Sickle Cell Disease
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CLINICAL_TRIALS research · 2024-07-12Clinical Trial Update: Role of Transcranial Doppler and Magnetic Resonance Angiography for Future Management of Sickle Cell Anemia CNS.
This clinical trial update discusses the potential role of Transcranial Doppler and Magnetic Resonance Angiography in managing CNS complicat…
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CLINICAL_TRIALS research · 2024-07-11Clinical Trial Update: Lung Ultrasound in Pediatric Acute Chest Syndrome
A pediatric trial evaluating lung ultrasound for acute chest syndrome in sickle cell disease is currently recruiting.
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CLINICAL_TRIALS research · 2024-06-21Clinical Trial Update: Pediatric -Adult Care Transition Program of Patients With Sickle Cell Disease [NA]
Clinical trial update indicates ongoing recruitment for a pediatric-to-adult care transition program in patients with Sickle Cell Disease.
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CLINICAL_TRIALS research · 2024-06-17Clinical Trial Update: ASH Research Collaborative Data Hub
The ASH Research Collaborative Data Hub trial is currently enrolling by invitation for Sickle Cell Disease and Multiple Myeloma. This entry …
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CLINICAL_TRIALS research · 2024-06-03Clinical Trial Update: Clinical Study on the Safety and Efficacy of BRL-101 in the Treatment of Sickle Cell Disease [NA]
A clinical study is evaluating BRL-101 for treating sickle cell disease, assessing safety and efficacy, with recruitment not yet started.
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Effect of NUV001 Supplementation in Patients Suffering From Sickle Cell Disease (SCD) [NA]
This document notes an active-not-recruiting clinical trial evaluating NUV001 supplementation in patients with Sickle Cell Disease.
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CLINICAL_TRIALS research · 2024-05-28Clinical Trial Update: Safety and Efficacy of Orally Administered NUV001 Nutraceutical Supplement in Sickle Cell Disease Patients [NA]
This document provides an update on a clinical trial assessing the safety and efficacy of the orally administered NUV001 nutraceutical suppl…
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CLINICAL_TRIALS research · 2024-05-16Clinical Trial Update: LEARNER- Low dosE AspiRiN prEterm tRial (Angola) [Phase 1, Phase 2]
This clinical trial update describes the LEARNER trial evaluating low-dose aspirin for sickle cell disease and pregnancy-related complicatio…
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CLINICAL_TRIALS research · 2024-05-13Clinical Trial Update: A Trial to Assess Haploidentical T-depleted Stem Cell Transplantation in Patients With SCD [Phase 2]
A Phase 2 clinical trial is evaluating haploidentical T-depleted stem cell transplantation in patients with sickle cell disease.
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CLINICAL_TRIALS research · 2024-04-29Clinical Trial Update: Low Systemic/High Local Exercise Load in Peds SCD [NA]
The update describes a pediatric sickle cell disease study investigating low systemic and high local exercise load, sponsored by the Univers…
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CLINICAL_TRIALS research · 2020-11-02Clinical Trial Update: Novel Cardiac Magnetic Resonance Imaging to Define a Unique Restrictive Cardiomyopathy in Sickle Cell Disease
A completed clinical trial evaluating cardiac MRI to define a specific restrictive cardiomyopathy in patients with sickle cell disease; resu…
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CLINICAL_TRIALS research · 2020-10-19Clinical Trial Update: Carbon Monoxide Measurement to Screen for Sickle Cell Disease [NA]
A completed clinical trial investigating carbon monoxide measurement as a screening tool for sickle cell disease.
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CLINICAL_TRIALS research · 2020-10-12Clinical Trial Update: Central Nervous System Vascular Changes in Adult Sickle Cell Disease and the Effect of Treatment With Simvastatin [Phase 1, Phase 2]
Phase 1/2 trial evaluating central nervous system vascular changes in adult sickle cell disease and the effect of simvastatin treatment.
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CLINICAL_TRIALS research · 2020-07-09Clinical Trial Update: A Pilot Study of N-acetylcysteine in Patients With Sickle Cell Disease [Phase 1, Phase 2]
Pilot phase 1/2 trial evaluating N-acetylcysteine in patients with sickle cell disease.
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CLINICAL_TRIALS research · 2019-02-12Clinical Trial Update: New Hemolysis Parameters in Sickle Cell Disease
This clinical trial update discusses the exploration of new hemolysis parameters in sickle cell disease. The trial status is listed as unkno…
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CLINICAL_TRIALS research · 2019-02-06Clinical Trial Update: Evaluation of Knowledge Among Adolescents With Sickle Cell Disease.
This clinical trial update reports on evaluating knowledge among adolescents with Sickle Cell Disease; the study status is completed.
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CLINICAL_TRIALS research · 2019-02-01Clinical Trial Update: A Sickle CEll Disease ComplicatioN Trial [Phase 3]
Phase 3 trial evaluating Micelle BioPharma Inc's investigational product for sickle cell disease; current status is UNKNOWN.
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CLINICAL_TRIALS research · 2018-07-12Clinical Trial Update: Survey in a Population of Sickle Cell Disease Patients to Evaluate the Transition Between the Queen Fabiola Children Hospital and the CHU Brugmann Hospital, and the Quality of the Hospital Care Within the CHU Brugmann Hospital. [NA]
A completed clinical trial update surveying sickle cell disease patients to evaluate the transition between two hospitals and assess the qua…
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CLINICAL_TRIALS research · 2018-06-15Clinical Trial Update: Sickle Cell Disease (SCD) Decision Aid [NA]
A clinical trial update describes a decision aid for sickle cell disease sponsored by Emory University, and the study status is completed.
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CLINICAL_TRIALS research · 2018-05-25Clinical Trial Update: Heart Arteries and Sickle Cell Disease / Coeur Artères DREpanocytose
Clinical trial update from Cardiologie et Développement regarding sickle cell anemia and sickle cell disease. The trial status is listed as …
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CLINICAL_TRIALS research · 2018-05-04Clinical Trial Update: Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG
This entry reports a completed ancillary transcranial Doppler ultrasound study conducted on subjects enrolled in the BABY HUG sickle cell tr…
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CLINICAL_TRIALS research · 2018-05-03Clinical Trial Update: A Comprehensive Care Plan for Pediatric Patients With Vaso-Occlusive Crises [NA]
A clinical trial update describes a comprehensive care plan for pediatric patients with vaso-occlusive crises, sponsored by Valley Anesthesi…
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CLINICAL_TRIALS research · 2017-12-11Clinical Trial Update: Implication of the Oxydative Stress in the Pathophysiology of Sickle Cell Anemia: [NA]
A completed clinical trial update examining the role of oxidative stress in the pathophysiology of sickle cell disease.
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CLINICAL_TRIALS research · 2017-11-24Clinical Trial Update: Substudy of CADRE: for People With Extreme Phenotype: BIOCADRE
A clinical trial substudy (BIOCADRE) under the CADRE program is planned for people with extreme phenotype in sickle cell disease; sponsor is…
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CLINICAL_TRIALS research · 2017-11-20Clinical Trial Update: Autologous Bone Marrow Stem Cell Transplantation for Osteonecrosis in Sickle Cell Disease [Phase 1, Phase 2]
This entry provides an update on a Phase 1/Phase 2 clinical trial evaluating autologous bone marrow stem cell transplantation for osteonecro…