Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Study to Learn About Sickle Cell Disease In Adult Patients
Pfizer-sponsored clinical trial in adults with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-07-12Clinical Trial Update: Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation (HaploHCT) Following Reduced Intensity Conditioning (RIC) for Selected High Risk Non-Malignant Diseases [Phase 2]
This Phase 2 clinical trial update reports the termination of a haploidentical hematopoietic stem cell transplantation study using reduced-i…
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CLINICAL_TRIALS trial_result · 2024-06-28Clinical Trial Update: Virtual Reality as an Adjuvant Therapy for Sickle Cell Vaso-Occlusive Crisis in the Pediatric Emergency Department [NA]
A completed clinical trial evaluating virtual reality as an adjuvant therapy for pediatric sickle cell vaso-occlusive crisis in the emergenc…
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CLINICAL_TRIALS trial_result · 2024-06-27Clinical Trial Update: Using Patient-Centered Guidelines in a Technology Platform to Improve Health Care in Adults With Sickle Cell Disease [NA]
A completed clinical trial evaluating a technology platform that applies patient-centered guidelines to improve health care for adults with …
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Hydroxyurea Adherence for Personal Best in Sickle Cell Disease (HABIT): Efficacy Trial [NA]
The HABIT trial evaluating adherence to hydroxyurea in sickle cell disease has completed, with results posted in 2024.
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CLINICAL_TRIALS trial_result · 2024-06-26Clinical Trial Update: Microvascular Blood Flow in Sickle Cell Anemia [NA]
A clinical trial evaluating microvascular blood flow in people with sickle cell disease/sickle cell anemia has completed and posted its resu…
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CLINICAL_TRIALS trial_result · 2024-06-24Clinical Trial Update: Prospective, Observational Study in Sickle Cell Disease Patients on Crizanlizumab Treatment in Middle East Countries and India
This document notes the termination of a prospective, observational study evaluating crizanlizumab in sickle cell disease patients in Middle…
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CLINICAL_TRIALS trial_result · 2024-06-21Clinical Trial Update: Validating Pain Scales in Children and Young Adults
National Cancer Institute completed a clinical trial focused on validating pain scales in children and young adults with sickle cell disease…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Abatacept for GVHD Prophylaxis After Hematopoietic Stem Cell Transplantation for Pediatric Sickle Cell Disease [Phase 1]
This Phase 1 clinical trial evaluated abatacept as prophylaxis against graft-versus-host disease after hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2024-06-13Clinical Trial Update: Stem Cell Transplant in Sickle Cell Disease and Thalassemia [Phase 2]
Phase 2 clinical trial update on hematopoietic stem cell transplantation for sickle cell disease and beta-thalassemia; the study is currentl…
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CLINICAL_TRIALS trial_result · 2024-06-12Clinical Trial Update: Mobile-Directly Observed Therapy on Adherence to Hydroxyurea [Phase 2]
Phase 2 trial evaluating mobile directly observed therapy to improve adherence to hydroxyurea in patients with sickle cell disease; the stud…
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CLINICAL_TRIALS trial_result · 2024-06-10Clinical Trial Update: A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD) [Phase 1]
Pfizer completed a Phase 1 study evaluating single-dose and multiple-dose regimens of GBT021601-012 in participants with Sickle Cell Disease…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Study Exploring the Effect of Crizanlizumab on Kidney Function in Patients With Chronic Kidney Disease Caused by Sickle Cell Disease [Phase 2]
A Phase 2 trial evaluating the effect of crizanlizumab on kidney function in patients with chronic kidney disease caused by sickle cell dise…
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CLINICAL_TRIALS trial_result · 2024-06-04Clinical Trial Update: Evaluation of Low-cost Techniques for Detecting Sickle Cell Disease and β-thalassemia in Nepal and Canada [NA]
A completed clinical trial evaluated low-cost testing methods for detecting sickle cell disease and beta-thalassemia in Nepal and Canada, wi…
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CLINICAL_TRIALS trial_result · 2024-05-17Clinical Trial Update: Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients
A completed clinical trial evaluating strategies to improve red blood cell transfusions for chronically transfused patients with sickle cell…
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CLINICAL_TRIALS trial_result · 2024-05-16Clinical Trial Update: "Association of Proteinuria and Progression of Kidney Dysfunction in Sickle Cell Disease"Disease
A completed clinical trial evaluating the relationship between proteinuria and progression of kidney dysfunction in sickle cell disease, foc…
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CLINICAL_TRIALS trial_result · 2024-05-10Clinical Trial Update: A Study Aimed to Assess the Needs of Subjects With Sickle Cell Disease and Healthcare Professionals Managing Sickle Cell Disease Patients in Selected Nigerian Centres
A completed clinical trial conducted in selected Nigerian centers to assess the needs of individuals with sickle cell disease and the health…
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CLINICAL_TRIALS trial_result · 2024-05-08Clinical Trial Update: Specifying Interventions From the Sickle Cell Disease Implementation Consortium (SCDIC)
This clinical trial update from the Sickle Cell Disease Implementation Consortium outlines the interventions specified for sickle cell disea…
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CLINICAL_TRIALS trial_result · 2024-05-07Clinical Trial Update: Desmopressin for Bedwetting in Children With SCD [Phase 4]
A Phase 4 trial evaluating desmopressin for bedwetting in children with sickle cell disease was terminated, with results posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-05-06Clinical Trial Update: Hydroxyurea Adherence for Personal Best in Sickle Cell Treatment: HABIT [NA]
The HABIT trial evaluating hydroxyurea adherence in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-05-02Clinical Trial Update: Voxelotor Neurocognitive Function Study [Phase 3]
Phase 3 trial evaluating voxelotor for neurocognitive function in sickle cell disease was terminated; results were posted in May 2024.
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CLINICAL_TRIALS trial_result · 2024-05-01Clinical Trial Update: PINPOINT: Gaming Technology for SCD Pain [NA]
A completed clinical trial evaluated PINPOINT gaming technology for pain management in sickle cell disease; results were posted on May 1, 20…
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CLINICAL_TRIALS trial_result · 2024-04-30Clinical Trial Update: Designing an Implementation Strategy for Delivering Routine Mental Health Screening and Treatment [NA]
A terminated clinical trial evaluated an implementation strategy for delivering routine mental health screening and treatment for patients w…
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CLINICAL_TRIALS trial_result · 2024-04-29Clinical Trial Update: Hematopoietic Stem Cell Transplant for Sickle Cell Disease [Phase 1]
Phase 1 trial update on hematopoietic stem cell transplantation for sickle cell disease, with the study status listed as completed.
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CLINICAL_TRIALS trial_result · 2024-04-23Clinical Trial Update: Pharmacokinetics and Pharmacodynamics Study of SEG101 (Crizanlizumab) in Sickle Cell Disease (SCD) Patients With Vaso- Occlusive Crisis (VOC) [Phase 2]
Phase 2 pharmacokinetics and pharmacodynamics study of crizanlizumab (SEG101) in sickle cell disease patients with vaso-occlusive crisis; th…