Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-01-14Clinical Trial Update: Virtual Reality As Adjunct Therapy for Vaso-Occlusive Pain [NA]
Ongoing clinical trial evaluating virtual reality as adjunct therapy for vaso-occlusive pain in sickle cell disease, currently recruiting.
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Feasibility and Efficacy of Attentional-Control Training in Sickle Cell Disease [NA]
A clinical trial update shows a feasibility and efficacy study of attentional-control training in sickle cell disease is currently recruitin…
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CLINICAL_TRIALS research · 2025-01-10Clinical Trial Update: Evaluation of the Impact of Red Blood Cell Exchange on Thrombo-inflammation in Sickle Cell Disease
This clinical trial evaluates whether red blood cell exchange can reduce thrombo-inflammation in sickle cell disease; recruitment has not ye…
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CLINICAL_TRIALS research · 2025-01-07Clinical Trial Update: Optimizing Hydroxyurea Dosage With Pharmakokinetic in Patients Suffering of Moderate to Severe Sickle Cell Anemia [Phase 2, Phase 3]
A Phase 2/3 trial is evaluating pharmacokinetic-guided dosing of hydroxyurea in patients with moderate to severe sickle cell disease.
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Pulmonary Functions in Sickle Cell Disease: Response to Acu-TENS [NA]
Acu-TENS is being studied in a clinical trial to evaluate pulmonary function in individuals with sickle cell disease; the study is currently…
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CLINICAL_TRIALS research · 2025-01-01Clinical Trial Update: Pilot Study on the Value of Bedside Pleuropulmonary Ultrasound in Patients With Sickle Cell Disease Presenting With Vaso-occlusive Crisis
A pilot study is evaluating the value of bedside pleuropulmonary ultrasound in patients with sickle cell disease presenting with a vaso-occl…
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CLINICAL_TRIALS research · 2024-12-24Clinical Trial Update: The Longitudinal Relationship of HU Adherence to HRQOL, Barriers to Adherence and Habit in SCD. [NA]
Clinical trial update documenting an ongoing study on how adherence to hydroxyurea relates to health-related quality of life and barriers in…
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: A Study Evaluating Gene Therapy With BB305 Lentiviral Vector in Sickle Cell Disease [Phase 3]
A Phase 3 clinical trial evaluating BB305 Lentiviral Vector gene therapy for sickle cell disease is currently active but not recruiting.
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CLINICAL_TRIALS research · 2024-12-10Clinical Trial Update: Nonmyeloablative Stem Cell Transplant in Children with Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor [Phase 2]
A Phase 2 nonmyeloablative stem cell transplant trial in children with sickle cell disease using a major ABO-incompatible matched sibling do…
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CLINICAL_TRIALS research · 2024-12-06Clinical Trial Update: Minocycline in Neurocognitive Outcomes - Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial from the University of Cincinnati is investigating whether minocycline can improve neurocognitive outcomes in sickl…
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CLINICAL_TRIALS research · 2024-11-27Clinical Trial Update: SCRIPT: Sickle Cell Risk in Pregnancy Tool
SCRIPT is a study evaluating a sickle cell risk in pregnancy tool. Enrollment is by invitation.
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CLINICAL_TRIALS research · 2024-11-25Clinical Trial Update: Early Human Leukocyte Antigen (HLA) Matched Sibling Hematopoietic Stem Cell Transplantation [Phase 2]
A Phase 2 clinical trial update evaluating early HLA-matched sibling hematopoietic stem cell transplantation for sickle cell disease. The tr…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: Expanded Access Protocol for Adults and Pediatric Patients With Sickle Cell Disease Who Have No Alternative Treatment Options
Pfizer's Expanded Access Protocol for adults and pediatric patients with sickle cell disease who have no alternative treatment options is no…
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CLINICAL_TRIALS research · 2024-11-20Clinical Trial Update: An mHealth Strategy to Improve Medication Adherence in Adolescents With Sickle Cell Disease [NA]
This clinical trial update reports an mHealth strategy intended to improve medication adherence in adolescents with sickle cell disease; the…
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CLINICAL_TRIALS research · 2024-11-15Clinical Trial Update: The Role of Red Cell Characteristics, Angiogenesis, Viscosity and Oxygenation in the Pathophysiology of Sickle Cell Related Retinopathy
Completed clinical trial investigating how red blood cell characteristics, angiogenesis, viscosity, and oxygenation relate to the pathophysi…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Real World Patient Characteristics and Treatment Patterns From Crizanlizumab Use: Preliminary Analysis From Select Sickle Cell Centers
This document reports a preliminary real-world analysis of patient characteristics and treatment patterns among crizanlizumab users in selec…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Characteristics and Treatment Patterns of Patients With Sickle Cell Disease in Globin Research Network for Data and Discovery Registry
This completed registry study describes the characteristics and treatment patterns of patients with sickle cell disease in the Globin Resear…
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CLINICAL_TRIALS research · 2024-10-29Clinical Trial Update: Decision-Making and Quality of Life Surrounding Hematologic Disease and Gene Therapy
A clinical trial update discusses decision-making and quality-of-life considerations for hematologic diseases undergoing gene therapy, with …
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CLINICAL_TRIALS research · 2024-10-04Clinical Trial Update: The Relationship of Platelet Counts With Sickle Cell Anemia in the Eastern Region of Saudi Arabia
This clinical trial update describes a study assessing the relationship between platelet counts and sickle cell disease in the Eastern Regio…
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CLINICAL_TRIALS research · 2024-09-26Clinical Trial Update: Screening of Coexistence Between Sickle Cell Anaemia and G6PD Deficiency
Clinical trial update indicates a screening study to assess coexistence between sickle cell disease and glucose-6-phosphate dehydrogenase de…
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CLINICAL_TRIALS research · 2024-08-30Clinical Trial Update: Ketorolac for Acute Vaso-Occlusive Crisis in Pediatric Sickle Cell Disease [Phase 4]
Phase 4 clinical trial evaluating ketorolac for acute vaso-occlusive crisis in pediatric sickle cell disease; status is not yet recruiting.
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CLINICAL_TRIALS research · 2024-08-27Clinical Trial Update: ESCORT-HU Extension: European Sickle Cell Disease Cohort - Hydroxyurea - Extension Study
Extension study update for the European sickle cell disease cohort evaluating hydroxyurea (ESCORT-HU Extension); current status is active bu…
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CLINICAL_TRIALS research · 2024-08-23Clinical Trial Update: Testing the Sickle Cell Caregiver Collaboration for Child Development (SCCCD) Intervention [NA]
Clinical trial update for the Sickle Cell Caregiver Collaboration for Child Development (SCCCD) intervention assessing caregiver collaborati…
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CLINICAL_TRIALS research · 2024-08-22Clinical Trial Update: Development and Evaluation of an Information Management System and Communication System for Population-wide Point-of-care Infant Sickle Cell Disease Screening [NA]
A clinical trial update describing the development and evaluation of an information management and communication system for population-wide …
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CLINICAL_TRIALS research · 2024-07-31Clinical Trial Update: Clinical Study of BRL-101 in Severe SCD [NA]
Clinical trial update indicating that BRL-101 is enrolling by invitation for severe sickle cell disease.