Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2018-06-15Clinical Trial Update: Patient-Provider Tools to Improve the Transition to Adult Care in Sickle Cell Disease [NA]
This clinical trial update reports results from a completed study evaluating patient-provider tools to improve the transition from pediatric…
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CLINICAL_TRIALS trial_result · 2018-06-01Clinical Trial Update: Fertility Preservation in Women Who Will Have Gonadotoxic Therapy or Hematopoetic Stem Cell Transplantation, and in Women With Sickle Cell Disease
A NICHD-sponsored clinical trial on fertility preservation for women undergoing gonadotoxic therapy or hematopoietic stem cell transplantati…
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CLINICAL_TRIALS trial_result · 2018-05-30Clinical Trial Update: Prevalence of Problematic Use of Equimolar Mixture of Oxygen and Nitrous Oxide and Analgesics in the Sickle-cell Disease
This update summarizes results from a completed study assessing the prevalence of problematic use of an equimolar mixture of oxygen and nitr…
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: A Study of SANGUINATE for the Treatment of Vaso-occlusive Crisis (VOC) in Adult Sickle Cell Disease Patients [Phase 2]
A Phase 2 trial evaluating SANGUINATE for treatment of vaso-occlusive crisis in adults with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2018-05-23Clinical Trial Update: Study of SANGUINATE™ In the Treatment of Sickle Cell Disease Patients With Vaso-Occlusive Crisis [Phase 2]
This ClinicalTrials.gov entry reports the completion of a Phase 2 study evaluating SANGUINATE for treatment of vaso-occlusive crisis in sick…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: A Self-Management Intervention for Youth With Sickle Cell Disease and Their Families: Phase I
Phase I trial evaluating a self-management intervention for youth with sickle cell disease and their families has completed.
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: A Pharmacokinetic (PK) and Pharmacodynamic (PD) Dose-ranging Phase II Study of Ticagrelor in Paediatric Patients With Sickle Cell Disease [Phase 2]
Phase II pharmacokinetic/pharmacodynamic dose-ranging study of ticagrelor in pediatric patients with sickle cell disease completed with resu…
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CLINICAL_TRIALS trial_result · 2018-05-11Clinical Trial Update: Ketamine Infusion for Acute Sickle Cell Crisis in the Emergency Department [NA]
A clinical trial investigating ketamine infusion for acute pain in sickle cell crisis in the emergency department has been terminated.
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CLINICAL_TRIALS trial_result · 2018-02-07Clinical Trial Update: A Phase II Trial of Regadenoson in Sickle Cell Anemia [Phase 2]
Phase II trial update for regadenoson in sickle cell anemia has completed with results posted.
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CLINICAL_TRIALS trial_result · 2017-12-26Clinical Trial Update: Evaluating the Safety and Effectiveness of Bone Marrow Transplants in Children With Sickle Cell Disease (BMT CTN 0601) [Phase 2]
Phase 2 trial evaluating bone marrow transplants in children with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: A Study to Assess the Effect of Ticagrelor in Reducing the Number of Days With Pain in Patients With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial evaluating ticagrelor to reduce pain days in sickle cell disease has completed with results posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-12-14Clinical Trial Update: Safety, Tolerability, Pharmacokinetics, And Pharmacodynamics Study Of PF-04447943, Co-Administered With And Without Hydroxyurea, In Subjects With Stable Sickle Cell Disease [Phase 1]
Phase 1 trial update on PF-04447943 with/without hydroxyurea in stable sickle cell disease examining safety, tolerability, PK, and PD.
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CLINICAL_TRIALS trial_result · 2017-12-11Clinical Trial Update: Epidemiology and Pathophysiological Mechanisms of HTAP in SS and SC Children in Martinique and Guadeloupe. [NA]
This update reports on a completed clinical trial in children with sickle cell disease in Martinique and Guadeloupe, investigating the epide…
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CLINICAL_TRIALS trial_result · 2017-10-27Clinical Trial Update: Microvessels and Heart Problems in Sickle Cell Disease
NHLBI-sponsored clinical trial investigating microvessel and heart problems in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2017-10-17Clinical Trial Update: Point-of-Delivery Prenatal Test Results Through mHealth to Improve Birth Outcome [NA]
An update on trial results evaluating a point-of-delivery prenatal test delivered via mobile health to improve birth outcomes.
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CLINICAL_TRIALS trial_result · 2017-09-29Clinical Trial Update: Bone Marrow Transplantation in Young Adults With Severe Sickle Cell Disease [Phase 2]
Phase 2 clinical trial evaluating bone marrow transplantation in young adults with severe sickle cell disease. The study is completed and re…
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CLINICAL_TRIALS trial_result · 2017-08-22Clinical Trial Update: Safety of ICL670 vs. Deferoxamine in Sickle Cell Disease Patients With Iron Overload Due to Blood Transfusions [Phase 2]
A completed Phase 2 safety study comparing ICL670 with deferoxamine in sickle cell disease patients with transfusional iron overload.
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CLINICAL_TRIALS trial_result · 2017-08-10Clinical Trial Update: A Phase III Safety and Efficacy Study of L-Glutamine to Treat Sickle Cell Disease or Sickle βo-thalassemia [Phase 3]
Phase III trial evaluating safety and efficacy of L-Glutamine for sickle cell disease and sickle β0-thalassemia has completed with results p…
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CLINICAL_TRIALS trial_result · 2017-08-07Clinical Trial Update: Clinical Trial to Study the Safety and Tolerability of Memantin Mepha® in Sickle Cell Disease Patients [Phase 2]
A Phase 2 trial evaluating the safety and tolerability of Memantin Mepha in adults with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2017-08-04Clinical Trial Update: Comparing Acute Pain Management Protocols for Patients With Sickle Cell Disease [Phase 4]
Phase 4 clinical trial update comparing acute pain management protocols for patients with sickle cell disease; results were posted in 2017.
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CLINICAL_TRIALS trial_result · 2017-08-02Clinical Trial Update: A Study to Compare if the Uptake of Ticagrelor in the Body Differs When Different Tablets Are Administered [Phase 1]
A Phase 1 pharmacokinetic study from AstraZeneca compared Ticagrelor absorption using different tablet formulations in individuals with sick…
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CLINICAL_TRIALS trial_result · 2017-08-01Clinical Trial Update: Evaluating Thromboelastography (TEG) and ETP in Sickle Adults
This clinical trial update notes the completion of a study evaluating thromboelastography (TEG) and endogenous thrombin potential (ETP) in a…
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CLINICAL_TRIALS trial_result · 2017-07-25Clinical Trial Update: Sickle Cell Disease Conditioning for Bone Marrow Transplant [Phase 1]
Phase 1 trial evaluating conditioning regimens for bone marrow transplantation in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2017-07-17Clinical Trial Update: Losartan for Sickle Cell Kidney Disease [EARLY_Phase 1]
This update reports the completion of an early-phase (Phase 1) trial evaluating losartan for sickle cell kidney disease.
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CLINICAL_TRIALS trial_result · 2017-07-02Clinical Trial Update: Nitric Oxide and Sickle Cell Pain
A National Institute of Nursing Research study evaluating inhaled nitric oxide for sickle cell pain has been terminated.