Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2020-07-07Clinical Trial Update: Steroid Treatment for Sickle Cell Pain Crisis [Phase 3]
Phase 3 trial evaluating steroid treatment for pain crisis in sickle cell disease; study terminated, results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-05-13Clinical Trial Update: Study of GMI-1070 for the Treatment of Sickle Cell Pain Crisis [Phase 2]
Phase 2 trial update for GMI-1070 in sickle cell pain crisis (vaso-occlusive crisis) has completed.
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CLINICAL_TRIALS trial_result · 2020-04-20Clinical Trial Update: Peripheral Blood Stem Cell Collection for Sickle Cell Disease (SCD) Patients [Phase 1]
Phase 1 clinical trial updating peripheral blood stem cell collection in sickle cell disease patients; study completed with results posted i…
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CLINICAL_TRIALS trial_result · 2020-04-16Clinical Trial Update: Self-Management for Youth and Families Living With SCD - SMYLS [NA]
Clinical trial update on a self-management program for youth and families living with sickle cell disease; study completed with results post…
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CLINICAL_TRIALS trial_result · 2020-04-13Clinical Trial Update: The Effect of Rivaroxaban in Sickle Cell Disease [Phase 2]
Phase 2 clinical trial assessing rivaroxaban in sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-03-23Clinical Trial Update: Vitamin D Supplementation in Children With Sickle Cell Disease [Phase 3]
Phase 3 trial evaluating vitamin D supplementation in children with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2020-03-19Clinical Trial Update: European Sickle Cell Disease Cohort - Hydroxyurea
A completed European cohort study evaluating hydroxyurea for sickle cell disease with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-03-11Clinical Trial Update: Apixaban in Patients With Sickle Cell Disease [Phase 3]
Phase 3 trial update for apixaban in sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2020-03-10Clinical Trial Update: A Study Evaluating the Safety and Efficacy of LentiGlobin BB305 Drug Product in β-Thalassemia Major (Also Referred to as Transfusion-dependent β-Thalassemia [TDT]) and Sickle Cell Disease [Phase 1, Phase 2]
A completed early-phase study evaluating the safety and efficacy of LentiGlobin BB305 in transfusion-dependent beta-thalassemia and sickle c…
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CLINICAL_TRIALS trial_result · 2020-02-20Clinical Trial Update: Optimizing Hydroxyurea Therapy in Children With SCA In Malaria Endemic Areas [Phase 3]
Phase 3 trial updating hydroxyurea therapy in children with sickle cell disease in malaria-endemic areas has completed.
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CLINICAL_TRIALS trial_result · 2020-01-31Clinical Trial Update: Study to Assess Safety and Impact of SelG1 With or Without Hydroxyurea Therapy in Sickle Cell Disease Patients With Pain Crises [Phase 2]
Phase 2 clinical trial evaluating safety and impact of SelG1 with or without hydroxyurea in sickle cell disease patients experiencing pain c…
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CLINICAL_TRIALS trial_result · 2020-01-22Clinical Trial Update: Methadone in Pediatric and Adult Sickle Cell Patients [NA]
A completed clinical trial evaluating methadone in pediatric and adult patients with sickle cell disease; results posted in 2020.
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CLINICAL_TRIALS trial_result · 2019-12-16Clinical Trial Update: Hydroxyurea for the Treatment of Patients With Sickle Cell Anemia [Phase 2]
Phase 2 clinical trial update for hydroxyurea in sickle cell anemia.
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CLINICAL_TRIALS trial_result · 2019-11-01Clinical Trial Update: A Phase - IIa - IIb, Trial to Study the Safety, Tolerability and Efficacy of Memantine as a Long-term Treatment of SCD [Phase 2]
Phase 2 trial examining memantine as a long-term treatment for sickle cell disease to assess safety, tolerability, and efficacy.
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CLINICAL_TRIALS trial_result · 2019-10-14Clinical Trial Update: Haploidentical PBMC Transplant for Severe Congenital Anemias [Phase 1, Phase 2]
This clinical trial update concerns haploidentical peripheral blood mononuclear cell transplant for sickle cell anemia, conducted in Phase 1…
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CLINICAL_TRIALS trial_result · 2019-09-23Clinical Trial Update: Comparison of Allogeneic Matched Related Haematopoietic Stem Cell Transplantation After a Reduced Intensity Conditioning Regimen With Standard of Care in Adolescents and Adults With Severe Sickle Cell Disease [Phase 3]
A Phase 3 clinical trial comparing allogeneic matched related hematopoietic stem cell transplantation after reduced-intensity conditioning v…
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CLINICAL_TRIALS trial_result · 2019-09-13Clinical Trial Update: Music Therapy in Sickle Cell Transition Study [NA]
A completed clinical trial studying music therapy in sickle cell disease has results posted.
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CLINICAL_TRIALS trial_result · 2019-08-28Clinical Trial Update: SCD-Haplo: Phase II Study of HLA-Haploidentical SCT for Aggressive SCD [Phase 2]
Phase II study of HLA-haploidentical stem cell transplantation for aggressive sickle cell disease was terminated; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-08-06Clinical Trial Update: Assessment of Algorithm-Based Hydroxyurea Dosing on Fetal Hemoglobin Response, Acute Complications, and Organ Function in People With Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial assessed algorithm-based hydroxyurea dosing for sickle cell disease, focusing on fetal hemoglobin response, acute…
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CLINICAL_TRIALS trial_result · 2019-08-02Clinical Trial Update: TAPS2 Transfusion Antenatally in Pregnant Women With SCD [Phase 2]
Phase 2 clinical trial update evaluating antenatal transfusion in pregnant women with sickle cell disease (SCD).
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD [Phase 2]
Phase 2 clinical trial update for sevuparin infusion in managing acute vaso-occlusive crises in sickle cell disease has been completed.
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CLINICAL_TRIALS trial_result · 2019-07-16Clinical Trial Update: Feasibility Study of Unfractionated Heparin in Acute Chest Syndrome [Phase 2]
A Phase 2 feasibility trial of unfractionated heparin for acute chest syndrome in sickle cell disease was terminated, with results posted.
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CLINICAL_TRIALS trial_result · 2019-07-15Clinical Trial Update: Music Therapy in Sickle Cell Pain Mixed Methods Study [NA]
A completed mixed-methods study evaluating music therapy for pain management in sickle cell disease; results posted in 2019.
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CLINICAL_TRIALS trial_result · 2019-06-26Clinical Trial Update: Allogeneic SCT of CordIn™, in Patients With Hemoglobinopathies [Phase 1, Phase 2]
Phase 1/2 clinical trial update for Allogeneic cord blood stem cell therapy CordIn in sickle cell disease and thalassemia; study status term…
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CLINICAL_TRIALS trial_result · 2019-06-17Clinical Trial Update: Comparison of Patient Centered Outcomes for People With Sickle Cell Disease in the Acute Care Setting
A completed clinical trial evaluating patient-centered outcomes for individuals with sickle cell disease in acute care settings; results pos…