bone Marrow Transplantation for Patients With Severe Congenital Anemias [Phase 1, Phase 2]
A phased clinical trial update exploring improvements in bone marrow transplantation for patients with severe congenital anemias, including …
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CLINICAL_TRIALS trial_result · 2024-02-28Clinical Trial Update: COVID-19 Testing in Underserved and Vulnerable Populations [NA]
Clinical trial with terminated status related to COVID-19 testing in underserved populations; results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-02-13Clinical Trial Update: Red Cell Half Life Determination in Patients With and Without Sickle Cell Disease [EARLY_Phase 1]
Early-phase 1 clinical trial evaluating red blood cell half-life in patients with and without sickle cell disease; study completed with resu…
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CLINICAL_TRIALS trial_result · 2024-02-09Clinical Trial Update: Therapeutic Anticoagulation Strategy for Acute Chest Syndrome [Phase 3]
A Phase 3 trial evaluating therapeutic anticoagulation strategy for Acute Chest Syndrome in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Long-term Safety and Efficacy of Ferriprox® in Iron Overloaded Patients With Sickle Cell Disease or Other Anemias [Phase 4]
Phase 4 trial assessing long-term safety and efficacy of Ferriprox in iron-overloaded patients, including those with sickle cell disease and…
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CLINICAL_TRIALS trial_result · 2024-01-10Clinical Trial Update: Non-Myeloablative Conditioning and Bone Marrow Transplantation [NA]
Clinical trial update involving non-myeloablative conditioning and bone marrow transplantation for sickle cell disease and related hemoglobi…
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CLINICAL_TRIALS trial_result · 2024-01-09Clinical Trial Update: Glutamine Role in Preventing Vaso-occlusive Crisis Among SCD Patients [Phase 4]
Phase 4 clinical trial assessing glutamine to prevent vaso-occlusive crises in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients [Phase 3]
Phase 3 study comparing two doses of crizanlizumab to placebo in adolescents and adults with sickle cell disease; results were posted in 202…
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CLINICAL_TRIALS trial_result · 2024-01-08Clinical Trial Update: Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients [Phase 3]
Phase 3 trial comparing two doses of crizanlizumab to placebo in adolescents and adults with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2023-12-26Clinical Trial Update: Intranasal Sufentanil for Analgesia of Severe Sickle Cell Vaso-occlusive Pain Crisis in the Pediatric [Phase 3]
Phase 3 clinical trial evaluating intranasal sufentanil for analgesia in pediatric severe sickle cell vaso-occlusive crisis; not yet recruit…
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CLINICAL_TRIALS trial_result · 2023-12-13Clinical Trial Update: iCanCope With Sickle Cell Pain [NA]
Clinical trial update for the iCanCope with Sickle Cell Pain study has completed; results posted in December 2023.
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CLINICAL_TRIALS trial_result · 2023-12-08Clinical Trial Update: Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome [Phase 2]
Phase 2 trial update on defibrotide for sickle cell disease–related acute chest syndrome has completed.
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CLINICAL_TRIALS trial_result · 2023-11-22Clinical Trial Update: Integration of mHEALTH Into the Care of Patients With Sickle Cell Disease to Increase Hydroxyurea Utilization [NA]
Clinical trial update on integrating mHealth into care to increase hydroxyurea utilization in sickle cell disease; study completed with resu…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Actigraphy Improvement With Voxelotor (ActIVe) Study [Phase 4]
Phase 4 trial update evaluating actigraphy improvements with voxelotor (ActIVe) in sickle cell disease patients has completed with results p…
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CLINICAL_TRIALS trial_result · 2023-11-21Clinical Trial Update: Dose Escalation Study to Evaluate the Safety, Tolerability, PK and PD of Voxelotor in Patients With SCD [Phase 2]
Phase 2 dose-escalation trial evaluating the safety, tolerability, pharmacokinetics and pharmacodynamics of voxelotor in patients with sickl…
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CLINICAL_TRIALS trial_result · 2023-11-01Clinical Trial Update: SMILES: Study of Montelukast in Sickle Cell Disease [Phase 2, Phase 3]
A clinical trial update for Montelukast in sickle cell disease progressing through Phase 2 and Phase 3.
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CLINICAL_TRIALS trial_result · 2023-10-18Clinical Trial Update: A Study of IMR-687 in Subjects With Sickle Cell Disease [Phase 2]
Phase 2 study of IMR-687 in sickle cell disease has been terminated and results have been posted.
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CLINICAL_TRIALS trial_result · 2023-10-12Clinical Trial Update: Transplantation for Patients With Sickle Cell Disease From Mismatched Family Donors of Bone Marrow [Phase 2]
Phase 2 clinical trial evaluating transplantation from mismatched family donors of bone marrow for patients with sickle cell disease has com…
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CLINICAL_TRIALS trial_result · 2023-09-26Clinical Trial Update: Long Term Follow-up Study for Patients Enrolled on the BP-004 Clinical Study [Phase 1, Phase 2]
Long-term follow-up update from BP-004 study (Phase 1/Phase 2) by Bellicum Pharmaceuticals; study status TERMINATED with results posted in 2…
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CLINICAL_TRIALS trial_result · 2023-09-21Clinical Trial Update: Hemolysis Related Complications in SCD. A Phase II Study With Voxelotor [Phase 2]
Phase II trial investigating voxelotor for sickle cell disease focusing on hemolysis-related complications; current status unknown.
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CLINICAL_TRIALS trial_result · 2023-09-15Clinical Trial Update: Conditioning Regimen for Allogeneic Hematopoietic Stem-Cell Transplantation [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating conditioning regimens for allogeneic hematopoietic stem-cell transplantation has completed recruitment…