Septic Shock
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Sign up freeTop drugs studied for this disease
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CLINICAL_TRIALS trial_result · 2025-08-26Clinical Trial Update: L-carnitine as an Adjunct Treatment for Septic Shock Patients With Acute Kidney Injury [Phase 3]
A Phase 3 trial investigating L-carnitine as an adjunct treatment for septic shock patients with acute kidney injury has been terminated.
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CLINICAL_TRIALS trial_result · 2025-08-24Clinical Trial Update: Optimization of Sepsis Therapy Based on Patient-specific Digital Precision Diagnostics [NA]
A completed clinical trial evaluating optimization of sepsis therapy guided by patient-specific digital precision diagnostics.
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Comparison of Landiolol Versus Standard of Care for Prevention of Mortality in Patients Hospitalized for a Septic Shock With Hypercontractility [Phase 3]
This document describes a Phase 3 clinical trial comparing landiolol to standard of care for preventing mortality in patients with septic sh…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock? [Phase 3]
This update describes a Phase 3 trial assessing whether high-dose nicotinamide (Vitamin B3) can prevent major adverse kidney events in septi…
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CLINICAL_TRIALS research · 2025-08-24Clinical Trial Update: Microvascular Monitoring in Circulatory Shock and Sepsis (MiMICSS)
A University of Manitoba-led clinical trial evaluating microvascular monitoring in circulatory shock and sepsis is currently recruiting. It …
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CLINICAL_TRIALS research · 2025-08-22Clinical Trial Update: Prediction of Fluid Responsiveness in Paediatric Patients With Septic Shock Using Carotid Doppler Ultrasonography and Echocardiography
Clinical trial investigating prediction of fluid responsiveness in pediatric septic shock using carotid Doppler ultrasonography and echocard…
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CLINICAL_TRIALS research · 2025-08-17Clinical Trial Update: Therapeutic Plasma Exchange in Septic Shock: A Pilot Study [Phase 2]
A Phase 2 clinical trial evaluating therapeutic plasma exchange for septic shock is currently recruiting.
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CLINICAL_TRIALS research · 2025-08-15Clinical Trial Update: Prognostic Power of the VEXUS Score in Septic Shock: Effectiveness in Mortality Prediction
The trial examines whether the VEXUS ultrasound score can predict mortality in septic shock, and is currently listed as not yet recruiting.
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CLINICAL_TRIALS trial_result · 2025-08-11Clinical Trial Update: LIPIDS-P Trial Phase I/II Trial [Phase 1, Phase 2]
The LIPIDS-P trial, a Phase I/II study, has completed and posted results evaluating its safety and preliminary efficacy in sepsis and septic…
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CLINICAL_TRIALS research · 2025-08-08Clinical Trial Update: Systematic Adjunction of Vasopressine in Septic Shock [Phase 3]
A Phase 3 clinical trial evaluating the adjunctive use of vasopressin in septic shock; the study is not yet recruiting.
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CLINICAL_TRIALS other · 2025-08-05Clinical Trial Update: A RCT to Assess the Performance of CytoSorb for Shock Reversal in Patients With Vasoplegic Septic Shock [NA]
The randomized trial evaluating CytoSorb for shock reversal in vasoplegic septic shock has been suspended.
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CLINICAL_TRIALS trial_result · 2025-08-03Clinical Trial Update: Multicenter Symphony IL-6 Monitoring Sepsis ICU Study
A multicenter clinical trial evaluating interleukin-6 monitoring in ICU patients with sepsis has completed.
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CLINICAL_TRIALS research · 2025-08-01Clinical Trial Update: LANdiolol MIcrocirculatory Effects During Septic chOc (MILANOS) [Phase 3]
A Phase 3 clinical trial evaluating the microcirculatory effects of landiolol in patients with septic shock, currently recruiting.
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CLINICAL_TRIALS trial_result · 2025-07-29Clinical Trial Update: Recombinant Human Brain Natriuretic Peptide for the Recovery Stage of Septic Shock [NA]
This clinical trial is evaluating recombinant human brain natriuretic peptide for the recovery phase of septic shock in patients with sepsis…
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CLINICAL_TRIALS research · 2025-07-28Clinical Trial Update: Can Gdf-15 Level Predict Progression to Multiple Organ Failure in Patients With Septic Shock
This clinical trial update notes a study investigating whether GDF-15 levels can predict progression to multiple organ dysfunction syndrome …
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CLINICAL_TRIALS research · 2025-07-24Clinical Trial Update: Clinical Performance Study of Microbio InfectID-BSI for Detection of Bacteria and Yeast With Patient Blood Samples
A clinical performance study of Microbio InfectID-BSI for detecting bacteria and yeast in patient blood samples is described, with the study…
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CLINICAL_TRIALS research · 2025-07-16Clinical Trial Update: Molecular Subtype-Specific Mechanisms and Therapeutic Strategies in Sepsis
An ongoing clinical trial from Mater Dei Hospital Malta examines molecular subtype–specific mechanisms and therapies for sepsis and septic s…
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CLINICAL_TRIALS trial_result · 2025-07-11Clinical Trial Update: Evaluation of Droplet Digital PCR Rapid Detection Method and Precise Diagnosis and Treatment for Suspected Sepsis [NA]
This clinical trial update reports the completed evaluation of a droplet digital PCR rapid detection method aimed at enabling precise diagno…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Focused Ultrasound Spleen Stimulation and Inflammation in Septic Shock [NA]
Clinical trial update for a study evaluating focused ultrasound–mediated spleen stimulation to modulate inflammation in septic shock. The st…
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CLINICAL_TRIALS research · 2025-07-04Clinical Trial Update: Xanthohumol as an Adjuvant in the Treatment of Septic Shock [Phase 2]
Phase 2 clinical trial update on Xanthohumol as an adjuvant therapy for septic shock, with recruitment ongoing; the study lists septic shock…
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CLINICAL_TRIALS research · 2025-07-03Clinical Trial Update: Critical Closing Pressure and PCO₂ Gap in Fluid Resuscitation for Septic Shock
This clinical trial update indicates that the study on critical closing pressure and the PCO2 gap in fluid resuscitation for septic shock is…
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CLINICAL_TRIALS trial_result · 2025-07-03Clinical Trial Update: Empirical Meropenem Versus Piperacillin/Tazobactam for Adult Patients With Sepsis [Phase 4]
A Phase 4 clinical trial comparing empirical meropenem versus piperacillin/tazobactam in adults with sepsis (including septic shock) is curr…
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CLINICAL_TRIALS research · 2025-07-02Clinical Trial Update: Albumin and Crystalloid Administration in Septic Shock [Phase 4]
Phase 4 clinical trial evaluating albumin versus crystalloid fluid administration in septic shock; currently recruiting.
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CLINICAL_TRIALS research · 2025-07-01Clinical Trial Update: Early Initiated Vasopressor Therapy in the Emergency Department [Phase 3]
Phase 3 clinical trial evaluating early initiation of vasopressor therapy in the emergency department for patients with shock, including sep…
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CLINICAL_TRIALS research · 2025-06-29Clinical Trial Update: "Mini Fluid Challenge Assessment: a Comparison Among Three Hemodynamic Tools"
A clinical trial update describes a study comparing three hemodynamic tools for mini-fluid challenge assessment in sepsis and critically ill…