Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2022-06-15Clinical Trial Update: Voxelotor Sickle Cell Exercise Study [Phase 4]
Phase 4 trial update for voxelotor in sickle cell anemia has completed.
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CLINICAL_TRIALS trial_result · 2022-06-06Clinical Trial Update: Arginine Therapy for Sickle Cell Disease Pain [Phase 2]
A Phase 2 clinical trial evaluating arginine therapy for pain in sickle cell disease has completed with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-06-02Clinical Trial Update: Outcomes Mandate National Integration With Cannabis as Medicine [Phase 2]
Phase 2 clinical trial update focusing on integrating cannabis as medicine for various chronic pain conditions, with status currently UNKNOW…
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CLINICAL_TRIALS trial_result · 2022-05-09Clinical Trial Update: Preventing Sickle Cell Kidney Disease [Phase 2]
Phase 2 clinical trial update on preventing sickle cell kidney disease; status terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-04-27Clinical Trial Update: Allogeneic SCT of NiCord®, UCB-Derived Ex Vivo Expanded Stem and Progenitor Cells, in Patients With Hemoglobinopathies [Phase 1, Phase 2]
Phase 1/2 trial investigating NiCord allogeneic stem and progenitor cells for hemoglobinopathies (sickle cell disease and thalassemia).
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CLINICAL_TRIALS trial_result · 2022-04-14Clinical Trial Update: A Study of IMR-687 in Adult Participants With Sickle Cell Anemia (Homozygous HbSS or Sickle-β0 Thalassemia) [Phase 2]
Phase 2 trial of IMR-687 in adults with sickle cell disease (HbSS or Sickle-β0 thalassemia) has completed and results were posted on 2022-04…
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CLINICAL_TRIALS trial_result · 2022-04-12Clinical Trial Update: Acupuncture for Adults With Sickle Cell Disease (SCD): A Feasibility Study [NA]
A feasibility study on acupuncture for adults with sickle cell disease was terminated; results were posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-03-18Clinical Trial Update: Hydroxyurea Therapy: Optimizing Access in Pediatric Populations Everywhere [Phase 2]
Phase 2 trial update on hydroxyurea therapy aimed at optimizing access in pediatric patients; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2022-03-04Clinical Trial Update: An Extension Study of IMR-687 in Adult Patients With Sickle Cell Anemia [Phase 2]
An extension study of IMR-687 in adults with sickle cell anemia (Phase 2) is ongoing.
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CLINICAL_TRIALS trial_result · 2022-01-19Clinical Trial Update: Moderate Dose Hydroxyurea for Secondary Stroke Prevention in Children With Sickle Cell Disease in Sub-Saharan Africa [Phase 3]
Phase 3 trial evaluating moderate-dose hydroxyurea for secondary stroke prevention in children with sickle cell disease in Sub-Saharan Afric…
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CLINICAL_TRIALS trial_result · 2021-12-23Clinical Trial Update: Low Dose Ketamine and Acute Pain Crisis [Phase 4]
Phase 4 clinical trial update evaluating low-dose ketamine for acute pain crisis in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2021-10-29Clinical Trial Update: Hypnosis to Manage Pain and Symptoms in Patients With Sickle Cell Disease [Phase 3]
Phase 3 trial exploring hypnosis as a non-pharmacologic approach to manage pain and symptoms in sickle cell disease patients has completed.
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CLINICAL_TRIALS trial_result · 2021-10-22Clinical Trial Update: Hydoxycarbamide and L-Carnitine Therapy in Sickle Cell Anemia [Phase 4]
Phase 4 clinical trial investigating hydroxycarbamide and L-Carnitine therapy in sickle cell disease has been completed.
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CLINICAL_TRIALS trial_result · 2021-10-21Clinical Trial Update: Hydroxyurea and Transfusion [Phase 2]
Phase 2 clinical trial evaluating hydroxyurea and transfusion for sickle cell disease has been completed.
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CLINICAL_TRIALS trial_result · 2021-09-24Clinical Trial Update: Cardiovascular Complications of Sickle Cell Disease
Clinical trial update on cardiovascular complications in sickle cell disease with completed status and results posted.
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CLINICAL_TRIALS trial_result · 2021-08-27Clinical Trial Update: Evaluation of the Impact of Renal Function on the Pharmacokinetics of SIKLOS ® (DARH) [Phase 4]
Phase 4 study evaluating how renal function affects the pharmacokinetics of SIKLOS (DARH) in sickle cell disease; completed with posted resu…
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CLINICAL_TRIALS trial_result · 2021-08-10Clinical Trial Update: Efficacy and Safety of Ferriprox® in Patients With Sickle Cell Disease or Other Anemias [Phase 4]
Phase 4 clinical trial update on ferriprox for iron overload and sickle cell disease/other anemias; study terminated with results posted.
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CLINICAL_TRIALS trial_result · 2021-08-03Clinical Trial Update: Antioxidant Therapy to Reduce Inflammation in Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating antioxidant therapy to reduce inflammation in sickle cell disease has completed with results posted.
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CLINICAL_TRIALS trial_result · 2021-07-16Clinical Trial Update: Acceptability, Feasibility and Safety of a Yoga Program for Chronic Pain in Sickle Cell Disease [NA]
A terminated clinical trial evaluating acceptability, feasibility, and safety of a yoga program for chronic pain in sickle cell disease; res…
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CLINICAL_TRIALS trial_result · 2021-06-25Clinical Trial Update: Hydroxyurea Management in Kids: Intensive Versus Stable Dosage Strategies [Phase 2]
Phase 2 trial comparing intensive versus stable hydroxyurea dosing strategies in children with sickle cell anemia; results posted.
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CLINICAL_TRIALS trial_result · 2021-06-16Clinical Trial Update: A Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (V114-023/PNEU-SICKLE) [Phase 3]
Phase 3 trial evaluating safety, tolerability, and immunogenicity of V116 in children with sickle cell disease has completed; results posted…
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CLINICAL_TRIALS trial_result · 2021-06-10Clinical Trial Update: Glutamine Therapy for Hemolysis-Associated Pulmonary Hypertension [Phase 2]
Phase 2 clinical trial evaluating glutamine therapy for hemolysis-associated pulmonary hypertension in patients with sickle cell disease. St…
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CLINICAL_TRIALS trial_result · 2021-04-20Clinical Trial Update: Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis [Phase 2]
Phase 2 clinical trial evaluating adjuvant low-dose ketamine for pediatric sickle cell vaso-occlusive crisis has completed with results post…
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CLINICAL_TRIALS trial_result · 2021-04-09Clinical Trial Update: Effect of Ticagrelor vs. Placebo in the Reduction of Vaso-occlusive Crises in Pediatric Patients With Sickle Cell Disease [Phase 3]
Phase 3 trial assessing ticagrelor vs placebo for reducing vaso-occlusive crises in pediatric sickle cell disease; study terminated with pos…
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CLINICAL_TRIALS trial_result · 2021-04-02Clinical Trial Update: Does IV Acetaminophen Reduce Opioid Requirement in Pediatric Patients With Acute Sickle Cell Crises? [Phase 4]
Phase 4 trial assessing whether IV acetaminophen reduces opioid requirements in pediatric patients during acute sickle cell crises; study co…