Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2021-03-17Clinical Trial Update: Improving Self-Management in Adolescents With Sickle Cell Disease [NA]
A completed clinical trial focusing on improving self-management in adolescents with sickle cell disease; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-03-01Clinical Trial Update: Role of Virtual Reality (VR) in Patients With Sickle Cell Disease (SCD) [NA]
Clinical trial update on the role of virtual reality in patients with sickle cell disease; study has terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-02-10Clinical Trial Update: Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease [Phase 3]
Phase 3 trial of rivipansel (GMI-1070) in hospitalized sickle cell vaso-occlusive crises was terminated.
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CLINICAL_TRIALS trial_result · 2021-02-02Clinical Trial Update: L-Glutamine Therapy for Sickle Cell Anemia [Phase 2]
Phase 2 clinical trial of L-Glutamine therapy for sickle cell anemia has been terminated; results posted in 2021.
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CLINICAL_TRIALS trial_result · 2021-01-29Clinical Trial Update: L-Glutamine Therapy for Sickle Cell Anemia and Sickle ß0 Thalassemia [Phase 2]
Phase 2 clinical trial of L-Glutamine therapy for sickle cell anemia and sickle beta-zero thalassemia completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-28Clinical Trial Update: A Phase 2 Study of the Effects of 6R-BH4 in Subjects With Sickle Cell Disease [Phase 2]
Phase 2 trial update on 6R-BH4 for sickle cell disease; study completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-01-27Clinical Trial Update: Different Treatment Modalities in the Management of the Painful Crisis in Pediatric Sickle- Cell Anemia [Phase 2, Phase 3]
Phase 2/3 clinical trial evaluating different treatment modalities for managing painful crisis in pediatric sickle cell disease has complete…
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CLINICAL_TRIALS trial_result · 2021-01-07Clinical Trial Update: Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) [Phase 3]
Phase 3 clinical trial update for voxelotor in sickle cell disease has completed with posted results.
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CLINICAL_TRIALS trial_result · 2020-12-17Clinical Trial Update: Study of Efficacy, Safety and Tolerability of ACZ885 (Canakinumab) in Pediatric and Young Adult Patients With Sickle Cell Anemia [Phase 2]
Phase 2 clinical trial evaluating the efficacy, safety and tolerability of canakinumab (ACZ885) in pediatric and young adult patients with s…
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CLINICAL_TRIALS trial_result · 2020-12-08Clinical Trial Update: Macitentan in Pulmonary Hypertension of Sickle Cell Disease [Phase 2]
Phase 2 trial of macitentan for pulmonary hypertension associated with sickle cell disease was terminated; results have been posted.
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CLINICAL_TRIALS trial_result · 2020-11-09Clinical Trial Update: Realizing Effectiveness Across Continents With Hydroxyurea (REACH) [Phase 1, Phase 2]
This clinical trial update covers hydroxyurea in Phase 1/2 for sickle cell disease, with results posted on 2020-11-09.
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CLINICAL_TRIALS trial_result · 2020-11-06Clinical Trial Update: Contraception in Women With Sickle Cell Disease [Phase 4]
A Phase 4 clinical trial investigating contraception in women with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2020-11-05Clinical Trial Update: HSCT For Patients With High Risk Hemoglobinopathies Using Reduced Intensity [Phase 1, Phase 2]
A phase 1/2 clinical trial evaluating reduced intensity conditioning and hematopoietic stem cell transplantation for high-risk hemoglobinopa…
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CLINICAL_TRIALS trial_result · 2020-10-19Clinical Trial Update: Omega-3 Fatty Acids in Sickle Cell Disease [Phase 1, Phase 2]
A clinical trial update on omega-3 fatty acids in sickle cell disease has been terminated with results posted.
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CLINICAL_TRIALS trial_result · 2020-10-14Clinical Trial Update: Phase I/II Pilot Study of Mixed Chimerism to Treat Hemoglobinopathies [Phase 1, Phase 2]
Phase I/II pilot study investigating mixed chimerism as a treatment approach for sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2020-10-08Clinical Trial Update: Ketorolac Versus Ibuprofen to Treat Painful Episodes of Sickle Cell Disease [Phase 4]
Phase 4 trial comparing ketorolac to ibuprofen for painful episodes in sickle cell disease was terminated with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-10-01Clinical Trial Update: Assessing the Safety of Buprenorphine in People With Sickle Cell Disease [Phase 2]
Phase 2 trial assessing the safety of buprenorphine in people with sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-09-29Clinical Trial Update: Losartan to Reverse Sickle Nephropathy [Phase 2]
A Phase 2 trial evaluating losartan for reversing sickle cell nephropathy has completed enrollment with results posted in 2020.
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CLINICAL_TRIALS trial_result · 2020-09-10Clinical Trial Update: Niacin to Improve Blood Flow in People With Sickle Cell Disease [Phase 2]
Phase 2 clinical trial update investigating niacin to improve血 flow in people with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Pediatric Hydroxyurea Phase III Clinical Trial (BABY HUG) Follow-up Observational Study II Protocol
Follow-up observational protocol for pediatric hydroxyurea (BABY HUG) Phase III trial in sickle cell anemia; study completed with results po…
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CLINICAL_TRIALS trial_result · 2020-08-20Clinical Trial Update: Long-Term Effects of Hydroxyurea in Children With Sickle Cell Anemia (The BABY HUG Follow-up Study)
Follow-up study reporting long-term effects of hydroxyurea in children with sickle cell anemia (BABY HUG follow-up).
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CLINICAL_TRIALS trial_result · 2020-08-19Clinical Trial Update: Hydroxyurea to Prevent Organ Damage in Children With Sickle Cell Anemia [Phase 3]
Phase 3 trial investigating hydroxyurea for prevention of organ damage in children with sickle cell anemia; trial completed with posted resu…
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CLINICAL_TRIALS trial_result · 2020-08-18Clinical Trial Update: Vaporized Cannabis for Chronic Pain Associated With Sickle Cell Disease [Phase 1, Phase 2]
Clinical trial update on vaporized cannabis for pain in sickle cell disease (Phase 1/2) completed with results posted.
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CLINICAL_TRIALS trial_result · 2020-08-03Clinical Trial Update: Primary Prevention of Stroke in Children With SCD in Sub-Saharan Africa II [Phase 3]
Phase 3 trial updating primary prevention of stroke in children with sickle cell disease in Sub-Saharan Africa has completed.
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CLINICAL_TRIALS trial_result · 2020-07-31Clinical Trial Update: Bone Marrow Transplantation, Hemoglobinopathies, SCALLOP [NA]
Clinical trial update for a bone marrow transplantation study in sickle cell disease and hemoglobin SC, terminated with results posted in 20…