Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2023-08-29Clinical Trial Update: Lidocaine Intravenous in the Emergency Department For Sickle Cell Crisis [Phase 2]
Phase 2 trial investigating intravenous lidocaine for emergency department management of sickle cell crisis.
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CLINICAL_TRIALS trial_result · 2023-08-14Clinical Trial Update: Measurement of Cerebral Blood Flow Using Transcranial Doppler Ultrasound in Children With Sickle Cell Disease [NA]
A completed clinical trial evaluating transcranial Doppler ultrasound to measure cerebral blood flow in children with sickle cell disease; r…
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CLINICAL_TRIALS trial_result · 2023-07-21Clinical Trial Update: A Study of the Effect of IW-1701 (Olinciguat), a Stimulator of Soluble Guanylate Cyclase (sGC), on Patients With Sickle Cell Disease (SCD) [Phase 2]
Phase 2 trial investigating olinciguat (IW-1701), a soluble guanylate cyclase stimulator, in sickle cell disease has completed with results …
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CLINICAL_TRIALS trial_result · 2023-07-19Clinical Trial Update: A Multi-Center Study of Riociguat in Patients With Sickle Cell Diseases [Phase 2]
Phase 2 multicenter trial evaluating riociguat in patients with sickle cell disease has been completed with results posted.
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CLINICAL_TRIALS trial_result · 2023-07-03Clinical Trial Update: Comparing Individualized vs. Weight Based Protocols to Treat Vaso-Occlusive Episodes in Sickle Cell Disease [Phase 3]
A Phase 3 trial comparing individualized versus weight-based treatment protocols for vaso-occlusive episodes in sickle cell disease was term…
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CLINICAL_TRIALS trial_result · 2023-06-27Clinical Trial Update: Fixed Dose Flavonoid Isoquercetin on Thrombo-Inflammatory Biomarkers in Subjects With Stable Sickle Cell Disease [Phase 2]
A Phase 2 clinical trial evaluating fixed-dose flavonoid isoquercetin on thrombo-inflammatory biomarkers in adults with stable sickle cell d…
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CLINICAL_TRIALS trial_result · 2023-06-18Clinical Trial Update: Inhaled Mometasone to Promote Reduction in Vasoocclusive Events 2 [Phase 2]
Phase 2 trial evaluating inhaled mometasone for reducing vaso-occlusive events in sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2023-05-10Clinical Trial Update: RElated Haplo-DonoR Haematopoietic stEm Cell Transplantation for Adults With Severe Sickle Cell Disease [Phase 3]
Phase 3 clinical trial update for related haploidentical hematopoietic stem cell transplantation in adults with severe sickle cell disease, …
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CLINICAL_TRIALS trial_result · 2023-05-08Clinical Trial Update: Clonidine With Morphine in Patient Controlled Analgesia Pump in Vaso-Occlusive Crisis in Sickle Cell Disease Patient [Phase 4]
A Phase 4 clinical trial evaluating clonidine added to morphine in a patient-controlled analgesia pump for vaso-occlusive crises in sickle c…
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CLINICAL_TRIALS trial_result · 2023-05-03Clinical Trial Update: Endothelial Monocyte-activating Polypeptide-II in Egyptian Sickle Patients [Phase 4]
Phase 4 clinical trial update for Endothelial Monocyte-activating Polypeptide-II in Egyptian patients with Sickle Cell Disease.
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CLINICAL_TRIALS trial_result · 2023-04-12Clinical Trial Update: Study of Vitamin D in Children With Sickle Cell Disease [Phase 1, Phase 2]
Phase 1/2 clinical trial evaluating vitamin D in children with sickle cell disease completed; results posted in 2023.
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CLINICAL_TRIALS trial_result · 2023-03-23Clinical Trial Update: Transfusion Alternatives Pre-operatively in Sickle Cell Disease (TAPS) [Phase 3]
Phase 3 clinical trial update for Transfusion Alternatives Pre-operatively in Sickle Cell Disease (TAPS) has been terminated.
