Septic Shock
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-03-03Clinical Trial Update: PCT Guided Stopping of Antibiotic Therapy in Children With Sepsis [NA]
A pediatric sepsis trial evaluated stopping antibiotic therapy early using procalcitonin guidance; the study has completed.
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CLINICAL_TRIALS research · 2025-03-03Clinical Trial Update: Ventriculo-arterial Coupling and Myocardial Work in Sepsis and Septic Shock [NA]
A clinical trial investigating ventriculo-arterial coupling and myocardial work in sepsis and septic shock is listed as not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-02-24Clinical Trial Update: The Conservative vs. Liberal Approach to Fluid Therapy of Septic Shock in Intensive Care Trial [Phase 4]
A Phase 4 trial comparing conservative versus liberal fluid therapy in septic shock has completed and posted results.
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CLINICAL_TRIALS research · 2025-02-24Clinical Trial Update: Evaluating Dynamic Arterial Elastance in Septic Shock Patients. [NA]
This record notes a clinical trial evaluating dynamic arterial elastance in patients with septic shock. The study is currently not yet recru…
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CLINICAL_TRIALS trial_result · 2025-02-19Clinical Trial Update: Use of Neurostimulation As a Tool for Reconditioning the Neuromuscular System of Patients Admitted to the ICU for Septic Shock [NA]
The clinical trial evaluating neurostimulation to recondition the neuromuscular system in ICU patients with septic shock has been terminated…
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CLINICAL_TRIALS research · 2025-02-13Clinical Trial Update: Evaluation of Blood Protein O-GlcNAcylation Levels in Children
ClinicalTrials.gov shows a pediatric study evaluating blood protein O-GlcNAcylation levels in children with sepsis and septic shock that is …
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CLINICAL_TRIALS trial_result · 2025-02-11Clinical Trial Update: Intravenously Administered M6229 in Critically Ill Sepsis Patients [Phase 1]
Phase 1 trial of intravenously administered M6229 in patients with sepsis and septic shock has completed.
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CLINICAL_TRIALS research · 2025-02-05Clinical Trial Update: Study on the Improvement of Microcirculation in Patients With Sepsis by Vitamin B6, Vitamin B12 and Vitamin C [NA]
A clinical trial evaluating whether vitamin B6, vitamin B12, and vitamin C can improve microcirculation in patients with septic shock; the s…
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FDA approval · 2025-01-31FDA Approved: NOREPINEPHRINE BITARTRATE — Original Application (Camber Pharmaceuticals, Inc.)
FDA approves Camber Pharmaceuticals' norepinephrine bitartrate as an original application (generic) product.
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CLINICAL_TRIALS trial_result · 2025-01-29Clinical Trial Update: Intravenous Metoprolol in Septic Shock [Phase 2]
A Phase 2 trial evaluating intravenous metoprolol in septic shock has completed, including patients with ventilator-associated pneumonia.
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CLINICAL_TRIALS research · 2025-01-22Clinical Trial Update: Types of Photoplethysmographic Waves in Adult Patients with Septic Shock
A clinical trial evaluating different photoplethysmographic waveforms in adult patients with septic shock; currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-01-17Clinical Trial Update: Citrulline and Arginase Activity in Severe Sepsis and Septic Shock
A completed clinical trial investigating citrulline levels and arginase activity in patients with severe sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2025-01-16Clinical Trial Update: PK/PD of Extended-infusion Meropenem, Piperacillin-tazobactam and Cefepime in the Early Phase of Septic Shock [Phase 3]
Phase 3 trial update reports pharmacokinetic/pharmacodynamic data for extended-infusion meropenem, piperacillin-tazobactam, and cefepime in …
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CLINICAL_TRIALS research · 2025-01-09Clinical Trial Update: Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis [Phase 4]
Phase 4 clinical trial assessing optimized exposure of beta-lactam antibiotics in critically ill patients with sepsis, currently recruiting.
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Pentaglobin in CRE and PA Neutropenic Infections [Phase 2]
Phase 2 clinical trial update for Pentaglobin in neutropenic infections due to CRE and Pseudomonas aeruginosa in septic shock; the study is …
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Effects of Paroxetine on Cardiovascular Function in Septic Patients [Phase 2]
A Phase 2 clinical trial is investigating the effects of paroxetine on cardiovascular function in patients with septic shock or sepsis, and …
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CLINICAL_TRIALS research · 2025-01-06Clinical Trial Update: Doppler Echocardiography Versus Clinical Targets Guided Therapy on the Outcome of Postpartum Septic Shock. [NA]
This clinical trial compares Doppler echocardiography-guided therapy to clinically guided therapy for outcomes in postpartum septic shock, a…
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CLINICAL_TRIALS trial_result · 2025-01-03Clinical Trial Update: Evaluating the Effect of Chronic Antihypertensive Therapy on Vasopressor Dosing in Septic Shock
This clinical trial evaluated whether chronic antihypertensive therapy influences vasopressor dosing requirements in septic shock. The study…
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CLINICAL_TRIALS research · 2025-01-03Clinical Trial Update: Restricted or Liberal Fluid for Haemodynamic Resuscitation in Sepsis
A registered clinical trial compares restricted versus liberal fluid administration for hemodynamic resuscitation in septic shock, with stat…
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CLINICAL_TRIALS research · 2024-12-30Clinical Trial Update: Efficacy and Safety of Methylene Blue in the Treatment of Severe Septic Shock [NA]
A clinical trial is evaluating the efficacy and safety of methylene blue for the treatment of severe septic shock and is currently recruitin…
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CLINICAL_TRIALS research · 2024-12-27Clinical Trial Update: Use of Epoetin Alfa and Iron Derisomaltose in Treatment of Anemia in Patients With Sepsis or Septic Shock: a Randomized Controlled Trial [Phase 4]
Phase 4 randomized controlled trial evaluating epoetin alfa with iron isomaltose for treating anemia in patients with sepsis or septic shock…
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CLINICAL_TRIALS trial_result · 2024-12-20Clinical Trial Update: Rotational Thromboelastometry Versus DIC Score in Sepsis
An update on a completed clinical trial comparing rotational thromboelastometry to the DIC score in sepsis and septic shock.
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Vitamin C, Hydrocortisone and Thiamine for Septic Shock [Phase 2]
A Phase 2 trial evaluating the combination of vitamin C, hydrocortisone, and thiamine for septic shock was terminated.
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CLINICAL_TRIALS research · 2024-12-19Clinical Trial Update: Role of Ivabradine for Heart Rate Control in Management of Patients With Sepsis and Septic Shock [NA]
A clinical trial is evaluating ivabradine for heart rate control in patients with sepsis and septic shock; the study status is not yet recru…
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CLINICAL_TRIALS trial_result · 2024-12-19Clinical Trial Update: Vitamin C, Steroids, and Thiamine, and Cerebral Autoregulation and Functional Outcome in Septic Shock [Phase 1, Phase 2]
A Phase 1/Phase 2 clinical trial evaluating high-dose vitamin C, hydrocortisone, and thiamine for septic shock, assessing cerebral autoregul…