Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2024-12-11Clinical Trial Update: A Study of a Single Dose of Inclacumab to Reduce Re-admission in Participants With Sickle Cell Disease and Recurrent Vaso-occlusive Crises [Phase 3]
Pfizer's Phase 3 study evaluating a single dose of inclacumab to reduce hospital readmissions in sickle cell disease patients with recurrent…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Community Health Workers and mHealth for Sickle Cell Disease Care [NA]
A completed clinical trial evaluating the impact of community health workers and mobile health tools on care for patients with sickle cell d…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) for Patients With Severe Sickle Cell Disease [NA]
Terminated clinical trial evaluating haploidentical hematopoietic stem cell transplantation for severe sickle cell disease, with results pos…
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: Acupuncture for Pain in Sickle Cell Disease [NA]
A clinical trial evaluating acupuncture for pain in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2024-12-04Clinical Trial Update: AB1 in Adult Patients with Sickle Cell Disease (SCD) [Phase 1, Phase 2]
A Phase 1/2 study of AB1 in adults with Sickle Cell Disease has been terminated.
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CLINICAL_TRIALS trial_result · 2024-11-29Clinical Trial Update: Nonmyeloablative Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease and Beta-thalassemia in People With Higher Risk of Transplant Failure [Phase 2]
Phase 2 trial update examining a nonmyeloablative peripheral blood stem cell transplantation approach for sickle cell disease and beta-thala…
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CLINICAL_TRIALS trial_result · 2024-11-22Clinical Trial Update: Voxelotor CYP and Transporter Cocktail Interaction Study [Phase 1]
Pfizer completed a Phase 1 pharmacokinetic interaction study of voxelotor with CYP and transporter substrates; results have been posted.
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CLINICAL_TRIALS trial_result · 2024-11-19Clinical Trial Update: Age of Blood in Sickle Cell Transfusion [Phase 2, Phase 3]
Results from a Phase 2/Phase 3 trial evaluating the impact of the age of transfused red blood cells on outcomes in sickle cell disease have …
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CLINICAL_TRIALS trial_result · 2024-11-18Clinical Trial Update: Intranasal Ketamine for Pain Control in Patients with Sickle Cell Disease and Vaso-occlusive Episode (VOE) in the PED [Phase 3]
A Phase 3 trial evaluating intranasal ketamine for pain control during vaso-occlusive episodes in children with sickle cell disease was term…
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CLINICAL_TRIALS trial_result · 2024-11-05Clinical Trial Update: Investigation Into the Use of BAH243 Lentiviral Vector for Gene Therapy in Treating Sickle Cell Disease [Phase 1, Phase 2]
A clinical trial update indicates that BAH243, a lentiviral vector gene therapy, is being investigated for sickle cell disease in Phase 1/Ph…
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CLINICAL_TRIALS trial_result · 2024-10-30Clinical Trial Update: Cerebrovascular Reserve and White Matter Disease in Patients with Chronic Anemia
Completed clinical trial assessing cerebrovascular reserve and white matter disease in patients with chronic anemia due to thalassemia or si…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: Pharmacokinetics of Oral Hydroxyurea Solution [Phase 1, Phase 2]
Completed Phase 1/2 pharmacokinetics study of an oral hydroxyurea solution in sickle cell disease and related hemoglobin disorders, with res…
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CLINICAL_TRIALS trial_result · 2024-10-28Clinical Trial Update: HRV-B for Symptom Management in Sickle Cell Patients [NA]
Clinical trial update indicates completion of a study evaluating HRV-B for symptom management in sickle cell disease. The snippet does not r…
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CLINICAL_TRIALS trial_result · 2024-10-08Clinical Trial Update: A Study Evaluating the Safety and Efficacy of Lovo-cel in Severe Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating the safety and efficacy of Lovo-cel in severe sickle cell disease has completed, with results posted o…
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CLINICAL_TRIALS trial_result · 2024-10-01Clinical Trial Update: HEMAGO Monitoring and Impact on the Occurrence of Complications During Pregnancy in Sickle Cell Patients
A completed clinical trial evaluating the HEMAGO monitoring system and its effect on pregnancy-related complications in women with Sickle Ce…
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CLINICAL_TRIALS trial_result · 2024-09-24Clinical Trial Update: Bone Marrow Transplantation vs Standard of Care in Patients With Severe Sickle Cell Disease (BMT CTN 1503) [Phase 2]
This Phase 2 trial (BMT CTN 1503) compares bone marrow transplantation versus standard of care in patients with severe sickle cell disease, …
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CLINICAL_TRIALS trial_result · 2024-09-20Clinical Trial Update: A Trial for Prevention of Recurrent Ischemic Priapism in Men With Sickle Cell Disease: A Pilot Study [Phase 2]
A Phase 2 pilot trial, sponsored by Vanderbilt University Medical Center, evaluated prevention of recurrent ischemic priapism in men with si…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: Pharmacokinetics and Pharmacodynamics of Rifaximin Novel Formulations in Patients With Sickle Cell Disease [Phase 2]
Phase 2 trial assessing the pharmacokinetics and pharmacodynamics of rifaximin novel formulations in sickle cell disease has completed, with…
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CLINICAL_TRIALS trial_result · 2024-09-19Clinical Trial Update: L-citrulline Injection in Patients Aged 6-21 Years Old with Sickle Cell Disease Presenting with Vaso-Occlusive Crisis (VOC) [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating intravenous L-citrulline in youths with sickle cell disease presenting with vaso-occlusive crisis was …
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CLINICAL_TRIALS trial_result · 2024-09-03Clinical Trial Update: LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) [NA]
The Sickle Cell Trevor Thompson Transition Project (ST3P-UP) has completed and posted results. The trial was sponsored by Wake Forest Univer…
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CLINICAL_TRIALS trial_result · 2024-08-16Clinical Trial Update: SMYLS: A Self-management Program for Youth Living With Sickle Cell Disease [NA]
SMYLS is a self-management program for youths living with sickle cell disease. The trial has completed and posted its results on 2024-08-16.
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CLINICAL_TRIALS trial_result · 2024-08-09Clinical Trial Update: Vitamin D for Sickle-cell Respiratory Complications [Phase 2]
Phase 2 trial evaluating Vitamin D supplementation for respiratory complications in sickle cell disease has completed and results were poste…
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CLINICAL_TRIALS trial_result · 2024-08-07Clinical Trial Update: Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease [Phase 1, Phase 2]
Describes a Phase 1/2 nonmyeloablative haploidentical peripheral blood stem cell transplantation approach for sickle cell disease. The trial…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: Nitrous Oxide Analgesia Vaso-occlusive Crisis [Phase 2]
Phase 2 trial evaluating nitrous oxide analgesia for vaso-occlusive crisis in sickle cell disease has completed, with results posted on 2024…
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CLINICAL_TRIALS trial_result · 2024-07-16Clinical Trial Update: A Low-Interventional Study of an Electronic Sickle Cell Disease Patient Reported Outcomes in Sickle Cell Participants
A low-interventional study evaluating electronic patient-reported outcomes in sickle cell disease participants has been terminated.