Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-01-15Clinical Trial Update: CHOICES3: Sickle Cell Disease Parenting CHOICES [NA]
Clinical trial update for CHOICES3 (Sickle Cell Disease Parenting CHOICES) sponsored by the University of Florida; the study involves sickle…
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CLINICAL_TRIALS research · 2026-01-14Clinical Trial Update: Study to Understand the Genetic Risk of Developing an Immune Response After Blood Transfusions Among Individuals With Sickle Cell Disease
This recruiting study from the National Human Genome Research Institute aims to understand whether genetic factors influence the risk of dev…
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CLINICAL_TRIALS research · 2026-01-12Clinical Trial Update: ATHN Transcends: A Natural History Study of Non-Neoplastic Hematologic Disorders
Clinical trial update for ATHN Transcends, a natural history study of non-neoplastic hematologic disorders, currently recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Gene Transfer for Sickle Cell Disease [Phase 1]
Phase 1 clinical trial update for a gene transfer therapy targeting sickle cell disease; trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2026-01-09Clinical Trial Update: Study of Panobinostat (LBH589) in Patients With Sickle Cell Disease [Phase 1]
A Phase 1 clinical trial evaluating panobinostat (LBH589) in patients with sickle cell disease is currently recruiting.
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CLINICAL_TRIALS research · 2026-01-08Clinical Trial Update: A Safety, Efficacy, and Pharmacokinetic (PK) Study of HBI-002, an Oral Carbon Monoxide (CO) Therapeutic, in Subjects With Sickle Cell Disease (SCD) [Phase 1, Phase 2]
This document reports on an ongoing Phase 1/2 trial evaluating HBI-002, an oral carbon monoxide–releasing therapeutic, for sickle cell disea…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Peer Support for Adolescents and Emerging Adults With Sickle Cell Pain [NA]
A University of Pittsburgh-sponsored clinical trial is recruiting adolescents and emerging adults with sickle cell disease-related pain to a…
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Hypoxic Red Blood Cells in Sickle Cell Anemia [NA]
A clinical trial update on hypoxic red blood cells for sickle cell disease sponsored by Hemanext; the study status is NOT_YET_RECRUITING.
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CLINICAL_TRIALS research · 2026-01-07Clinical Trial Update: Reduced Intensity Conditioning and Familial HLA-Mismatched BMT for Non-Malignant Disorders [Phase 1, Phase 2]
A Phase 1/2 clinical trial at Washington University evaluates reduced-intensity conditioning and familial HLA-mismatched bone marrow transpl…
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CLINICAL_TRIALS research · 2026-01-05Clinical Trial Update: TMLI and Alemtuzumab for Treatment of Sickle Cell Disease [Phase 1]
Phase 1 trial evaluating total marrow irradiation with alemtuzumab conditioning for sickle cell disease, sponsored by City of Hope Medical C…
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CLINICAL_TRIALS research · 2025-12-26Clinical Trial Update: Lidocaine for Opioid Sparing in Vaso-occlusive Crisis of Sickle Cell Disease [Phase 3]
A Phase 3 clinical trial evaluating lidocaine as an opioid-sparing treatment for vaso-occlusive crises in sickle cell disease; the study is …
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CLINICAL_TRIALS research · 2025-12-24Clinical Trial Update: Virtual Reality Devices as an Adjunct to Usual Care for Patients With Sickle Cell Disease Experiencing Vaso-Occlusive Crises [NA]
A clinical trials registry entry reports ongoing recruitment for a study evaluating virtual reality devices as an adjunct to standard care f…
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CLINICAL_TRIALS research · 2025-12-19Clinical Trial Update: Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease [NA]
A completed clinical trial presenting functional and mechanistic insights into limb ulcers in patients with sickle cell disease.
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CLINICAL_TRIALS research · 2025-12-16Clinical Trial Update: BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease [Phase 1, Phase 2]
BEACON is a Phase 1/2 study evaluating BEAM-101 for severe sickle cell disease; the trial is currently active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-15Clinical Trial Update: Efficacy and Safety of SIL-8301 for Control of Hemolysis in a Uniform Sickle Cell Disease Endotype [Phase 2]
A Phase 2 clinical trial evaluating SIL-8301 for control of hemolysis in a uniform sickle cell disease endotype is not yet recruiting.
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CLINICAL_TRIALS research · 2025-12-12Clinical Trial Update: A Pilot Study on Neuroimaging in SCD: Part of The Boston Consortium to Cure Sickle Cell Disease
This entry describes a pilot neuroimaging study in sickle cell disease as part of The Boston Consortium to Cure Sickle Cell Disease. The tri…
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CLINICAL_TRIALS research · 2025-12-11Clinical Trial Update: The Influence of micro-and Macro Vascular Dysfunction on Clinical Severity in Adults With Sickle Cell Anemia (SS) and Sickle Cell Hemoglobin C Disease (SC) [NA]
This completed clinical trial update examines how micro- and macrovascular dysfunction influences clinical severity in adults with sickle ce…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Study of Vitamin B12 Metabolism in Children With Sickle Cell Disease Exposed to MEOPA
This clinical trial is recruiting to study Vitamin B12 metabolism in children with sickle cell disease who are exposed to MEOPA (nitrous oxi…
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CLINICAL_TRIALS research · 2025-12-10Clinical Trial Update: Promoting Resilience Among Adolescents and Young Adults With Sickle Cell Disease [NA]
A ClinicalTrials.gov update for a Boston Children's Hospital-sponsored study evaluating resilience-promoting interventions in adolescents an…
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CLINICAL_TRIALS research · 2025-12-09Clinical Trial Update: Prevention of Malnutrition in Children With Sickle Cell Disease [NA]
Clinical trial update indicating a study on preventing malnutrition in children with sickle cell disease is active but not recruiting.
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CLINICAL_TRIALS research · 2025-12-08Clinical Trial Update: SMYLS Multi-site Trial [NA]
The SMYLS multi-site trial for sickle cell disease is currently recruiting.
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CLINICAL_TRIALS research · 2025-12-04Clinical Trial Update: Sickle Cell Clinical Research and Intervention Program
A clinical trial update for the Sickle Cell Clinical Research and Intervention Program sponsored by St. Jude Children's Research Hospital, c…
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CLINICAL_TRIALS research · 2025-12-02Clinical Trial Update: Let's Get REAL: Family Health Communication Tool in Pediatric Stem Cell Transplant and Cellular Therapy [NA]
This ClinicalTrials.gov entry describes a pediatric stem cell transplant and cellular therapy trial evaluating a family health communication…
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CLINICAL_TRIALS research · 2025-11-26Clinical Trial Update: Ruxolitinib-Enhanced Haplo HCT for Children and Young Adults With Sickle Cell Disease [Phase 1, Phase 2]
A Phase 1/2 trial investigating ruxolitinib-enhanced haploidentical hematopoietic stem cell transplantation for children and young adults wi…
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CLINICAL_TRIALS research · 2025-11-18Clinical Trial Update: Collect of Cord Blood From Subjects at Risk for Sickle Cell Disease, for the Purpose of Laboratory Research
A completed clinical trial from France collected cord blood from subjects at risk for sickle cell disease for laboratory research.