Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Effect of EMDR for Reduction of Pain Interference in Children With Sickle Cell Disease [NA]
A clinical trial is recruiting to evaluate whether Eye Movement Desensitization and Reprocessing (EMDR) therapy reduces pain interference in…
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CLINICAL_TRIALS research · 2025-05-29Clinical Trial Update: A Study of Intravenous L-Citrulline in Patients Aged 6-21 Years Old With Sickle Cell Disease Presenting to Emergency Departments in Acute Vaso-Occlusive Crisis [Phase 3]
This update describes a Phase 3 clinical trial evaluating intravenous L-Citrulline in patients aged 6-21 with sickle cell disease presenting…
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CLINICAL_TRIALS research · 2025-05-25Clinical Trial Update: A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease [Phase 1]
This clinical trial update describes a Phase 1 study of nicotinamide with oral tetrahydrouridine and decitabine for high-risk sickle cell di…
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CLINICAL_TRIALS research · 2025-05-07Clinical Trial Update: PET Imaging of Vaso-Occlusive Crisis (VOC) in SCD [Phase 1]
A Phase 1 clinical trial is evaluating PET imaging to study vaso-occlusive crisis in sickle cell disease. The study is currently recruiting.
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CLINICAL_TRIALS research · 2025-05-04Clinical Trial Update: RH Genotype Matched RBC Transfusions [Phase 1, Phase 2]
This clinical trial update describes a Phase 1/Phase 2 study evaluating RH genotype-matched red blood cell transfusions in patients with sic…
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CLINICAL_TRIALS research · 2025-04-18Clinical Trial Update: A Gene Transfer Study Inducing Fetal Hemoglobin in Sickle Cell Disease (GRASP, BMT CTN 2001) [Phase 2]
This clinical trial update reports on a Phase 2 gene transfer study aimed at inducing fetal hemoglobin for sickle cell disease (GRASP, BMT C…
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CLINICAL_TRIALS research · 2025-04-11Clinical Trial Update: Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD) [Phase 1, Phase 2]
This document updates a Phase 1/2 clinical trial of allogeneic stem cell transplantation for aggressive sickle cell disease; the trial is cu…
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CLINICAL_TRIALS research · 2025-04-09Clinical Trial Update: Promoting Utilization and Safety of Hydroxyurea Using Precision in Africa [Phase 3]
A Phase 3 clinical trial update describing the use of hydroxyurea with precision medicine approaches to improve utilization and safety for s…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Applying Directly Observed Therapy to Hydroxyurea to Realize Effectiveness [NA]
This clinical trial update describes a study evaluating directly observed therapy for hydroxyurea to improve its effectiveness in sickle cel…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: A Long-Term Follow-Up Study of Participants With Sickle Cell Disease or Transfusion Dependent β-Thalassemia Who Received EDIT-301
A long-term follow-up study is ongoing to monitor participants with sickle cell disease or transfusion-dependent beta-thalassemia who receiv…
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CLINICAL_TRIALS research · 2025-04-02Clinical Trial Update: Pilot Study "AHSP as a Biomarker of Sickle Cell Disease in a Population of Adults and Children" [NA]
Pilot study evaluating AHSP as a biomarker for sickle cell disease in adults and children is currently recruiting. The trial is sponsored by…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Pressure Pain Tolerance in Relation to Balance and Strength in Children [NA]
A clinical trial studying pressure pain tolerance in relation to balance and strength in children with Sickle Cell Anemia; recruitment is on…
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CLINICAL_TRIALS research · 2025-03-21Clinical Trial Update: Glucose Metabolism in Sickle Cell Disease
ClinicalTrials.gov update notes the status of a study evaluating glucose metabolism in sickle cell disease, including the conditions Sickle …
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Phenotypic and Transcriptomic Description of Megakaryocytes in Sickle Cell Patient
This clinical trial update describes the phenotypic and transcriptomic characteristics of megakaryocytes in patients with sickle cell diseas…
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CLINICAL_TRIALS research · 2025-03-20Clinical Trial Update: Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department [Phase 3]
Phase 3 trial evaluating analgesia with parecoxib versus morphine in emergency department patients with sickle cell disease experiencing a c…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Synthetic Generation of Hematological Data Over Federated Computing Frameworks: SCD Use Case
A clinical trial update describing a study on synthetic generation of hematologic data across federated computing frameworks, using Sickle C…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease.
A completed clinical trial update examining links between cognitive function and clinical, biological, and neuroradiological outcomes in adu…
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CLINICAL_TRIALS research · 2025-03-04Clinical Trial Update: A Socio-ecological Approach for Improving Self-management in Adolescents With SCD [Phase 2]
Phase 2 clinical trial update on a socio-ecological intervention to improve self-management in adolescents with sickle cell disease; current…
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CLINICAL_TRIALS research · 2025-02-18Clinical Trial Update: ERN-EuroBloodNet Registry on Patients With Rare Red Blood Cell Defects and COVID-19
This clinical trials registry update reports completion of the ERN-EuroBloodNet registry documenting patients with rare red blood cell defec…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Optimizing the Management of Sickle Cell Patients on Hydroxyurea: The Value of Therapeutic Pharmacological Monitoring [NA]
A clinical trial investigating therapeutic pharmacological monitoring to optimize hydroxyurea treatment for sickle cell disease.
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Advancing Feasibility and Acceptability of Digital Cognitive Rehabilitation in Sickle Cell Disease [NA]
The update indicates ongoing recruitment for a study assessing feasibility and acceptability of digital cognitive rehabilitation in sickle c…
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CLINICAL_TRIALS research · 2025-02-12Clinical Trial Update: Long-term Endurance Training in Sickle Cell Disease Patients: Impact on Clinical Profile, Physical Fitness, and Quality of Life. [NA]
Clinical trial evaluating long-term endurance training in patients with sickle cell disease to assess impact on clinical profile, physical f…
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CLINICAL_TRIALS research · 2025-02-11Clinical Trial Update: mAnaging siCkle CELl disEase Through incReased AdopTion of hydroxyurEa in Nigeria [NA]
A clinical trial update indicates ongoing recruitment in Nigeria for a study evaluating increased adoption of hydroxyurea to manage sickle c…
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CLINICAL_TRIALS research · 2025-01-24Clinical Trial Update: Sickle-cell Disease Registry of the GPOH
Registry-style clinical trial entry for Sickle cell disease under the GPOH, currently recruiting.
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CLINICAL_TRIALS research · 2025-01-15Clinical Trial Update: Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood Coagulation
This clinical trial investigates how biological phenotype relates to clinical severity in sickle cell disease and its impact on blood coagul…