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CLINICAL_TRIALS trial_result · 2023-03-09Clinical Trial Update: Risk Clinical Stratification of Sickle Cell Disease in Nigeria, Assessment of Efficacy/Safety of Hydroxyurea Treatment [Phase 4]
Phase 4 trial assessing risk stratification and the efficacy/safety of hydroxyurea treatment in sickle cell disease in Nigeria.
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CLINICAL_TRIALS trial_result · 2023-03-07Clinical Trial Update: Evaluation of the Efficacy of Intra-nasal Sufentanil for Analgesia of Vaso-occlusive Crisis in Sickle-cell Adults. [Phase 3]
Phase 3 clinical trial evaluating intra-nasal sufentanil for analgesia in adults with vaso-occlusive crisis due to sickle cell disease.
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CLINICAL_TRIALS trial_result · 2023-02-13Clinical Trial Update: Low Dose Iron Chelation as TReatment of Oxidative Damage in Sickle Cell Disease [Phase 2]
Phase 2 trial update evaluating low dose iron chelation to treat oxidative damage in sickle cell disease completed.
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CLINICAL_TRIALS trial_result · 2023-02-03Clinical Trial Update: Evaluation of the Lung Capillary Blood Volume in Children With Sickle Cell Disease [Phase 3]
Phase 3 trial evaluating lung capillary blood volume in children with sickle cell disease has completed.
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CLINICAL_TRIALS trial_result · 2022-12-28Clinical Trial Update: Hydroxyurea to Prevent Brain Injury in Sickle Cell Disease [Phase 2]
Phase 2 trial evaluating hydroxyurea to prevent brain injury in sickle cell disease; study completed with results posted in December 2022.
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CLINICAL_TRIALS trial_result · 2022-11-23Clinical Trial Update: Acceptability of a New Paediatric Formulation of Hydroxycarbamide in Children With Sickle Cell Disease. [Phase 2]
Phase 2 trial update evaluating acceptability of a new paediatric formulation of hydroxycarbamide in children with sickle cell disease.
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CLINICAL_TRIALS trial_result · 2022-11-07Clinical Trial Update: Stem Cell Transplantation for Sickle Cell Anemia [Phase 3]
Phase 3 trial updates on stem cell transplantation for sickle cell disease have been completed with results posted.
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CLINICAL_TRIALS trial_result · 2022-11-02Clinical Trial Update: Hyperbaric-oxygen Therapy (HBOT) Versus Placebo for Treating Vaso-Occlusive Crisis (VOC) in Sickle Cell Disease (SCD) [Phase 3]
A Phase 3 clinical trial evaluating hyperbaric oxygen therapy versus placebo for vaso-occlusive crisis in sickle cell disease; current statu…
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CLINICAL_TRIALS trial_result · 2022-09-09Clinical Trial Update: Immunogenicity Study of an Anti-pneumococcal Vaccination Strategy in Patients With Sickle Cells Disease [Phase 2]
Phase 2 immunogenicity study evaluating an anti-pneumococcal vaccination strategy in patients with sickle cell disease; completed.
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CLINICAL_TRIALS trial_result · 2022-08-09Clinical Trial Update: High Dose Vitamin D for Sickle Cell Disease [Phase 2]
Phase 2 trial updating results for high-dose vitamin D in sickle cell disease.
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CLINICAL_TRIALS trial_result · 2022-08-02Clinical Trial Update: Pharmacokinetics and Safety of Endari (L-glutamine) in Sickle Cell Disease Patients [Phase 4]
Phase 4 trial updating pharmacokinetics and safety of Endari (L-glutamine) in sickle cell disease patients completed.
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CLINICAL_TRIALS trial_result · 2022-07-29Clinical Trial Update: Evaluation of the AMICUS RBCx System in Sickle Cell Patients [NA]
Completed clinical trial evaluating the AMICUS RBCx System in sickle cell anemia with results posted in 2022.
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CLINICAL_TRIALS trial_result · 2022-07-12Clinical Trial Update: A Dose-Finding Study of AG-348 in Sickle Cell Disease [EARLY_Phase 1]
Early-phase dose-finding trial of AG-348 in sickle cell disease completed; results posted in 2022.