Sickle Cell Disease
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2026-04-15Clinical Trial Update: OMEGA-3-FATTY ACIDS IN CHILDREN WITH SICKLE CELL DISEASE [NA]
A clinical trial update shows a study evaluating omega-3 fatty acids in children with sickle cell disease. The study is currently not yet re…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Open-Label Extension Study to Pioneer Study 6058-SCD-101 [Phase 2]
Open-label extension of the Phase 2 Pioneer study 6058-SCD-101 for sickle cell disease. Enrollment is by invitation and ongoing.
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Acceptance and Commitment Therapy for Adolescents and Young Adults With Sickle Cell Disease [Phase 1, Phase 2]
A phase 1/2 clinical trial is evaluating Acceptance and Commitment Therapy for adolescents and young adults with sickle cell disease. The st…
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CLINICAL_TRIALS research · 2026-04-14Clinical Trial Update: Managed Access Programs for SEG101, Crizanlizumab
Clinical trial update describing managed access programs for crizanlizumab (SEG101) for sickle cell disease.
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: The Efficacy and Safety of Rilzabrutinib in Participants Aged 10 to 65 Years With Sickle-cell Disease [Phase 3]
Phase 3 clinical trial update investigating the efficacy and safety of rilzabrutinib in participants aged 10 to 65 with sickle cell disease;…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Alendronate for Osteonecrosis in Adults With Sickle Cell Disease [Phase 2]
A Phase 2 clinical trial is evaluating alendronate for treating osteonecrosis in adults with sickle cell disease and is currently recruiting…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Intravenous L-Citrulline for Vaso-occlusive Pain Episode in Sickle Cell Disease [Phase 2]
This is a Phase 2 clinical trial evaluating intravenous L-Citrulline for vaso-occlusive pain episodes in sickle cell disease, currently recr…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Sickle Cell Disease Obstetric Multi-Disciplinary Care Programme
A Vanderbilt-led clinical trial on an obstetric multidisciplinary care program for patients with sickle cell disease is currently active but…
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CLINICAL_TRIALS research · 2026-04-13Clinical Trial Update: Sickle Cell Kidney Biorepository
A UT Southwestern Medical Center-sponsored clinical trial registry entry for a Sickle Cell Kidney Biorepository, currently recruiting to col…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Alternative Dosing And Prevention of Transfusions (ADAPT) [EARLY_Phase 1]
Early Phase 1 clinical trial (ADAPT) at Cincinnati Children's Hospital evaluating alternative dosing and prevention of transfusions in sickl…
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CLINICAL_TRIALS research · 2026-04-09Clinical Trial Update: Ultrasound Acute Chest Syndrome Sickle Cell Disease [NA]
A clinical trial update shows an ultrasound study evaluating treatment for Acute Chest Syndrome in Sickle Cell Disease is currently recruiti…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Insights Into Microbiome and Environmental Contributions to Sickle Cell Disease and Leg Ulcers Study (INSIGHTS Study)
A completed NHGRI-sponsored clinical study (INSIGHTS) investigates how the microbiome and environmental factors influence sickle cell diseas…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Blood Collection for Research Related to Certain Diseases Involving Blood Vessels
This update describes ongoing blood collection for research related to diseases involving blood vessels, including sickle cell disease. Enro…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: A Study of Immune Suppression Treatment for People With Sickle Cell Disease or β-Thalassemia Who Are Going to Receive an Allogeneic Hematopoietic Cell Transplantation (HCT) [Phase 2]
This is a Phase 2 clinical trial evaluating an immune suppression treatment for people with sickle cell disease or beta-thalassemia undergoi…
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CLINICAL_TRIALS research · 2026-04-08Clinical Trial Update: Living With Sickle Cell Disease in the COVID-19 Pandemic
This clinical trial update reports on a completed study sponsored by NHGRI evaluating the experiences of people with sickle cell disease dur…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: Tocilizumab for Acute Chest Syndrome [Phase 2]
This is a Phase 2 clinical trial evaluating Tocilizumab for Acute Chest Syndrome in patients with sickle cell disease; recruitment is ongoin…
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CLINICAL_TRIALS research · 2026-04-06Clinical Trial Update: A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS) [Phase 3]
Phase 3 trial update for etavopivat in adults and adolescents with sickle cell disease (HIBISCUS). The study is currently active but not rec…
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CLINICAL_TRIALS research · 2026-04-02Clinical Trial Update: Sickle Cell, Pain and Mediterranean Diet [NA]
An update about a University of Illinois at Chicago clinical trial investigating sickle cell pain management with a Mediterranean diet, curr…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Pathophysiology of Acute Pain in Patients With Sickle Cell Disease
This clinical trial update reports on a completed NHLBI study investigating the mechanisms underlying acute pain in patients with sickle cel…
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CLINICAL_TRIALS research · 2026-04-01Clinical Trial Update: Acupressure in Patients With Sickle Cell Disease [NA]
The ClinicalTrials.gov entry notes an acupressure study in patients with Sickle Cell Disease sponsored by Indiana University, currently list…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell Disease [Phase 1]
Phase 1 clinical trial evaluating the single-dose pharmacokinetics of Pociredir in participants with sickle cell disease. The study is curre…
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CLINICAL_TRIALS research · 2026-03-30Clinical Trial Update: Sickle Cell Disease and the Genomic and Gene Therapy Needs of Stakeholders
The clinical trial NCT04416178 sponsored by St. Jude Children’s Research Hospital, focused on genomic and gene therapy needs for sickle cell…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: Evaluation of the Efficacy of Iloprost in the Management of Vaso-occlusive Crises in Adult Patients With Sickle Cell Disease [Phase 3]
Phase 3 clinical trial evaluating iloprost for managing vaso-occlusive crises in adults with sickle cell disease; the study is not yet recru…
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CLINICAL_TRIALS research · 2026-03-27Clinical Trial Update: A Study to Investigate the Efficacy and Safety of Crizanlizumab (5 mg/kg) Compared With Placebo in Adolescent and Adult Sickle Cell Disease Patients Who Experience Frequent Vaso-Occlusive Crises (SPARKLE) [Phase 3]
Phase 3 study to evaluate crizanlizumab (5 mg/kg) vs placebo in adolescents and adults with sickle cell disease and frequent vaso-occlusive …
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CLINICAL_TRIALS research · 2026-03-24Clinical Trial Update: A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia [Phase 3]
This is an update on a Phase 3 clinical trial evaluating long-term treatment with etavopivat in people with Sickle Cell Disease or Thalassem…