Sickle Cell Disease
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CLINICAL_TRIALS research · 2025-08-21Clinical Trial Update: Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
This entry provides an update on a recruiting clinical trial evaluating the SCD BioChip, a biofluid chip technology for sickle cell disease.
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CLINICAL_TRIALS research · 2025-08-19Clinical Trial Update: Adapting the FACETS Program to Sickle Cell Disease [NA]
A clinical trial is adapting the FACETS program for sickle cell disease to address fatigue and related symptoms. The study is currently recr…
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: The BENeFiTS Trial in Beta Thalassemia Intermedia [Phase 1, Phase 2]
The BENeFiTS trial is a Phase 1/2 study in beta-thalassemia intermedia and sickle cell disease that is currently enrolling by invitation, sp…
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CLINICAL_TRIALS research · 2025-08-14Clinical Trial Update: CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation [Phase 1, Phase 2]
This document provides an update on a phase 1/2 clinical trial evaluating CD34+ stem cell selection for patients receiving allogeneic stem c…
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CLINICAL_TRIALS research · 2025-08-12Clinical Trial Update: T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias [Phase 1, Phase 2]
This clinical trials update notes that a T-cell depleted alternative donor bone marrow transplant for sickle cell disease and other anemias …
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion [Phase 2]
A Phase 2 clinical trial evaluating allogeneic stem cell transplantation with alpha/beta T cell and CD19+ B cell depletion for malignant and…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Haplo T-Cell Depleted Transplantation in High-Risk Sickle Cell Disease [Phase 2]
Clinical trial update for a Phase 2 study of haploidentical, T-cell depleted transplantation in high-risk sickle cell disease; the trial is …
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CLINICAL_TRIALS research · 2025-08-05Clinical Trial Update: Effects of the Contraceptive Implant in Women With Sickle Cell Disease [Phase 4]
Phase 4 clinical trial to assess the effects of the etonogestrel contraceptive implant in women with sickle cell disease. The study is curre…
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: A Stress and Pain Self-management m-Health App for Adult Outpatients With Sickle Cell Disease [NA]
A clinical trial update indicates a stress and pain self-management mobile health app for adult outpatients with sickle cell disease is curr…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: High-flow Oxygen for Vaso-occlusive Pain Crisis [NA]
A clinical trial is evaluating high-flow oxygen for vaso-occlusive pain crisis in sickle cell disease. The study is currently recruiting in …
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Bone Loss, Physical Function and Frailty in Older Women With Sickle Cell Trait Sickle Cell Trait
This clinical trial is studying bone loss, physical function, and frailty in older women with sickle cell trait, sponsored by UConn Health, …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Therapeutic Response Evaluation and Adherence Trial (TREAT) [NA]
Therapeutic Response Evaluation and Adherence Trial (TREAT) is currently active but not recruiting. The associated condition is sickle cell …
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CLINICAL_TRIALS research · 2025-07-17Clinical Trial Update: Hydroxyurea Exposure Limiting Pregnancy and Follow-Up Lactation
This clinical trial is evaluating hydroxyurea exposure during pregnancy and lactation in people with sickle cell disease, currently recruiti…
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CLINICAL_TRIALS research · 2025-07-11Clinical Trial Update: Arginine Therapy for the Treatment of Pain in Children With Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial enrolling to assess arginine therapy for pain in children with sickle cell disease.
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CLINICAL_TRIALS research · 2025-07-08Clinical Trial Update: Exploratory Study on Global Reflexology in Sickle Cell Disease [NA]
An exploratory clinical trial examining global reflexology as a treatment for Sickle Cell Disease, with status RECRUITING.
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CLINICAL_TRIALS research · 2025-06-25Clinical Trial Update: Cannabidiol in Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/2 clinical trial evaluating cannabidiol for sickle cell disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-06-22Clinical Trial Update: Recruitment and Engagement in Care to Impact Practice Enhancement (RECIPE) for Sickle Cell Disease
The RECIPE trial for sickle cell disease, sponsored by RTI International, is actively recruiting to evaluate recruitment and engagement in c…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Comparing the Effectiveness of Matched Related Donor Hematopoietic Stem Cell Transplantation to Disease Modifying Therapy in Pediatric Patients With Sickle Cell Disease
This clinical trial is evaluating whether matched related donor hematopoietic stem cell transplantation provides better outcomes than diseas…
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CLINICAL_TRIALS research · 2025-06-19Clinical Trial Update: Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia [NA]
This entry reports a study evaluating the effect of MitoQ on platelet function and reactive oxygen species generation in patients with sickl…
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CLINICAL_TRIALS research · 2025-06-13Clinical Trial Update: Uganda Sickle Surveillance Study (US-3)
Uganda Sickle Surveillance Study (US-3) is a Uganda-based clinical trial recruiting participants to study sickle cell disease surveillance, …
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CLINICAL_TRIALS research · 2025-06-11Clinical Trial Update: 131I-apamistamab-based Conditioning for Hematopoietic Stem Cell Transplant (HSCT) in Advanced Sickle Cell Disease (SCD) [Phase 1]
A Phase 1 trial is evaluating 131I-apamistamab-based conditioning for hematopoietic stem cell transplantation in patients with advanced sick…
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Neonatal Screening for Haemoglobinopathies EmoCamp
This ClinicalTrials.gov entry reports a neonatal screening study for haemoglobinopathies (sickle cell disease) called EmoCamp, which is not …
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CLINICAL_TRIALS research · 2025-06-08Clinical Trial Update: Red Blood Cell Survival in Sickle Cell Disease [Phase 1]
Phase 1 clinical trial investigating red blood cell survival in sickle cell disease has completed.
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Impact of Regional Anesthesia on Inflammatory Mechanisms During Vaso-occlusive Crisis in Sickle Cell Patients
A clinical trial update indicates the study is currently recruiting to assess whether regional anesthesia can influence inflammatory pathway…
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CLINICAL_TRIALS research · 2025-06-03Clinical Trial Update: Molecular and Cellular Basis of Severe Forms of Dengue in Sickle Cell Patients
A clinical trial investigating the molecular and cellular basis of severe dengue in patients with sickle cell disease, currently recruiting.