Septic Shock
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS research · 2025-04-10Clinical Trial Update: Cerebral Hemodynamics and Oxygenation in Critically Ill Patients
This clinical trial investigates cerebral hemodynamics and oxygenation in critically ill patients with septic shock; the study is currently …
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients [NA]
A clinical trial at Ain Shams University is comparing Interleukin-6 and procalcitonin as markers to detect sepsis and assess mortality in bu…
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CLINICAL_TRIALS research · 2025-04-08Clinical Trial Update: Shenfu Injection Modulates Carotid Elasticity in Septic Shock [Phase 4]
Phase 4 clinical trial update indicates Shenfu Injection is being studied for its effects on carotid elasticity in septic shock. Recruitment…
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CLINICAL_TRIALS research · 2025-04-06Clinical Trial Update: Protocolised Early De-Resuscitation in Septic Shock (REDUCE) [NA]
A protocolised early de-resuscitation trial in septic shock is listed as active but not recruiting. Sponsor institutions include Insel Grupp…
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02) [Phase 3]
Phase III open-label, randomized study evaluating VBI-S for treatment of hypovolemia in patients with septic shock; currently recruiting.
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CLINICAL_TRIALS research · 2025-04-04Clinical Trial Update: The Effect of Vasopressor Therapy on Renal Perfusion in Septic Shock [NA]
This ongoing clinical trial evaluates how vasopressor therapy affects renal perfusion in patients with septic shock and acute kidney injury …
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CLINICAL_TRIALS trial_result · 2025-04-03Clinical Trial Update: The Effect of Restrictive Fluid Management on Cardiac Function and Glycocalyx Degradation [Phase 4]
Phase 4 clinical trial evaluating the effects of restrictive fluid management on cardiac function and glycocalyx degradation in septic shock…
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CLINICAL_TRIALS research · 2025-04-01Clinical Trial Update: Study on the Construction and Application of Early Warning Model of Sepsis in Critically Ill Patients
An ongoing clinical trial from the Second Affiliated Hospital of Wenzhou Medical University is evaluating an early warning model for sepsis …
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CLINICAL_TRIALS other · 2025-04-01Clinical Trial Update: Sevoflurane Sedation in Patients With Septic Shock [Phase 2]
Phase 2 clinical trial evaluating sevoflurane for sedation in septic shock; status not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-03-30Clinical Trial Update: Impact of Prior SGLT2 Inhibitors Use on the Development and Progression of Sepsis-Associated Acute Kidney Injury
This clinical trial update investigates whether prior use of SGLT2 inhibitors affects the development and progression of sepsis-associated a…
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CLINICAL_TRIALS research · 2025-03-27Clinical Trial Update: The Preventive Effect of Shenfu Injection on Myocardial Dysfunction in Sepsis [Phase 4]
Phase 4 clinical trial update evaluating Shenfu Injection for preventing myocardial dysfunction in sepsis, with recruitment ongoing for sept…
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FDA approval · 2025-03-21FDA Approved: NOREPINEPHRINE BITARTRATE — Original Application (BIOCON PHARMA INC.)
FDA approved Biocon Pharma Inc. for an Original Application of norepinephrine bitartrate (norepinephrine bitartrate) as a generic product. I…
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CLINICAL_TRIALS trial_result · 2025-03-17Clinical Trial Update: Procalcitonin and Antimicrobial Utilization in Critically Ill Cancer Patients with Sepsis [NA]
ClinicalTrials.gov update on a terminated study evaluating procalcitonin-guided antimicrobial use in critically ill cancer patients with sep…
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: First in Human Trial to Assess the Feasibility and Preliminary Safety of Adjunctive Treatment with the HemoSystem REBOOT in Critically Ill Patients with Sepsis-induced Immunosuppression [NA]
This clinical trial update announces a first-in-human study to assess feasibility and preliminary safety of HemoSystem REBOOT as an adjuncti…
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CLINICAL_TRIALS trial_result · 2025-03-14Clinical Trial Update: Hypotension in the Weaning From Vasopressor Drugs [Phase 4]
Phase 4 clinical trial evaluating hypotension during weaning from vasopressor therapy in septic shock has completed.
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CLINICAL_TRIALS research · 2025-03-14Clinical Trial Update: Effects of Intravenous Metabolic Recovery Agent in Elderly Septic Patients on Prognosis and Microcirculation. [NA]
A clinical trial update announcing ongoing recruitment for a study of an Intravenous Metabolic Recovery Agent in elderly septic shock patien…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Evaluation of Hemodynamic Effects of Cascade Hemofiltration in Septic Shock [NA]
Completed clinical trial evaluating the hemodynamic effects of cascade hemofiltration in septic shock.
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: Efficacy of Add-on Plasma Exchange As an Adjunctive Strategy Against Septic Shock [NA]
This clinical trial update reports on evaluating add-on plasma exchange as an adjunctive therapy for septic shock; the study is currently re…
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CLINICAL_TRIALS trial_result · 2025-03-13Clinical Trial Update: High Cut-Off Continuous Veno-venous Hemodialysis (CVVHD) in Patients Treated for Acute Renal Failure After Systemic Inflammatory Response Syndrome (SIRS)/Septic Shock [NA]
A terminated clinical trial evaluating high cut-off CVVHD in patients with acute kidney failure after systemic inflammatory response syndrom…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Evaluation of Early Administration of Levetiracetam in the Prevention and Treatment Encephalopathy in Septic Shock: Randomized, Double-blind, Placebo-controlled Trial [Phase 3]
A Phase 3 randomized, double-blind, placebo-controlled trial evaluating early administration of levetiracetam to prevent and treat encephalo…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Ultrasound-guided Blood Sampling Drawing for Microbiological Analysis in the Critically Ill
The document outlines a clinical trial evaluating ultrasound-guided blood sampling for microbiological analysis in critically ill patients w…
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CLINICAL_TRIALS research · 2025-03-12Clinical Trial Update: Renin Levels as Prognostic Indicators of Septic Shock Severity and Outcome
A clinical trial is investigating whether renin levels can serve as prognostic indicators for severity and outcomes in septic shock and is c…
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CLINICAL_TRIALS research · 2025-03-07Clinical Trial Update: Hemodynamic Measurements of Macrocirculatory and Perfusion Parameters in ICU
This clinical trial is recruiting in the ICU to measure macrocirculatory and perfusion parameters in patients with septic shock. The study i…
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CLINICAL_TRIALS trial_result · 2025-03-05Clinical Trial Update: ALBumin Italian Outcome Septic Shock-BALANCED Trial (ALBIOSS-BALANCED) [Phase 3]
This update notes that the ALBIOSS-BALANCED Phase 3 trial evaluating albumin therapy for septic shock has completed.
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: Midodrine Effect on the Mortality Rates in Septic Shock Patients [Phase 2]
Phase 2 trial evaluating midodrine's effect on mortality in septic shock has completed.