Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Heart Disease in Sickle Cell Anemia
The clinical trial examining heart disease in patients with sickle cell disease, including pulmonary hypertension, has completed.
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CLINICAL_TRIALS trial_result · 2017-06-08Clinical Trial Update: Propanolol and Red Cell Adhesion Non-asthmatic Children Sickle Cell Disease [Phase 1]
A Phase 1 trial evaluating propranolol and red blood cell adhesion in non-asthmatic children with sickle cell disease was terminated.
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Ledipasvir/Sofosbuvir Fixed-Dose Combination for 12 or 24 Weeks in Genotype 1 or 4 HCV Infected Adults With Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating fixed-dose Ledipasvir/Sofosbuvir for 12 or 24 weeks in adults with Hepatitis C infection and sickle cell disease; r…
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CLINICAL_TRIALS trial_result · 2017-05-25Clinical Trial Update: Use of Mobile Technology for Intensive Training in Medication Management [NA]
This clinical trial update notes a completed Duke University study evaluating the use of mobile technology to provide intensive training in …
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CLINICAL_TRIALS trial_result · 2017-05-11Clinical Trial Update: Evaluation of Non-invasive Endothelial Function in Children Sickle by Vascular Ultrasound [NA]
A completed clinical trial evaluating non-invasive measures of endothelial function in children with sickle cell disease using vascular ultr…
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CLINICAL_TRIALS trial_result · 2017-05-09Clinical Trial Update: Stem Cell Transplant for Hemoglobinopathy [Phase 2, Phase 3]
Phase 2/3 trial update on stem cell transplant for hemoglobinopathy shows completed status with results posted.
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CLINICAL_TRIALS trial_result · 2017-05-03Clinical Trial Update: A Brief Laboratory-Based Hypnosis Session for Pain in Sickle Cell Disease [NA]
A completed UCLA-sponsored clinical trial evaluating a brief laboratory-based hypnosis session for pain in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Haploidentical Stem Cell Transplant for Patients With Sickle Cell Disease and Prior Stroke or Abnormal Transcranial Ultrasound [Phase 1]
A Phase 1 trial evaluating haploidentical stem cell transplantation in patients with sickle cell disease who have had prior stroke or abnorm…
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CLINICAL_TRIALS trial_result · 2017-04-26Clinical Trial Update: Use of Hydroxyurea and Magnesium Pidolate for Treatment of Sickle Cell Disease [Phase 1]
Phase 1 clinical trial evaluating hydroxyurea in combination with magnesium pidolate for sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2017-04-19Clinical Trial Update: Quality of Care of Children With Sickle Cell Disease (SCD) Screened at Birth in France
This completed clinical trial update describes the quality of care for children with sickle cell disease who were screened at birth in Franc…
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CLINICAL_TRIALS trial_result · 2017-04-13Clinical Trial Update: Sildenafil for Treatment of Priapism in Men With Sickle Cell Anemia [Phase 2]
Phase 2 clinical trial evaluating sildenafil for treatment of priapism in men with sickle cell disease has completed and results are posted.
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: Drug Interaction Study of GBT440 With Caffeine, S-warfarin, Omeprazole, and Midazolam in Healthy Subjects [Phase 1]
Phase 1 study assessing potential drug interactions between GBT440 (voxelotor) and caffeine, S-warfarin, omeprazole, and midazolam in health…
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: A Study of the Absorption, Metabolism, and Excretion of GBT440 in Healthy Male Subjects [Phase 1]
Phase 1 trial evaluating the absorption, metabolism, and excretion of GBT440 (voxelotor) in healthy male subjects has completed. The update …
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CLINICAL_TRIALS trial_result · 2017-04-12Clinical Trial Update: A Single-Dose Relative Bioavailability Study Of GBT440 300 mg Capsules in Healthy Subjects [Phase 1]
Phase 1 study of voxelotor (GBT440) 300 mg capsules in healthy subjects to assess single-dose relative bioavailability.
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CLINICAL_TRIALS trial_result · 2017-04-11Clinical Trial Update: Transcranial Doppler (TCD) With Transfusions Changing to Hydroxyurea [Phase 3]
A Phase 3 trial investigating a shift from transfusions to hydroxyurea in sickle cell anemia was terminated, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-03-28Clinical Trial Update: Molecular Phenotyping of Asthma in Sickle Cell Disease
A completed clinical trial investigating molecular phenotyping of asthma in individuals with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2017-03-24Clinical Trial Update: Evaluation of Different Dose Regimens of Aes-103 Given for 28 Days to Subjects With Stable Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating different dose regimens of Aes-103 over 28 days in subjects with stable sickle cell disease; study terminated with …
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CLINICAL_TRIALS trial_result · 2017-03-01Clinical Trial Update: Decitabine for High-Risk Sickle Cell Disease [Phase 2]
This update reports results from a Phase 2 clinical trial of decitabine for high-risk sickle cell disease, with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-02-28Clinical Trial Update: SANGUINATE™ in Sickle Cell Disease Associated Leg Ulcer [Phase 2]
Phase 2 study of SANGUINATE for leg ulcers in sickle cell disease has completed, reporting results from the trial.
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CLINICAL_TRIALS trial_result · 2017-02-17Clinical Trial Update: Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial [Phase 1]
Phase 1 feasibility trial evaluating inhaled corticosteroids to prevent recurrence of acute chest syndrome in children aged 1-4 with sickle …
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Examining Cognitive Function and Brain Abnormalities in Adults With Sickle Cell Disease - Pilot Intervention Study [Phase 1]
Clinical trial update on a Phase 1 pilot intervention study examining cognitive function and brain abnormalities in adults with sickle cell …
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CLINICAL_TRIALS trial_result · 2017-02-15Clinical Trial Update: Decompression Coring Versus Conservative Therapy in Patients With Avascular Necrosis of the Hip Related to Sickle Cell Disease [NA]
This update reports completion of a trial comparing decompression coring surgery to conservative treatment for avascular necrosis of the hip…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Clinical Importance of Treating Iron Overload in Sickle Cell Disease [Phase 3]
This is a Phase 3 trial update about the clinical importance of treating iron overload in sickle cell disease. The study status is TERMINATE…
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CLINICAL_TRIALS trial_result · 2017-02-08Clinical Trial Update: Safety and Efficacy of Sodium Nitrite in Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating sodium nitrite for safety and efficacy in sickle cell disease was terminated; results were posted in 2…
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CLINICAL_TRIALS trial_result · 2017-02-01Clinical Trial Update: Web-MAP Intervention for Youth With Sickle Cell Disease [NA]
Completed clinical trial evaluating a Web-MAP intervention for youths with Sickle Cell Disease.